Now showing items 21-30 of 93
Stabilisation of Tyrosine Hydroxylase in Nanoparticles for Enzyme Replacement Therapy
(The University of Bergen, 2012-02-27)
The aim of this thesis has been to characterise nanoparticles (NPs) to which tyrosine hydroxylase (TH) was attached, as a preliminary step in their evaluation to be used for an enzyme replacement therapy (ERT) for ...
Development of a solid phase extraction method for evaluating the production of classic and nonclassic eicosanoids in human and fish cells using liquid chromatography tandem mass spectrometry
(The University of Bergen and National Institute of Nutrition and Seafood Research (NIFES), 2014-03-14)
Eicosanoids are the major metabolites of fatty acids and they are correlated with many kinds of diseases such as Alzheimer's, cancer and cardiovascular diseases. Usually, most of the eicosanoids derived from omega-6 fatty ...
Multivariate analysis and modeling of crude oil composition and fluid properties relevant for Multiphase Flow Metering
(The University of Bergen, 2014-09-05)
<p>Crude oil composition and properties have been subject for research for several decades, as well as the correlation between the chemical composition and physical properties of crude oil. The physical properties of crude ...
Towards a Synthesis of the Marine Alkaloid Naamidine B
(The University of Bergen, 2014-09-15)
Development and validation of a novel method for serotonin and 5-hydroxyindole-acetic acid determination in plasma using liquid chromatography tandem mass spectrometry
(The University of Bergen and University of Cadiz, 2014-05-07)
5-Hydroxytryptamine (5-HT) also known as serotonin is a biomarker in gastrointestinal disorder and several other pathological diseases where 5-HT and its metabolite 5-hydroxyindole-acetic acid are implicated. A sensitive ...
Investigation of serum protein profiles in scrapie infected sheep by means of SELDI-TOF-MS and multivariate data analysis
(BioMed Central Ltd., 2013-11-14)
<p><strong>Background:</strong> Classical scrapie in sheep is a fatal neurodegenerative disease associated with the conversion PrPC to PrPSc. Much is known about genetic susceptibility, uptake and dissemination of PrPSc ...
Online monitoring of an organic synthesis reaction using Raman and NIR spectroscopy
(The University of Bergen, 2011)
The synthesis of 10-Bromo-1-Decandiol was monitored using Raman and near infrared spectroscopy. Optical fiber Raman and near infrared probes were immersed in the reaction mixture. Raman spectra were recorded every ...
Quinolone-DNA interactions. Interactions and association between Ofloxacin and a DNA-oligomer studied by NMR methods
(The University of Bergen, 2003)
The first part of this thesis examines Ofloxacin (Oflo), a second-generation quinolone, by applying 1D 1H NMR. Molecular dynamics, stacking conditions and the self-diffusion constant were investigated. No certain ...
Kvantitativ analyse av biooljer fra Ltl-prosessen ved bruk av GC-FID
(The University of Bergen, 2015-02-12)
Etter hvert som energiressurser minker og klima endres, blir det nødvendig med en ny fornybar energikilde som ikke tilfører nytt CO2 til atmosfæren, er kompatibel med nåtidens bilmotorer, samt ikke konkurrerer med ...
Alkylfenolers innvirkning på glyserofosfolipidmembraner og kolesterol i torskehjerne
(The University of Bergen, 2003)
Oljeindustrien slipper ut store mengder produsert vann, som inneholder flere potensielle giftstoffer, blant annet alkylfenoler. Det ble tidlig vist at alkylfenoler kan ha skadelig virkning, særlig på grunn av østrogenhermende ...