Now showing items 1-3 of 3

  • DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response 

    Dejeux, Emelyne; Rønneberg, Jo A.; Solvang, Hiroko Kato; Bukholm, Ida Rashida Khan; Geisler, Stephanie; Aas, Turid; Gut, Ivo G.; Børresen-Dale, Anne-Lise; Lønning, Per Eystein; Kristensen, Vessela N.; Tost, Jörg (BioMed Central, 2010-03-25)
    Background: Breast cancer is the most frequent cancer in women and consists of a heterogeneous collection of diseases with distinct histopathological, genetic and epigenetic characteristics. In this study, we aimed to ...
    Peer reviewedJournal article
  • Multilocus analysis of SNP and metabolic data within a given pathway 

    Kristensen, Vessela N.; Tsalenko, Anya; Geisler, Jürgen; Faldaas, Anne; Grenaker, Grethe Irene; Lingjærde, Ole Christian; Fjeldstad, Ståle; Yakhini, Zohar; Lønning, Per Eystein; Børresen-Dale, Anne-Lise (BioMed Central, 2006-01-13)
    Background: Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing human geneticists ...
    Journal articlePeer reviewed
  • Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors 

    Klajic, Jovana; Fleischer, Thomas; Dejeux, Emelyne; Edvardsen, Hege; Warnberg, Fredrik; Bukholm, Ida Rashida Khan; Lønning, Per Eystein; Solvang, Hiroko Kato; Børresen-Dale, Anne-Lise; Tost, Jörg; Kristensen, Vessela N. (BioMed Central, 2013-10-05)
    Background: Aberrant DNA methylation of regulatory genes has frequently been found in human breast cancers and correlated to clinical outcome. In the present study we investigate stage specific changes in the DNA methylation ...
    Journal article