Now showing items 1-4 of 4

  • Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas 

    Fack, Fred; Espedal, Heidi; Keunen, Olivier; Golebiewska, Anna; Obad, Nina; Harter, Patrick N.; Mittelbronn, Michel; Bähr, Oliver; Weyerbrock, Astrid; Stuhr, Linda Elin Birkhaug; Miletic, Hrvoje; Sakariassen, Per Øystein; Stieber, Daniel; Rygh, Cecilie Brekke; Lund-Johansen, Morten; Zheng, Liang; Gottlieb, Eyal; Niclou, Simone P.; Bjerkvig, Rolf (Springer, 2015-01)
    Anti-angiogenic therapy in glioblastoma (GBM) has unfortunately not led to the anticipated improvement in patient prognosis. We here describe how human GBM adapts to bevacizumab treatment at the metabolic level. By performing ...
  • Gene expression profiling of meningiomas: current status after a decade of microarray-based transcriptomic studies 

    Aarhus, Mads; Lund-Johansen, Morten; Knappskog, Per (Springer, 2011-01-14)
    Purpose This article provides a review of the transcriptomic expression profiling studies that have been performed on meningiomas so far. We discuss some future prospects and challenges ahead in the field of gene ...
  • Microarray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts 

    Aarhus, Mads; Helland, Christian Andre; Lund-Johansen, Morten; Wester, Knut; Knappskog, Per (BioMed Central, 2010-02-26)
    Background Intracranial arachnoid cysts (AC) are membranous sacs filled with CSF-like fluid that are commonly found in the temporal fossa. The majority of ACs are congenital. Typical symptoms are headache, dizziness, and ...
  • Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies 

    Keunen, Olivier; Taxt, Torfinn; Grüner, Renate; Lund-Johansen, Morten; Tonn, Joerg-Christian; Pavlin, Tina; Bjerkvig, Rolf; Niclou, Simone P.; Thorsen, Frits Alan (Elsevier, 2014-09-30)
    The vastmajority ofmalignant gliomas relapse after surgery and standard radio-chemotherapy. Novelmolecular and cellular therapies are thus being developed, targeting specific aspects of tumor growth.While histopathology remains ...