Now showing items 1-9 of 9

  • The cost of multiple sclerosis in Norway 

    Svendsen, Bjørn; Myhr, Kjell-Morten; Nyland, Harald Inge; Aarseth, Jan Harald (Springer, 2010-11-16)
    Health economic aspects have been increasingly important during introduction of new treatments for multiple sclerosis. As a partial response for Norway, a costof- illness study was carried out to estimate the yearly ...
  • Deficient phosphorylation of stat-1 in leukocytes identifies neutralizing antibodies in multiple sclerosis patients treated with interferon-beta 

    Gavasso, Sonia; Mosleth, Ellen Færgestad; Marøy, Tove Helene; Jørgensen, Katarina Mariann; Nakkestad, Hanne Linda; Gjertsen, Bjørn Tore; Myhr, Kjell-Morten; Vedeler, Christian A. (Public Library of Science, 2014-02-19)
    Background: Anti interferon-beta (IFN-β) neutralizing antibodies (NAb) affect efficacy of treatment of multiple sclerosis patients, but exactly when the detrimental effects of NAbs offset therapeutic efficacy is debated. ...
  • Dietary Vitamin D3 Supplements Reduce Demyelination in the Cuprizone Model 

    Wergeland, Stig; Torkildsen, Øivind; Myhr, Kjell-Morten; Aksnes, Lage; Mørk, Sverre; Bø, Lars (Public Library of Science, 2011-10-20)
    Vitamin D is emerging as a probably important environmental risk factor in multiple sclerosis, affecting both susceptibility and disease progression. It is not known to what extent this effect is due to a modulation of ...
  • Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome 

    Aasebø, Elise; Opsahl, Jill Anette; Bjørlykke, Yngvild; Myhr, Kjell-Morten; Kroksveen, Ann Cathrine; Berven, Frode S. (PLoS, 2014-03-05)
    Over the last years there has been an increased focus on the importance of knowing the effect of pre-analytical influence on the proteomes under study, particularly in the field of biomarker discovery. We present three ...
  • Employment among patients with multiple sclerosis - A population study 

    Lunde, Hanne Marie; Telstad, Wenche; Torkildsen, Nina Agnethe Grytten; Kyte, Lars; Aarseth, Jan; Myhr, Kjell-Morten; Bø, Lars (Public Library of Science, 2014-07-23)
  • Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort 

    Westerlind, Helga; Imrell, Kerstin; Ramanujam, Ryan; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Oturai, Annette Bang; Hamsten, Anders; Alfredsson, Lars; Olsson, Tomas; Kockum, Ingrid; Koski, Timo; Hillert, Jan (Nature Publishing Group, 2015)
    In an attempt to map chromosomal regions carrying rare gene variants contributing to the risk of multiple sclerosis (MS), we identified segments shared identical-by-descent (IBD) using the software BEAGLE 4.0’s refined IBD ...
  • Month of birth and risk of multiple sclerosis: confoundingand adjustments 

    Torkildsen, Øivind Fredvik; Aarseth, Jan Harald; Benjaminsen, Espen; Celius, Elisabeth Gulowsen; Holmøy, Trygve; Kampman, Margitta Theodora; Løken-Amsrud, Kristin Ingeleiv; Midgard, Rune; Myhr, Kjell-Morten; Riise, Trond; Torkildsen, Nina Agnethe Grytten (Wiley, 2014-02)
    A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place ...
  • mtDNA nt13708A Variant Increases the Risk of Multiple Sclerosis 

    Yu, Xinhua; Koczan, Dirk; Sulonen, Anna-Maija; Akkad, Denis A.; Kroner, Antje; Comabella, Manuel; Costa, Gianna; Corongiu, Daniela; Goertsches, Robert; Camina-Tato, Montserrat; Thiese, Hans-Juergen; Nyland, Harald Inge; Mørk, Sverre; Montalban, Xavier; Rieckmann, Peter; Marrosu, Maria G.; Myhr, Kjell-Morten; Epplen, Joerg T.; Saarela, Sanna; Ibrahim, Saleh M. (PLoS, 2008-02-13)
    Background: Mitochondrial DNA (mtDNA) polymorphism is a possible factor contributing to the maternal parent-of-origin effect in multiple sclerosis (MS) susceptibility. Methods and Findings: In order to investigate the ...
  • Poor Sleep in Patients with Multiple Sclerosis 

    Lunde, Hanne Marie Bøe; Aae, Tommy F.; Indrevåg, William; Aarseth, Jan Harald; Bjorvatn, Bjørn; Myhr, Kjell-Morten; Bø, Lars (Public Library of Science, 2012-11-14)
    Background: Poor sleep is a frequent symptom in patients with multiple sclerosis (MS). Sleep may be influenced by MS-related symptoms and adverse effects from immunotherapy and symptomatic medications. We aimed to study ...