Blar i Department of Biological Sciences på forfatter "Campsteijn, Coen"

Viser treff 1-6 av 6

    • Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics 

      Yadetie, Fekadu; Butcher, Stephen; Førde, Hilde E.; Campsteijn, Coen; Bouquet, Jean-Marie; Karlsen, Odd André; Denoeud, France; Metpally, Raghu; Thompson, Eric M.; Manak, J. Robert; Goksøyr, Anders; Chourrout, Daniel (Peer reviewed; Journal article, 2012-02-02)
      Background Animals have developed extensive mechanisms of response to xenobiotic chemical attacks. Although recent genome surveys have suggested a broad conservation of the chemical defensome across metazoans, global gene ...

    • Histone variant innovation in a rapidly evolving chordate lineage 

      Moosmann, Alexandra; Campsteijn, Coen; Jansen, Pascal W. T. C.; Nasrallah, Carole; Raasholm, Martina; Stunnenberg, Henk G; Thompson, Eric M. (Peer reviewed; Journal article, 2011-07-15)
      Background: Histone variants alter the composition of nucleosomes and play crucial roles in transcription, chromosome segregation, DNA repair, and sperm compaction. Modification of metazoan histone variant lineages occurs ...

    • Lifespan extension in a semelparous chordate occurs via developmental growth arrest just prior to meiotic entry 

      Subramaniam, Gunasekaran; Campsteijn, Coen; Thompson, Eric (Peer reviewed; Journal article, 2014-04-02)
      It is proposed that the ageing process is linked to signaling from the germline such that the rate of ageing can be adjusted to the state of the reproductive system, allowing these two processes to co-evolve. Mechanistic ...

    • OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica 

      Danks, Gemma Barbara; Campsteijn, Coen; Parida, Mruyunjaya; Butcher, Stephen; Doddapaneni, Harsha; Fu, Bolei; Petrin, Raul; Metpally, Raghu; Lenhard, Boris; Wincker, Patrick; Chourrout, Daniel; Thompson, Eric; Manak, J Robert (Peer reviewed; Journal article, 2013-11-26)
      We report the development of OikoBase (http://oikoarrays.biology.uiowa.edu/Oiko/), a tiling array-based genome browser resource for Oikopleura dioica, a metazoan belonging to the urochordates, the closest extant group to ...

    • Switching of INCENP paralogs controls transitions in mitotic chromosomal passenger complex functions 

      Feng, Haiyang; Raasholm, Martina; Moosmann-Schulmeister, Alexand; Campsteijn, Coen; Thompson, Eric (Peer reviewed; Journal article, 2019)
      A single inner centromere protein (INCENP) found throughout eukaryotes modulates Aurora B kinase activity and chromosomal passenger complex (CPC) localization, which is essential for timely mitotic progression. It has been ...

    • Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation 

      Vietri, Marina; Schultz, Sebastian; Bellanger, Aurélie Nathalie Pascale; Jones, Carl; Petersen, Louise I; Raiborg, Camilla; Skarpen, Ellen; Pedurupillay Jesuthasan, Christeen Ramane; Kjos, Ingrid; Kip, Eline; Timmer, Ronny; Jain, Ashish; Collas, Philippe; Knorr, Roland; Grellscheid, Sushma; Kusumaatmaja, Halim; Brech, Andreas; Micci, Francesca; Stenmark, Harald Alfred; Campsteijn, Coen (Journal article; Peer reviewed, 2020)
      The ESCRT-III membrane fission machinery maintains the integrity of the nuclear envelope. Although primary nuclei resealing takes minutes, micronuclear envelope ruptures seem to be irreversible. Instead, micronuclear ...