Now showing items 1-10 of 10

  • Age-dependent association between protein expression of the embryonic stem cell marker Cripto-1 and survival of glioblastoma patients 

    Tysnes, Berit Bølge; Sætran, Hege Aase; Mørk, Sverre; Margaryan, Naira v.; Eide, Geir Egil; Petersen, Kjell; Strizzi, Luigi; Hendrix, J. C. (Elsevier, 2013-12)
    Exploring the re-emergence of embryonic signaling pathways may reveal important information for cancer biology. Nodal is a transforming growth factor-β (TGF-β)-related morphogen that plays a critical role during embryonic ...
  • Data partitioning enables the use of standard SOAP Web Services in genome-scale workflows 

    Sztromwasser, Paweł; Puntervoll, Pål; Petersen, Kjell (IMBio e.V., 2011)
    Biological databases and computational biology tools are provided by research groups around the world, and made accessible on the Web. Combining these resources is a com- mon practice in bioinformatics, but integration ...
  • Direct data transfer between SOAP web services in Orchestration 

    Subramanian, Sattanathan; Sztromwasser, Paweł; Puntervoll, Pål; Petersen, Kjell (ACM, 2012)
    In scientific data analysis, workflows are used to integrate and coordinate resources such as databases and tools. Workflows are normally executed by an orchestrator that invokes component services and mediates data ...
  • Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation 

    Stansberg, Christine; Vik-Mo, Audun O.; Holdhus, Rita; Breilid, Harald; Srebro, Boleslaw; Petersen, Kjell; Jørgensen, Hugo A.; Jonassen, Inge; Steen, Vidar Martin (BioMed Central, 2007-04-04)
    Background: The mammalian brain is divided into distinct regions with structural and neurophysiological differences. As a result, gene expression is likely to vary between regions in relation to their cellular composition ...
  • Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L) 

    Tröße, Christiane; Waagbø, Rune; Breck, Olav; Stavrum, Anne-Kristin; Petersen, Kjell; Olsvik, Pål A. (Molecular Vision, 2009-07-09)
    Purpose: Elevated levels of dietary histidine have previously been shown to prevent or mitigate cataract formation in farmed Atlantic salmon (Salmo salar L). The aim of this study was to shed light on the mechanisms by ...
  • High-Throughput Mutation Profiling of Primary and Metastatic Endometrial Cancers Identifies KRAS, FGFR2 and PIK3CA to Be Frequently Mutated 

    Krakstad, Camilla; Birkeland, Even; Seidel, Danila; Kusonmano, Kanthida; Petersen, Kjell; Mjøs, Siv; Høivik, Erling Andre; Wik, Elisabeth; Halle, Mari Kyllesø; Øyan, Anne Margrete; Kalland, Karl-Henning; Werner, Henrica Maria Johanna; Trovik, Jone; Salvesen, Helga B. (Public Library of Science, 2012-12-27)
    Background: Despite being the most common pelvic gynecologic malignancy in industrialized countries, no targeted therapies are available for patients with metastatic endometrial carcinoma. In order to improve treatment, ...
  • The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice 

    Hjelmervik, Trond Ove R.; Linqvist, Anne-Karin; Petersen, Kjell; Johannesson, Martina; Stavrum, Anne-Kristin; Johansson, Åsa; Jonsson, Roland; Holmdahl, Rikard; Bolstad, Anne Isine (BioMed Central, 2007-09-27)
    The nonobese diabetic (NOD) Nss1 and Idd5 loci have been associated with sialadenitis development in mice. In this study the NOD Nss1 and Idd5 loci were backcrossed onto the healthy control strain B10.Q by using the ...
  • KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer 

    Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B.; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Krakstad, Camilla; Salvesen, Helga B. (Cancer Research UK and Nature Publishing Group, 2012)
    BACKGROUND: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect from systemic therapies. Homo sapiens v-Ki-ras2 Kirsten rat ...
  • A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB 

    Rayner, Tim F.; Rocca-Serra, Philippe; Spellman, Paul T.; Causton, Helen C.; Farne, Anna; Holloway, Ele; Irizarry, Rafael A.; Liu, Junmin; Maier, Donald S.; Miller, Michael; Petersen, Kjell; Quackenbush, John; Sherlock, Gavin; Stoeckert, Christian J. Jr; White, Joseph; Whetzel, Patricia L.; Wymore, Farrell; Parkinson, Helen; Sarkans, Ugis; Ball, Catherine A.; Brazma, Alvis (BioMed Central, 2006-11-06)
    Background: Sharing of microarray data within the research community has been greatly facilitated by the development of the disclosure and communication standards MIAME and MAGEML by the MGED Society. However, the ...
  • Switch in FOXA1 status associates with endometrial cancer progression 

    Tangen, Ingvild Løberg; Krakstad, Camilla; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Rodriguez, Antoni Hurtado; Salvesen, Helga Birgitte (Public Library of Science, 2014-05-21)
    Background: The transcription factor Forkhead box A1 (FOXA1) is suggested to be important in hormone dependent cancers, although with little data for endometrial cancer. We investigated expression levels of FOXA1 in primary ...