Now showing items 1-2 of 2

  • Effekt av baseutkuttingsreparasjon på 5-formyluracil-indusert mutagenese 

    Østvoll, Martha (The University of Bergen, 2010-11-30)
    5-Formyluracil (fU) is an oxidation derivate of the DNA-base thymine. It can emerge in the organism by attack of reactive oxygen species, either endogenously or exogenously. Examples of exogenous agents are irradiaton or ...
  • KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer 

    Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B.; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Krakstad, Camilla; Salvesen, Helga B. (Cancer Research UK and Nature Publishing Group, 2012)
    BACKGROUND: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect from systemic therapies. Homo sapiens v-Ki-ras2 Kirsten rat ...