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    • Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population 

      Estrada, Karol; Aukrust, Ingvild; Bjørkhaug, Lise; Najmi, Laeya Abdoli; Njølstad, Pål Rasmus; MacArthur, Daniel G.; The SIGMA Type 2 Diabetes Consortium (Peer reviewed; Journal article, 2014-06)
      Importance: Latino populations have one of the highest prevalences of type 2 diabetes worldwide. Objectives: To investigate the association between rare protein-coding genetic variants and prevalence of type 2 diabetes in ...

    • Association of adult lung function with accelerated biological aging 

      Rezwan, Faizal I; Imboden, Medea; Amaral, André F.S.; Wielscher, Matthias; Jeong, Ayoung; Triebner, Kai; Gomez Real, Francisco; Jarvelin, Marjo-Riitta; Jarvis, Deborah; Probst-Hensch, Nicole M; Holloway, John W (Journal article; Peer reviewed, 2020)
      Lung function, strongly associated with morbidity and mortality, decreases with age. This study examines whether poor adult lung function is associated with age accelerations (AAs). DNA methylation (DNAm) based AAs, lifespan ...

    • Association of adverse childhood experiences with the development of multiple sclerosis 

      Eid, Karine; Torkildsen, Øivind; Aarseth, Jan Harald; Aalstad, Mari; Bhan, Alok; Celius, Elisabeth Gulowsen; Cortese, Marianna; Daltveit, Anne Kjersti Nesje; Holmøy, Trygve; Myhr, Kjell-Morten; Riise, Trond; Schuler, Stephan; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Objective To study whether exposure to childhood emotional, sexual or physical abuse is associated with subsequent multiple sclerosis (MS) development. Methods A nationwide, prospective cohort study based on participants ...

    • Association of autoimmune Addison's disease with alleles of STAT4 and GATA3 in European Cohorts 

      Mitchell, Anna L.; Macarthur, Katie D.R.; Gan, Earn H.; Baggott, Lucy E.; Wolff, Anette Susanne Bøe; Skinningsrud, Beate; Platt, Hazel; Short, Andrea; Lobell, Anna; Kämpe, Olle; Bensing, Sophie; Betterle, Corrado; Kasperlik-Zaluska, Anna; Zurawek, Magdalena; Fichna, Marta; Kockum, Ingrid; Eriksson, Gabriel Nordling; Ekwall, Olov; Wahlberg, Jeanette; Dahlqvist, Per; Hulting, Anna-Lena; Penna-Martinez, Marissa; Meyer, Gesine; Kahles, Heinrich; Badenhoop, Klaus; Hahner, Stefanie; Quinkler, Marcus; Falorni, Alberto; Phipps-Green, Amanda; Merriman, Tony R.; Ollier, William; Cordell, Heather J.; Undlien, Dag Erik; Czarnocka, Barbara; Husebye, Eystein Sverre; Pearce, Simon H.S. (Peer reviewed; Journal article, 2014-03-10)
      Background: Gene variants known to contribute to Autoimmune Addison's disease (AAD) susceptibility include those at the MHC, MICA, CIITA, CTLA4, PTPN22, CYP27B1, NLRP-1 and CD274 loci. The majority of the genetic component ...

    • Association of body mass index with risk of acute myocardial infarction and mortality in Norwegian male and female patients with suspected stable angina pectoris: a prospective cohort study 

      Borgeraas, Heidi; Hertel, Jens Kristoffer; Svingen, Gard Frodahl Tveitevåg; Seifert, Reinhard; Pedersen, Eva Kristine Ringdal; Schartum-Hansen, Hall; Hjelmesæth, Jøran; Nygård, Ottar (Peer reviewed; Journal article, 2014-05-21)
      Background: A number of previous studies have suggested that overweight or obese patients with coronary artery disease (CAD) may have lower morbidity and mortality than their leaner counterparts. Few studies have addressed ...

    • The association of child marriage with morbidities and mortality among children under 5 years in Afghanistan: findings from a national survey 

      Dadras, Omid; Hazratzai, Mohammadsediq; Dadras, Fateme (Journal article; Peer reviewed, 2023)
      Background There is still a gap in knowledge of the impact that child marriage could have on the mortality and morbidity of children in Afghanistan. This study used the data from the latest Afghanistan demographic health ...

    • An Association of Chitinase-3 Like-Protein-1 With Neuronal Deterioration in Multiple Sclerosis 

      Ahmad, Intakhar; Wergeland, Stig; Oveland, Eystein; Bø, Lars (Journal article; Peer reviewed, 2023)
      Elevated levels of Chitinase-3-like protein-1 (CHI3L1) in cerebrospinal fluid have previously been linked to inflammatory activity and disease progression in multiple sclerosis (MS) patients. This study aimed to investigate ...

    • Association of chronic heart failure with mortality in old intensive care patients suffering from Covid-19 

      Bruno, Raphael Romano; Wernly, Bernhard; Wolff, Georg; Fjølner, Jesper; Artigas, Antonio; Bollen Pinto, Bernardo; Schefold, Joerg C.; Kindgen-Milles, Detlef; Baldia, Philipp Heinrich; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Topeli, Arzu; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Kondili, Eumorfia; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian; Jung, Christian (Journal article; Peer reviewed, 2022)
      Aims Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID-19). This prospective international multicentre study investigates the role of pre-existing CHF on clinical outcomes ...

    • Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease 

      Oftedal, Linn Silje Wathne; Maple-Grødem, Jodi; Dalen, Ingvild; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes (Journal article; Peer reviewed, 2022)
      Background and Objectives Variations in the glucocerebrosidase gene (GBA) are common risk factors for Parkinson disease (PD) and dementia in PD (PDD) and cause a reduction in the activity of the lysosomal enzyme ...

    • Association of CYP2D6 genotype and tamoxifen metabolites with breast cancer recurrence in a low-dose trial 

      DeCensi, Andrea; Johansson, Harriet; Helland, Thomas; Puntoni, Matteo; Macis, Debora; Aristarco, Valentina; Caviglia, Silvia; Webber, Tania Buttiron; Briata, Irene Maria; D’Amico, Mauro; Serrano, Davide; Guerrieri-Gonzaga, Aliana; Bifulco, Ersilia; Hustad, Simon Steinar; Søiland, Håvard; Boni, Luca; Bonanni, Bernardo; Mellgren, Gunnar (Journal article; Peer reviewed, 2021)
      Low-dose tamoxifen halves recurrence in non-invasive breast cancer without significant adverse events. Some adjuvant trials with tamoxifen 20 mg/day had shown an association between low endoxifen levels (9–16 nM) and ...

    • Association of Delayed Surgery for Ankle Fractures and Patient-Reported Outcomes 

      Pilskog, Kristian; Gote, Teresa Brnic; Odland, Heid Elin Johannesen; Fjeldsgaard, Knut; Dale, Håvard; Inderhaug, Eivind; Fevang, Jonas Meling (Journal article; Peer reviewed, 2022)
      Background: Several studies probe the association between prolonged time to surgery and postoperative complications in ankle fractures, but little is known about how a longer wait time affects clinical outcomes. The present ...

    • The association of dietary patterns with muscle mass and strength in old age: The Hordaland Health Study 

      Sabir, Zoya; Dierkes, Jutta; Hjartåker, Anette; Rosendahl-Riise, Hanne (Journal article; Peer reviewed, 2023)
      Purpose: The single nutrient approach in nutrition research lacks the ability to account for synergistic relationships between dietary components. Current evidence suggests that diet quality, reflecting overall dietary ...

    • Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort 

      Haugsgjerd, Teresa Risan; Egeland, Grace M.; Nygård, Ottar; Vinknes, Kathrine; Sulo, Gerhard; Lysne, Vegard; Igland, Jannicke; Tell, Grethe S. (Journal article; Peer reviewed, 2020)
      Objective: The role of vitamin K in the regulation of vascular calcification is established. However, the association of dietary vitamins K1 and K2 with risk of coronary heart disease (CHD) is inconclusive. Design: ...

    • The association of electronic health literacy with behavioural and psychological coronary artery disease risk factors in patients after percutaneous coronary intervention: a 12-month follow-up study 

      Brørs, Gunhild; Dalen, Håvard; Allore, Heather; Deaton, Christi; Fridlund, Bengt Gotthard Anton; Norman, Cameron D.; Palm, Pernille; Wentzel-Larsen, Tore; Norekvål, Tone Merete (Journal article; Peer reviewed, 2023)
      Aims Fundamental roadblocks, such as non-use and low electronic health (eHealth) literacy, prevent the implementation of eHealth resources. The aims were to study internet usage for health information and eHealth literacy ...

    • Association of Excessive Sleepiness, Pathological Fatigue, Depression, and Anxiety With Different Severity Levels of Obstructive Sleep Apnea 

      Mjelle, Karin Elisabeth Sundt; Lehmann, Sverre; Saxvig, Ingvild W.; Gulati, Shashi; Bjorvatn, Bjørn (Journal article; Peer reviewed, 2022-03-31)
      Objective: The aim of this study was to investigate possible associations between obstructive sleep apnea and fatigue. This naturally led to considering the association between OSA and excessive sleepiness, depression, and ...

    • Association of Familial Hypercholesterolemia and Statin Use With Risk of Dementia in Norway 

      Mundal, Liv; Igland, Jannicke; Svendsen, Karianne; Holven, Kirsten Bjørklund; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Peer reviewed, 2022)
      Importance Hypercholesterolemia, which is a cardiovascular risk factor, may also be associated with dementia risk. The benefit of statin treatment on dementia risk is controversial. Objective To determine whether ...

    • Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies 

      Hansen, Kim Wadt; Peytz, Nina; Blokstra, Anneke; Bojesen, Stig E.; Celis-Morales, Carlos; Chrysohoou, Christina; Clays, Els; De Bacquer, Dirk; Galatius, Søren; Gray, Stuart R.; Ho, Frederick; Kavousi, Maryam; Koolhaas, Chantal M.; Kouvari, Matina; Løchen, Maja-Lisa; Marques-Vidal, Pedro; Osler, Merete; Panagiotakos, Demosthenes; Pell, Jill P.; Sulo, Gerhard; Tell, Grethe Seppola; Vassiliou, Vassilios; Verschuren, W.M. Monique; Prescott, Eva (Journal article; Peer reviewed, 2021)
      Aims To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies. Methods and results European ...

    • Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease 

      Grødem, Jodi Maple; Dalen, Ingvild; Tysnes, Ole-Bjørn; Macleod, Angus D.; Forsgren, Lars; Counsell, Carl E.; Alves, Guido Werner (Journal article; Peer reviewed, 2021)
      Objective To establish the significance of glucocerebrosidase gene (GBA) carrier status on motor impairment in a large cohort of patients with incident Parkinson disease (PD). Methods Three European population-based ...

    • Association of gender to outcome after out-of-hospital cardiac arrest - a report from the International Cardiac Arrest Registry 

      Karlsson, Viktor; Dankiewicz, Josef; Nielsen, Niklas; Kern, Karl B.; Mooney, Michael R.; Riker, Richard R.; Rubertsson, Sten; Seder, David B.; Stammet, Pascal; Sunde, Kjetil; Søreide, Eldar; Unger, Barbara T.; Friberg, Hans (Peer reviewed; Journal article, 2015-04-21)
      Introduction Previous studies have suggested an effect of gender on outcome after out-of-hospital cardiac arrest (OHCA), but the results are conflicting. We aimed to investigate the association of gender to outcome, coronary ...

    • The Association of Gum Bleeding with Respiratory Health in a Population Based Study from Northern Europe 

      Gomez, Francisco; Barrionuevo, Laura Perez; Franklin, K.; Lindberg, E.; Bertelsen, Randi Jacobsen; Benediktsdottir, Bryndis; Forsberg, B; Gislason, T; Jøgi, Rain; Johannessen, Ane; Omenaas, Ernst; Saure, Eirunn Waatevik; Schlunssen, V.; Skorge, Trude Duelien; Toren, Kjell; Saavedra, A; Svanes, Øistein; Åstrøm, Anne Nordrehaug; Janson, Christer; Svanes, Cecilie (Peer reviewed; Journal article, 2016-01-25)
      Background: There is little knowledge about how oral and respiratory health is interrelated even though the mucosa of the oral cavity and airways constitutes a continuum and the exposures to these are partly similar. Aims: ...