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Browsing by Author "Kalland, Karl-Henning"

Bergen Open Research Archive

Browsing by Author "Kalland, Karl-Henning"

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  • Tabach, Yuval; Kogan-Sakin, Ira; Buganim, Yosef; Solomon, Hilla; Goldfinger, Naomi; Hovland, Randi; Ke, Xi-Song; Øyan, Anne Margrete; Kalland, Karl-Henning; Rotter, Varda; Domany, Eytan (Peer reviewed; Journal article, Public Library of Science, 2011-01-31)
    Duplication of chromosomal arm 20q occurs in prostate, cervical, colon, gastric, bladder, melanoma, pancreas and breast cancer, suggesting that 20q amplification may play a causal role in tumorigenesis. According to an ...
  • Ke, Xi-Song; Qu, Yi; Goldfinger, Naomi; Rostad, Kari; Hovland, Randi; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning (Peer reviewed; Journal article, Public Library of Science, 2008-10-13)
    Background: Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro. EMT has been induced in prostate cancer cell ...
  • Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug (Peer reviewed; Journal article, BioMed Central Ltd., 2012-01-17)
    Background The tumor microenvironment is pivotal in tumor progression. Thus, we aimed to develop a mammary tumor model to elucidate molecular characteristics in the stroma versus the tumor cell compartment ...
  • Ke, Xi-Song; Qu, Yi; Cheng, Yang; Li, Wen-Cheng; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning (Peer reviewed; Journal article, BioMed Central, 2010-11-25)
    Background Previously we reported extensive gene expression reprogramming during epithelial to mesenchymal transition (EMT) of primary prostate cells. Here we investigated the hypothesis that specific histone and DNA ...
  • Krakstad, Camilla; Birkeland, Even; Seidel, Danila; Kusonmano, Kanthida; Petersen, Kjell; Mjøs, Siv; Høivik, Erling Andre; Wik, Elisabeth; Halle, Mari Kyllesø; Øyan, Anne Margrete; Kalland, Karl-Henning; Werner, Henrica Maria Johanna; Trovik, Jone; Salvesen, Helga B. (Peer reviewed; Journal article, Public Library of Science, 2012-12-27)
    Background: Despite being the most common pelvic gynecologic malignancy in industrialized countries, no targeted therapies are available for patients with metastatic endometrial carcinoma. In order to improve treatment, ...
  • Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug (Journal article; Peer reviewed, Public Library of Science, 2009-07-28)
    Tumor hypoxia is relevant for tumor growth, metabolism and epithelial-to-mesenchymal transition (EMT). We report that hyperbaric oxygen (HBO) treatment induced mesenchymal-to-epithelial transition (MET) in a dimetyl-a-b ...
  • Ræder, Maria B.; Birkeland, Even; Trovik, Jone; Krakstad, Camilla; Shehata, Shyemaa; Schumacher, Steven; Zack, Travis I.; Krohn, Antje; Werner, Henrica Maria Johanna; Moody, Susan E.; Wik, Elisabeth; Stefansson, Ingunn Marie; Holst, Frederik; Øyan, Anne Margrete; Tamayo, Pablo; Mesirov, Jill P.; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Beroukhim, Rameen; Salvesen, Helga B. (Peer reviewed; Journal article, Public Library of Science, 2013-02-05)
    Chromosome 8q24 is the most commonly amplified region across multiple cancer types, and the typical length of the amplification suggests that it may target additional genes to MYC. To explore the roles of the genes most ...
  • Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B.; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Krakstad, Camilla; Salvesen, Helga B. (Peer reviewed; Journal article, Cancer Research UK and Nature Publishing Group, 2012)
    BACKGROUND: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect from systemic therapies. Homo sapiens v-Ki-ras2 Kirsten rat ...
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Wik, Elisabeth; Kusonmano, Kanthida; Ræder, Maria B.; Øyan, Anne Margrete; Kalland, Karl-Henning; Moses, Marsha A.; Salvesen, Helga B.; Akslen, Lars A. (Peer reviewed; Journal article, BioMed Central, 2012-05-06)
    Background: Increased expression of lipocalin 2 (LCN2) has been observed in several cancers. The aim of the present study was to investigate LCN2 in endometrial cancer in relation to clinico-pathologic phenotype, angiogenesis, ...

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