Blar i Department of Physics and Technology på forfatter "Pettersen, Helge Egil Seime"

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    • Characterization of monolithic CMOS pixel sensor chip with ion beams for application in particle computed tomography 

      Tambave, Ganesh Jagannath; Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; van den Brink, Anthony; Brons, Stephan; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Genov, Georgi; Grøttvik, Ola Slettevoll; Pettersen, Helge Egil Seime; Pastuović̀, Željko; Huiberts, Simon; Helstrup, Håvard; Hetland, Kristin Fanebust; Mehendale, Shruti Vineet; Meric, Ilker; Malik, Qasim Waheed; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Piersimoni, Pierluigi; Rehman, Attiq Ur; Reidt, Felix; Richter, Matthias; Røhrich, Dieter; Sudár, András; Samnøy, Andreas Tefre; Seco, Joao Carlos; Shafiee, Hesam; Skjæveland, Eivind Vågslid; Sølie, Jarle Rambo; Ullaland, Kjetil; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Yang, Shiming (Peer reviewed; Journal article, 2019)
      Particle computed tomography (pCT) is an emerging imaging modality that promises to reduce rangeuncertainty in particle therapy. The Bergen pCT collaboration aims to develop a novel pCT prototype basedon the ALPIDE monolithic ...

    • A Digital Tracking Calorimeter for Proton Computed Tomography 

      Pettersen, Helge Egil Seime (Doctoral thesis, 2018-05-29)
      Cancer is a destructive disease, in which tumor cells grow out-of-control, halting organ function. Its treatment is threefold: Radical surgery, chemotherapy and radiation therapy. Their relative usage is determined by ...

    • Enhancing Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer Patients with iCE, a Novel System for Automated Multi-Criterial Treatment Planning Including Beam Angle Optimization 

      Fjellanger, Kristine; Hysing, Liv Bolstad; Heijmen, Ben J.M.; Pettersen, Helge Egil Seime; Sandvik, Inger Marie; Sulen, Turid Husevåg; Breedveld, Sebastiaan; Rossi, Linda (Journal article; Peer reviewed, 2021)
      In this study, the novel iCE radiotherapy treatment planning system (TPS) for automated multi-criterial planning with integrated beam angle optimization (BAO) was developed, and applied to optimize organ at risk (OAR) ...

    • Helium radiography with a digital tracking calorimeter—a Monte Carlo study for secondary track rejection 

      Pettersen, Helge Egil Seime; Volz, Lennart; Sølie, Jarle Rambo; Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; van den Brink, Anthony; Borshchov, Vyacheslav; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Genov, Georgi; Grøttvik, Ola Slettevoll; Helstrup, Håvard; Keidel, Ralf; Kobdaj, Chinorat; van der Kolk, Naomi; Mehendale, Shruti Vineet; Meric, Ilker; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Piersimoni, Pierluigi; Protsenko, Maksym; Rehman, Attiq Ur; Richter, Matthias; Samnøy, Andreas Tefre; Seco, Joao; Shafiee, Hesam; Songmoolnak, Arnon; Tambave, Ganesh Jagannath; Tymchuk, Ihor; Ullaland, Kjetil; Varga-Kofarago, Monika; Wagner, Boris; Xiao, Renzheng; Yang, Shiming; Yokoyama, Hiroki; Röhrich, Dieter Rudolf Christian (Journal article; Peer reviewed, 2021)
      Radiation therapy using protons and heavier ions is a fast-growing therapeutic option for cancer patients. A clinical system for particle imaging in particle therapy would enable online patient position verification, ...

    • The Higgs Boson in Less Constrained Supersymmetric Models 

      Pettersen, Helge Egil Seime (Master thesis, 2012-06-01)
      In this thesis, we explore the phenomenological minimal supersymmetric standard model (pMSSM) in the context of the Higgs boson. If the emerging results from the LHC are real, will the pMSSM be able to accommodate this? ...

    • A high-granularity digital tracking calorimeter optimized for proton CT 

      Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; Borshchov, Vyacheslav; Bodova, Tea; van den Brink, Anthony; Brons, Stephan; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Feofilov, Grigory; Genov, Georgi; Grimstad, Silje; Grøttvik, Ola Slettevoll; Helstrup, Håvard; Herland, Alf Kristoffer; Hilde, Annar Eivindplass; Igolkin, Sergey; Keidel, Ralf; Kobdaj, Chinorat; van der Kolk, Naomi; Listratenko, Oleksandr; Malik, Qasim Waheed; Mehendale, Shruti Vineet; Meric, Ilker; Nesbø, Simon Voigt; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Pettersen, Helge Egil Seime; Piersimoni, Pierluigi; Protsenko, Maksym; Rehman, Attiq Ur; Richter, Matthias; Røhrich, Dieter; Samnøy, Andreas Tefre; Seco, Joao; Setterdahl, Lena; Shafiee, Hesam; Skjolddal, Øistein Jelmert; Solheim, Emilie Haugland; Songmoolnak, Arnon; Sudár, Ákos; Sølie, Jarle Rambo; Tambave, Ganesh Jagannath; Tymchuk, Ihor; Ullaland, Kjetil; Underdal, Håkon Andreas; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Widerøe, Fredrik Mekki; Xiao, RenZheng; Yang, Shiming; Yokoyama, Hiroki (Journal article; Peer reviewed, 2020)
      A typical proton CT (pCT) detector comprises a tracking system, used to measure the proton position before and after the imaged object, and an energy/range detector to measure the residual proton range after crossing the ...

    • A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy 

      Meric, Ilker; Alagoz, Enver; Hysing, Liv Bolstad; Kögler, Toni; Lathouwers, Danny; Lionheart, William R. B.; Mattingly, John; Obhodas, Jasmina; Pausch, Guntram; Pettersen, Helge Egil Seime; Ratliff, Hunter Nathaniel; Rovituso, Marta; Schellhammer, Sonja M.; Setterdahl, Lena Marie; Skjerdal, Kyrre; Sterpin, Edmond; Sudac, Davorin; Turko, Joseph A.; Ytre-Hauge, Kristian Smeland (Journal article; Peer reviewed, 2023)
      Particle therapy (PT) used for cancer treatment can spare healthy tissue and reduce treatment toxicity. However, full exploitation of the dosimetric advantages of PT is not yet possible due to range uncertainties, warranting ...

    • Image quality of list-mode proton imaging without front trackers 

      Sølie, Jarle Rambo; Volz, Lennart; Pettersen, Helge Egil Seime; Piersimoni, Pierluigi; Odland, Odd Harald; Røhrich, Dieter; Helstrup, Håvard; Peitzmann, Thomas; Ullaland, Kjetil; Varga-Kofarago, Monika; Mehendale, Shruti Vineet; Grøttvik, Ola Slettevoll; Eikeland, Viljar Nilsen; Meric, Ilker; Seco, Joao (Journal article; Peer reviewed, 2020)
      List mode proton imaging relies on accurate reconstruction of the proton most likely path (MLP) through the patient. This typically requires two sets of position sensitive detector systems, one upstream (front) and one ...

    • Improving knowledge-based treatment planning for lung cancer radiotherapy with automatic multi-criteria optimized training plans 

      Fjellanger, Kristine; Hordnes, Marte; Sandvik, Inger Marie; Sulen, Turid Husevåg; Heijmen, Ben J. M.; Breedveld, Sebastiaan; Rossi, Linda; Pettersen, Helge Egil Seime; Hysing, Liv Bolstad (Journal article; Peer reviewed, 2023)
      Background: Knowledge-based planning (KBP) is a method for automated radiotherapy treatment planning where appropriate optimization objectives for new patients are predicted based on a library of training plans. KBP can ...

    • In-situ measurements of rare earth elements in deep sea sediments using nuclear methods 

      Obhođaš, Jasmina; Sudac, Davorin; Meric, Ilker; Pettersen, Helge Egil Seime; Uroić, Milivoj; Nađ, Karlo; Valković, Vlado (Peer reviewed; Journal article, 2018-03-21)
      The prospecting activities for finding new rare earth elements (REE) sources have increased greatly in recent years. One of the main discoveries was announced in 2011 by Japanese researchers who found large quantities of ...

    • Linear energy transfer-inclusive models of brainstem necrosis following proton therapy of paediatric ependymoma 

      Handeland, Andreas Havsgård; Indelicato, Daniel J.; Fjæra, Lars Fredrik; Ytre-Hauge, Kristian Smeland; Pettersen, Helge Egil Seime; Muren, Ludvig Paul; Lassen-Ramshad, Yasmin; Stokkevåg, Camilla Hanquist (Journal article; Peer reviewed, 2023)
      Background and Purpose Radiation-induced brainstem necrosis after proton therapy is a severe toxicity with potential association to uncertainties in the proton relative biological effectiveness (RBE). A constant RBE of ...

    • Patient selection, inter-fraction plan robustness and reduction of toxicity risk with deep inspiration breath hold in intensity-modulated radiotherapy of locally advanced non-small cell lung cancer 

      Fjellanger, Kristine; Rossi, Linda; Heijmen, Ben J.M.; Pettersen, Helge Egil Seime; Sandvik, Inger Marie; Breedveld, Sebastiaan; Sulen, Turid Husevåg; Hysing, Liv Bolstad (Journal article; Peer reviewed, 2022)
      Background: State-of-the-art radiotherapy of locally advanced non-small cell lung cancer (LA-NSCLC) is performed with intensity-modulation during free breathing (FB). Previous studies have found encouraging geometric ...

    • Toward the end-to-end optimization of particle physics instruments with differentiable programming 

      Dorigo, Tommaso; Giammanco, Andrea; Vischia, Pietro; Aehle, Max; Bawaj, Mateusz; Boldyrev, Alexey; de Castro Manzano, Pablo; Derkach, Denis; Donini, Julien; Edelen, Auralee; Fanzago, Federica; Gauger, Nicolas R.; Glaser, Christian; Baydin, Atılım G.; Heinrich, Lukas; Keidel, Ralf; Kieseler, Jan; Krause, Claudius; Lagrange, Maxime; Lamparth, Max; Layer, Lukas; Maier, Gernot; Nardi, Federico; Pettersen, Helge Egil Seime; Ramos, Alberto; Ratnikov, Fedor; Röhrich, Dieter; de Austri, Roberto Ruiz; del Árbol, Pablo Martínez Ruiz; Savchenko, Oleg; Simpson, Nathan; Strong, Giles C.; Taliercio, Angela; Tosi, Mia; Ustyuzhanin, Andrey; Zaraket, Haitham (Journal article; Peer reviewed, 2023)
      The full optimization of the design and operation of instruments whose functioning relies on the interaction of radiation with matter is a super-human task, due to the large dimensionality of the space of possible choices ...

    • Towards Neural Charged Particle Tracking in Digital Tracking Calorimeters With Reinforcement Learning 

      Kortus, Tobias; Keidel, Ralf; Gauger, Nicolas R.; Aehle, Max; Alme, Johan; Barnaföldi, Gergely Gábor; Bodova, Tea; Borshchov, Vyacheslav; Vanden Brink, Anthony; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Feofilov, Gregory; Garth, Christoph; Genov, Georgi Yordanov; Grøttvik, Ola Slettevoll; Helstrup, Håvard; Igolkin, Sergey; Kobdaj, Chinorat; Leonhardt, Viktor; Mehendale, Shruti Vineet; Mulawade, Raju Ningappa; Odland, Odd Harald; O'Neill, George; Papp, Gabor; Peitzmann, Thomas; Pettersen, Helge Egil Seime; Piersimoni, Pierluigi; Protsenko, Maksym; Rauch, Max Philip; Rehman, Attiq Ur; Richter, Matthias; Röhrich, Dieter Rudolf Christian; Santana, Joshua; Schilling, Alexander; Seco, Joao; Songmoolnak, Arnon; Sudár, Ákos; Salie, Jarle Rambo; Tambave, Ganesh Jagannath; Tymchuk, Ihor; Ullaland, Kjetil; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Wendzel, Steffen; Wiebel, Alexander; Xiao, Renzheng; Yang, Shiming; Yokoyama, Hiroki; Zillien, Sebastian (Journal article; Peer reviewed, 2023)
      We propose a novel technique for reconstructing charged particles in digital tracking calorimeters using reinforcement learning aiming to benefit from the rapid progress and success of neural network architectures without ...

    • Uncertainty-aware spot rejection rate as quality metric for proton therapy using a digital tracking calorimeter 

      Schilling, Alexander; Aehle, Max; Alme, Johan; Barnaföldi, Gergely Gábor; Bodova, Tea; Borshchov, Vyacheslav; van den Brink, Anthony; Eikeland, Viljar Nilsen; Feofilov, Gregory; Garth, Christoph; Gauger, Nicolas R.; Grøttvik, Ola Slettevoll; Helstrup, Håvard; Igolkin, Sergey; Keidel, Ralf; Kobdaj, Chinorat; Kortus, Tobias; Leonhardt, Viktor; Mehendale, Shruti Vineet; Ningappa Mulawade, Raju; Odland, Odd Harald; O'Neill, George; Papp, Gábor; Peitzmann, Thomas; Pettersen, Helge Egil Seime; Piersimoni, Pierluigi; Protsenko, Maksym; Rauch, Max Philip; Rehman, Attiq Ur; Richter, Matthias; Röhrich, Dieter; Santana, Joshua; Seco, Joao; Songmoolnak, Arnon; Sudár, Ákos; Tambave, Ganesh Jagannath; Tymchuk, Ihor; Ullaland, Kjetil; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Wendzel, Steffen; Wiebel, Alexander; Xiao, Renzheng; Yang, Shiming; Zillien, Sebastian (Journal article; Peer reviewed, 2023)
      Objective. Proton therapy is highly sensitive to range uncertainties due to the nature of the dose deposition of charged particles. To ensure treatment quality, range verification methods can be used to verify that the ...

    • Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors 

      Otterlei, Ole Marius; Indelicato, Daniel J.; Toussaint, Laura; Ytre-Hauge, Kristian; Pilskog, Sara; Fjæra, Lars Fredrik; Rørvik, Eivind; Pettersen, Helge Egil Seime; Muren, Ludvig Paul; Lassen-Ramshad, Yasmin; Di Pinto, Marcos; Stokkevåg, Camilla Hanquist (Journal article; Peer reviewed, 2021)
      Background Clinically, a constant value of 1.1 is used for the relative biological effectiveness (RBE) of protons, whereas in vitro the RBE has been shown to vary depending on physical dose, tissue type, and linear energy ...