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Factors accounting for the association between anxiety and depression, and eczema: the Hordaland health study (HUSK)

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dc.contributor.author Klokk, Marianne
dc.contributor.author Gotestam, Karl Gunnar
dc.contributor.author Mykletun, Arnstein
dc.date.accessioned 2011-04-26T08:26:31Z
dc.date.available 2011-04-26T08:26:31Z
dc.date.issued 2010-04-22
dc.identifier.citation BMC Dermatology 10:3 en_US
dc.identifier.issn 1471-5945
dc.identifier.uri http://dx.doi.org/10.1186/1471-5945-10-3
dc.identifier.uri http://hdl.handle.net/1956/4692
dc.description.abstract Background The association between anxiety and depression, and eczema is well known in the literature, but factors underlying this association remain unclear. Low levels of omega-3 fatty acids and female gender have been found to be associated with both depression and eczema. Somatization and health anxiety are known to be associated with anxiety and depression, further, somatization symptoms and health anxiety have also been found in several dermatological conditions. Accordingly, omega-3 fatty acid supplement, female gender, somatization and health anxiety are possible contributing factors in the association between anxiety and depression, and eczema. The aim of the study is to examine the relevance of proposed contributing factors for the association between anxiety and depression, and eczema, including, omega-3 fatty acid supplement, female gender, health anxiety and somatization. Methods Anxiety and depression was measured in the general population (n = 15715) employing the Hospital Anxiety and Depression Scale (HADS). Information on eczema, female gender, omega-3 fatty acid supplement, health anxiety and somatization was obtained by self-report. Results Somatization and health anxiety accounted for more than half of the association between anxiety/depression, and eczema, while the other factors examined were of minor relevance for the association of interest. Conclusions We found no support for female gender and omega-3 fatty acid supplement as contributing factors in the association between anxiety/depression, and eczema. Somatization and health anxiety accounted for about half of the association between anxiety/depression, and eczema, somatization contributed most. The association between anxiety/depression, and eczema was insignificant after adjustment for somatization and health anxiety. Biological mechanisms underlying the mediating effect of somatization are yet to be revealed. en_US
dc.language.iso eng en_US
dc.publisher BioMed Central en
dc.rights Copyright 2010 Klokk et al; licensee BioMed Central Ltd. en_US
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_US
dc.title Factors accounting for the association between anxiety and depression, and eczema: the Hordaland health study (HUSK) en_US
dc.type Peer reviewed en_US
dc.type Journal article en_US
dc.rightsHolder Klokk et al. en_US
dc.type.version publishedVersion en_US
bora.cristinID 340882


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Copyright 2010 Klokk et al; licensee BioMed Central Ltd. Except where otherwise noted, this item's license is described as Copyright 2010 Klokk et al; licensee BioMed Central Ltd.

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