• Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children 

      Ueland, Grethe Åstrøm; Kellmann, Ralf; Davidsen, Melissa Jørstad; Viste, Kristin; Husebye, Eystein Sverre; Almås, Bjørg; Storr, Helen L.; Sagen, Jørn Vegard; Mellgren, Gunnar; Juliusson, Pétur Benedikt; Methlie, Paal (Journal article; Peer reviewed, 2021)
      Background Diagnosing Cushing syndrome (CS) can be challenging. The 24-hour urine free cortisol (UFC) measurement is considered gold standard. This is a laborious test, dependent on correct urine collection. Late-night ...
    • Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling 

      Forsse, David Erik; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Viste, Kristin; Almås, Bjørg; Bertelsen, Bjørn-Erik; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Peer reviewed; Journal article, 2020-02)
      Objective Blood-based biomarkers are attractive due to ease of sampling and standardized measurement technology, reducing obstacles to clinical implementation. The objective of this study was to evaluate a clinically ...
    • Efficacy of adrenal venous sampling is increased by point of care cortisol analysis 

      Viste, Kristin; Grytaas, Marianne Aardal; Jørstad, Melissa; Jøssang, Dag Eirik; Høyden, Eivind Næss; Fotland, Solveig Simmenes; Jensen, Dag Kjartan; Løvås, Kristian; Thordarson, Hrafnkell B; Almås, Bjørg; Mellgren, Gunnar (Peer reviewed; Journal article, 2013)
      Primary aldosteronism (PA) is a common cause of secondary hypertension and is caused by unilateral or bilateral adrenal disease. Treatment options depend on whether the disease is lateralized or not, which is preferably ...
    • Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty 

      Madsen, Andre; Bruserud, Ingvild Særvold; Bertelsen, Bjørn-Erik; Roelants, Mathieu; Oehme, Ninnie; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Petur Benedikt (Journal article; Peer reviewed, 2020)
      Context Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement ...
    • Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison’s disease 

      Methlie, Paal; Hustad, Simon Steinar; Kellmann, Ralph; Almås, Bjørg; Moter-Erichsen, M; Husebye, ES; Løvås, Kristian (Peer reviewed; Journal article, 2013)
      Objective: Liquid chromatography–tandem mass spectrometry (LC–MS/MS) offers superior analytical specificity compared with immunoassays, but it is not available in many regions and hospitals due to expensive instrumentation ...
    • Primary Hyperparathyroidism Influences the Expression of Inflammatory and Metabolic Genes in Adipose Tissue 

      Christensen, Monika H. E.; Dankel, Simon N; Nordbø, Yngve; Varhaug, Jan Erik; Almås, Bjørg; Lien, Ernst Asbjørn; Mellgren, Gunnar (Peer reviewed; Journal article, 2011-06-17)
      Background: Primary hyperparathyroidism (PHPT) is characterised by increased production of parathyroid hormone (PTH) resulting in elevated serum calcium levels. The influence on bone metabolism with altered bone resorption ...
    • Reference curves for pediatric endocrinology: leveraging biomarker z-scores for clinical classifications 

      Madsen, Andre; Almås, Bjørg; Bruserud, Ingvild Særvold; Oehme, Ninnie Helen Bakken; Nielsen, Christopher Sivert; Roelants, Mathieu; Hundhausen, Thomas Eckhard; Ljubicic, Marie Lindhardt; Bjerknes, Robert; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Pétur Benedikt; Viste, Kristin (Journal article; Peer reviewed, 2022)
      Context Hormone reference intervals in pediatric endocrinology are traditionally partitioned by age and lack the framework for benchmarking individual blood test results as normalized z-scores and plotting sequential ...
    • Simultaneous Quantification of Aromatase Inhibitors and Estrogens in Postmenopausal Breast Cancer Patients 

      Bertelsen, Bjørn-Erik; Viste, Kristin; Helland, Thomas; Hagland, Magnus; Søiland, Håvard; Geisler, Jürgen; Lende, Tone Hoel; Lønning, Per Eystein; Sagen, Jørn Vegard; Mellgren, Gunnar; Almås, Bjørg (Journal article; Peer reviewed, 2021)
      Context Currently there are no assays that can simultaneously quantify serum levels of the third-generation aromatase inhibitors (AIs): letrozole, anastrozole, and exemestane, and the ultra-low levels of estrogens in ...
    • Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty 

      Madsen, Andre; Oehme, Ninnie; Roelants, Mathieu; Bruserud, Ingvild Særvold; Eide, Geir Egil; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Sagen, Jørn V.; Mellgren, Gunnar; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2020)
      Context: Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based on chronological age and subjective assessments of discrete puberty development ...