Now showing items 1-2 of 2

  • Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-α-acetyltransferase 

    Arnesen, Thomas; Betts, Matthew J.; Pendino, Frédéric; Liberles, David A.; Anderson, Dave; Caro, Jaime; Kong, Xianguo; Varhaug, Jan Erik; Lillehaug, Johan (BioMed Central, 2006-04-25)
    Background: Protein acetylation is increasingly recognized as an important mechanism regulating a variety of cellular functions. Several human protein acetyltransferases have been characterized, most of them catalyzing ...
  • Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis 

    Gausdal, Gro; Wergeland, Anita; Skavland, Jørn; Nguyen, Eric; Pendino, Frédéric; Rouhee, Nazanin; McCormack, Emmet; Herfindal, Lars; Kleppe, Rune; Havemann, Ursula; Schwede, Frank; Bruserud, Øystein; Gjertsen, Bjørn Tore; Lanotte, Michel; Ségal-Bendirdjian, Evelyne; Døskeland, Stein Ove (Nature Publishing Group, 2013)
    We show that cyclic AMP (cAMP) elevating agents protect blasts from patients with acute promyelocytic leukemia (APL) against death induced by first-line anti-leukemic anthracyclines like daunorubicin (DNR). The cAMP effect ...