Blar i Faculty of Medicine på forfatter "Basnet, Sudha"
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25-hydroxy-vitamin D concentration is not affected by severe or non-severe pneumonia, or inflammation, in young children
Haugen, Johanne; Chandyo, Ram Krishna; Ulak, Manjeswori; Mathisen, Maria; Basnet, Sudha; Brokstad, Karl Albert; Valentiner-Branth, Palle; Shrestha, Prakash S.; Strand, Tor A (Peer reviewed; Journal article, 2017-01-17)Poor vitamin D status has been associated with increased risk and severity of respiratory tract infections. Whether or not inflammation and infection affects 25-hydroxy vitamin D (25(OH)D) concentration is controversial ... -
Acute Lower Respiratory Infection in Childhood and Household Fuel Use in Bhaktapur, Nepal
Bates, Michael N.; Chandyo, Ram Krishna; Valentiner-Branth, Palle; Pokhrel, Amod K.; Mathisen, Maria; Basnet, Sudha; Shrestha, Prakash S.; Strand, Tor A.; Smith, Kirk R. (Peer reviewed; Journal article, 2013-05)Background: Globally, solid fuels are used by about 3 billion people for cooking. These fuels have been associated with many health effects, including acute lower respiratory infection (ALRI) in young children. Nepal has ... -
An analysis of clinical predictive values for radiographic pneumonia in children
Rees, Chris A; Basnet, Sudha; Gentile, Angela; Gessner, Bradford D; Kartasasmita, Cissy B.; Lucero, Marilla G.; Martinez, Luis Moreno; O'Grady, Kerry-Ann F; Ruvinsky, Raul O; Turner, Claudia; Campbell, Harry; Nair, Harish; Falconer, Jennifer; Williams, Linda J.; Horne, Margaret; Strand, Tor A; Nisar, Yasir B; Qazi, Shamim A; Neuman, Mark I (Journal article; Peer reviewed, 2020)Abstract Introduction Healthcare providers in resource-limited settings rely on the presence of tachypnoea and chest indrawing to establish a diagnosis of pneumonia in children. We aimed to determine the test characteristics ... -
Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: Methodology and applications
Martin, Helena; Falconer, Jennifer; Addo-Yobo, Emmanuel; Aneja, Satinder; Arroyo, Luis Martinez; Asghar, Rai; Awasthi, Shally; Banajeh, Salem; Bari, Abdul; Basnet, Sudha; Bavdekar, Ashish; Bhandari, Nita; Bhatnagar, Shinjini; Bhutta, Zulfiqar A.; Brooks, Abdullah; Chadha, Mandeep; Chisaka, Noel; Chou, Monidarin; Clara, Alexey W.; Colbourn, Tim; Cutland, Clare; D'Acremont, Valérie; Echavarria, Marcela; Gentile, Angela; Gessner, Brad; Gregory, Christopher J.; Hazir, Tabish; Hibberd, Patricia L.; Hirve, Siddhivinayak; Hooli, Shubhada; Iqbal, Imran; Jeena, Prakash; Kartasasmita, Cissy B.; King, Carina; Libster, Romina; Lodha, Rakesh; Lozano, Juan M.; Lucero, Marilla; Lufesi, Norman; MacLeod, William B.; Madhi, Shabir Ahmed; Mathew, Joseph L.; Maulen-Radovan, Irene; McCollum, Eric D.; Mino, Greta; Mwansambo, Charles; Neuman, Mark I.; Nguyen, Ngoc Tuong Vy; Nunes, Marta C.; Nymadawa, Pagbajabyn; O'Grady, Kerry-Ann F; Pape, Jean-William; Paranhos-Baccala, Glaucia; Patel, Archana; Picot, Valentina Sanchez; Rakoto-Andrianarivelo, Mala; Rasmussen, Zeba; Rouzier, Vanessa; Russomando, Graciela; Ruvinsky, Raul O.; Sadruddin, Salim; Saha, Samir K.; Santosham, Mathuram; Singhi, Sunit; Soofi, Sajid; Strand, Tor Arne; Sylla, Mariam; Thamthitiwat, Somsak; Thea, Donald M.; Turner, Claudia; Vanhems, Philippe; Wadhwa, Nitya; Wang, Jianwei; Zaman, Syed Ma; Campbell, Harry; Nair, Harish; Qazi, Shamim Ahmad; Nisar, Yasir Bin (Journal article; Peer reviewed, 2022)Background The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed ... -
Assessment of hospitalization costs and its determinants in infants with clinical severe infection at a public tertiary hospital in Nepal
Shrestha, Suchita; Chapagain, Ram Hari; Purakayastha, Debjani Ram; Basnet, Srijana; Wadhwa, Nitya; Strand, Tor Arne; Basnet, Sudha (Journal article; Peer reviewed, 2021)Sepsis, an important and preventable cause of death in the newborn, is associated with high out of pocket hospitalization costs for the parents/guardians. The government of Nepal’s Free Newborn Care (FNC) service that ... -
Cytokine concentrations in plasma from children with severe and non-severe community acquired pneumonia
Haugen, Johanne; Chandyo, Ram Krishna; Brokstad, Karl Albert; Mathisen, Maria; Ulak, Manjeswori; Basnet, Sudha; Valentiner-Branth, Palle; Strand, Tor (Journal article; Peer reviewed, 2015-09-25)Background: Children in low and middle-income countries have a high burden of pneumonia. Measuring the cytokine responses may be useful to identify novel markers for diagnosing, monitoring, and treating pneumonia. Objective: ... -
The effect of infant vitamin B12 supplementation on neurodevelopment: A follow-up of a randomized placebo-controlled trial in Nepal
Chandyo, Manjeswori Ulak; Kvestad, Ingrid; Chandyo, Ram Krishna; Ranjitkar, Suman; Hysing, Mari; Schwinger, Catherine; Shrestha, Merina; Basnet, Sudha; Shrestha, Laxman; Strand, Tor Arne (Journal article; Peer reviewed, 2022)The most critical period for brain development is before a child’s second birthday. Standardised tests measuring neurodevelopment are more reliable when administered after this period. Severe vitamin B12 deficiency affects ... -
The effects of vitamin B12 supplementation in pregnancy and postpartum on growth and neurodevelopment in early childhood: Study Protocol for a Randomized Placebo Controlled Trial
Chandyo, Ram Krishna; Ulak, Manjeswori; Kvestad, Ingrid; Shrestha, Merina; Ranjitkar, Suman; Basnet, Sudha; Hysing, Mari; Shrestha, Laxman; Strand, Tor A (Peer reviewed; Journal article, 2017)Introduction: Vitamin B12 is crucial for normal cell division and differentiation, and necessary for the development and myelination of the central nervous system. Pregnant mothers in resource poor settings are at risk for ... -
External validation of the RISC, RISC-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia
Rees, Chris A.; Hooli, Shubhada; King, Carina; McCollum, Eric D.; Colbourn, Tim; Lufesi, Norman; Mwansambo, Charles; Lazzerini, Marzia; Madhi, Shabir A.; Cutland, Clare; Nunes, Marta; Gessner, Bradford D.; Basnet, Sudha; Kartasasmita, Cissy B.; Mathew, Joseph L.; Zaman, Syed Mohammad Akram Uz; Paranhos-Baccalà, Gláucia; Bhatnagar, Shinjini; Wadhwa, Nitya; Lodha, Rakesh; Aneja, Satinder; Santosham, Mathuram; Picot, Valentina Sanchez; Sylla, Mariam; Awasthi, Shally; Bavdekar, Ashish; Pape, Jean-William; Rouzier, Vanessa; Chou, Monidarin; Rakoto-Andrianarivelo, Mala; Wang, Jianwei; Nymadawa, Pagbajabyn; Vanhems, Philippe; Russomando, Graciela; Asghar, Rai; Banajeh, Salem; Iqbal, Imran; MacLeod, William; Maulen-Radovan, Irene; Mino, Greta; Saha, Samir; Singhi, Sunit; Thea, Donald M; Clara, Alexey W.; Campbell, Harry; Nair, Harish; Falconer, Jennifer; Williams, Linda J.; Horne, Margaret; Strand, Tor Arne; Qazi, Shamim A.; Nisar, Yasir B.; Neuman, Mark I. (Journal article; Peer reviewed, 2021)Background: Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was to externally validate three such risk scores. Methods: We applied the ... -
Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study
Wang, Xin; Li , You; Deloria-Knoll, Maria; Madhi, Shabir A.; Cohen, Cheryl; Ali, Asad; Basnet, Sudha; Bassat, Quique; Brooks, W Abdullah; Chittaganpitch, Malinee; Echavarria, Marcela; Fasce, Rodrigo A.; Goswami, Doli; Hirve, Siddhivinayak; Homaira, Nusrat; Howie, Stephen R.C.; Kotloff, Karen L.; Khuri-Bulos, Najwa; Krishnan, Anand; Lucero, Marilla G.; Lupisan, Socorro P.; Mira-Iglesias, Ainara; Moore, David P; Moraleda, Cinta; Nunes, Marta; Oshitani, Histoshi; Owor, Betty E.; Polack, Fernando P; O'Brien, Katherine L.; Rasmussen, Zeba A.; Rath, Barbara A; Salimi, Vahid; Scott, J Anthony G; Simões, Eric A F; Strand, Tor A; Thea, Donald M; Treurnicht, Florette K; Vaccari, Linda C; Yoshida, Lay-Myint; Zar, Heather J.; Campbell, Harry; Nair, Harish (Journal article; Peer reviewed, 2020)Background Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human metapneumovirus in children, ... -
Global burden of acute lower respiratory infection associated with human parainfluenza virus in children younger than 5 years for 2018: a systematic review and meta-analysis
Wang, Xin; Li, You; Deloria-Knoll, Maria; Madhi, Shabir A.; Cohen, Cheryl; Arguelles, Vina Lea; Basnet, Sudha; Bassat, Quique; Brooks, W Abdullah; Echavarria, Marcela; Fasce, Rodrigo A.; Gentile, Angela; Goswami, Doli; Homaira, Nusrat; Howie, Stephen R.C.; Kotloff, Karen L.; Khuri-Bulos, Najwa; Krishnan, Anand; Lucero, Marilla G.; Lupisan, Socorro P.; Mathisen, Maria; McLean, Kenneth A; Mira-Iglesias, Ainara; Moraleda, Cinta; Okamoto, Michiko; Oshitani, Histoshi; O'Brien, Katherine L.; Owor, Betty E.; Rasmussen, Zeba; Rath, Barbara A.; Salimi, Vahid; Sawatwong, Pongpun; Scott, J. Anthony; Simões, Eric A F; Sotomayor, Viviana; Thea, Donald M; Treurnicht, Florette K; Yoshida, Lay-Myint; Zar, Heather J.; Campbell, Harry; Nair, Harish (Journal article; Peer reviewed, 2021)Background Human parainfluenza virus (hPIV) is a common virus in childhood acute lower respiratory infections (ALRI). However, no estimates have been made to quantify the global burden of hPIV in childhood ALRI. We aimed ... -
Identifying the research, advocacy, policy and implementation needs for the prevention and management of respiratory syncytial virus lower respiratory tract infection in low- and middle-income countries
Carbonell-Estrany, Xavier; Simões, Eric A. F; Bont, Louis J; Gentile, Angela; Homaira, Nusrat; Scotta, Marcelo Comerlato; Stein, Renato T; Torres, Juan P; Sheikh, Jarju; Broor, Shobha; Khuri-Bulos, Najwa; Nokes, D James; Munywoki, Patrick K; Bassat, Quique; Sharma, Arun K; Basnet, Sudha; Garba, Maria; De Jesus-Cornejo, Joanne; Lupisan, Socorro P; Nunes, Marta C; Divarathna, Maduja; Fullarton, John R; Rodgers-Gray, Barry S; Keary, Ian; Reñosa, Mark Donald C; Verwey, Charl; Moore, David P; Noordeen, Faseeha; Kabra, Sushil; do Vale, Marynéa Silva; Paternina-De La Ossa, Rolando; Mariño, Cristina; Figueras-Aloy, Josep; Krilov, Leonard; Berezin, Eitan; Zar, Heather J; Paudel, Krishna; Safadi, Marco Aurelio Palazzi; Dbaibo, Ghassan; Jroundi, Imane; Jha, Runa; Rafeek, Rukshan A. M; Pinheiro, Rossiclei de Souza; Bracht, Marianne; Muthugala, Rohitha; Lanari, Marcello; Martinón-Torres, Federico; Mitchell, Ian; Irimu, Grace; Pandey, Apsara; Krishnan, Anand; Mejias, Asuncion; da Costa, Marcela Santos Corrêa; Shrestha, Shrijana; Pernica, Jeffrey M; de Carvalho, Felipe Cotrim; Jalango, Rose E; Ibrahim, Hafsat; Ewa, Atana; Ensinck, Gabriela; Ulloa-Gutierrez, Rolando; Miralha, Alexandre Lopes; Lucion, Maria Florencia; Hassan, Md Zakiul; Akhtar, Zubair; Aleem, Mohammad Abdul; Chowdhury, Fahmida; Rojo, Pablo; Sande, Charles; Musau, Abednego; Zaman, Khalequ; Helena, Luiza; Arlant, Falleiros; Ghimire, Prakash; Price, April; Subedi, Kalpana Upadhyay; Brenes-Chacon, Helena; Goswami, Doli Rani; Rahman, Mohammed Ziaur; Hossain, Mohammad Enayet; Chisti, Mohammod Jobayer; Vain, Nestor E; Lim, Audrey; Chiu, Aaron; Papenburg, Jesse; Juarez, Maria del Valle; Senaratne, Thamarasi; Arunasalam, Shiyamalee; Strand, Tor Arne; Ayuk, Adaeze; Ogunrinde, Olufemi; Tavares, Lohanna Valeska de Sousa; Garba, Comfort; Garba, Bilkisu I; Dawa, Jeanette; Gordon, Michelle; Osoro, Eric; Agoti, Charles N; Nyawanda, Bryan; Ngama, Mwanajuma; Tabu, Collins; Mathew, Joseph L; Cornacchia, Andrew; Rai, Ganesh Kumar; Jain, Amita; Giongo, Mateus Sfoggia; Paes, Bosco A (Journal article; Peer reviewed, 2022)Introduction: The high burden of respiratory syncytial virus (RSV) infection in young children disproportionately occurs in low- and middle-income countries (LMICs). The PROUD (Preventing RespiratOry syncytial virUs in ... -
In-hospital mortality risk stratification in children aged under 5 years with pneumonia with or without pulse oximetry: A secondary analysis of the Pneumonia REsearch Partnership to Assess WHO REcommendations (PREPARE) dataset
Hooli, Shubhada; King, Carina; McCollum, Eric D.; Colbourn, Tim; Lufesi, Norman; Mwansambo, Charles; Gregory, Christopher J.; Thamthitiwat, Somsak; Cutland, Clare; Madhi, Shabir Ahmed; Nunes, Marta C.; Gessner, Bradford D.; Hazir, Tabish; Mathew, Joseph L.; Addo-Yobo, Emmanuel; Chisaka, Noel; Hassan, Mumtaz; Hibberd, Patricia L.; Jeena, Prakash; Lozano, Juan M.; MacLeod, William B.; Patel, Archana; Thea, Donald M.; Nguyen, Ngoc Tuong Vy; Zaman, Syed MA.; Ruvinsky, Raul O.; Lucero, Marilla; Kartasasmita, Cissy B.; Turner, Claudia; Asghar, Rai; Banajeh, Salem; Iqbal, Imran; Maulen-Radovan, Irene; Mino-Leon, Greta; Saha, Samir K.; Santosham, Mathuram; Singhi, Sunit; Awasthi, Shally; Bavdekar, Ashish; Chou, Monidarin; Nymadawa, Pagbajabyn; Pape, Jean-William; Paranhos-Baccala, Glaucia; Picot, Valentina Sanchez; Rakoto-Andrianarivelo, Mala; Rouzier, Vanessa; Russomando, Graciela; Sylla, Mariam; Vanhems, Philippe; Wang, Jianwei; Basnet, Sudha; Strand, Tor Arne; Neuman, Mark I.; Arroyo, Luis Martinez; Echavarria, Marcela; Bhatnagar, Shinjini; Wadhwa, Nitya; Lodha, Rakesh; Aneja, Satinder; Gentile, Angela; Chadha, Mandeep; Hirve, Siddhivinayak; O'Grady, Kerry-Ann F.; Clara, Alexey W.; Rees, Chris A.; Campbell, Harry; Nair, Harish; Falconer, Jennifer; Williams, Linda J.; Horne, Margaret; Qazi, Shamim A.; Nisar, Yasir Bin (Journal article; Peer reviewed, 2023)Objectives: We determined the pulse oximetry benefit in pediatric pneumonia mortality risk stratification and chest-indrawing pneumonia in-hospital mortality risk factors. Methods: We report the characteristics and ... -
Predictors of Duration and Treatment Failure of Severe Pneumonia in Hospitalized Young Nepalese Children
Basnet, Sudha; Sharma, Arun; Mathisen, Maria; Shrestha, Prakash Sunder; Ghimire, Ram Kumar; Shrestha, Dhiraj Man; Valentiner-Branth, Palle; Sommerfelt, Halvor; Strand, Tor A. (Peer reviewed; Journal article, 2015-03-23)Background. Pneumonia in young children is still the most frequent cause of death in developing countries. We aimed to identify predictors for recovery and treatment failure in children hospitalized with severe pneumonia. ... -
RNA viruses in community-acquired childhood pneumonia in semi-urban Nepal; a cross-sectional study
Mathisen, Maria; Strand, Tor A.; Sharma, Biswa N.; Chandyo, Ram Krishna; Valentiner-Branth, Palle; Basnet, Sudha; Adhikari, Ramesh K.; Hvidsten, Dag; Shrestha, Prakash S.; Sommerfelt, Halvor (Peer reviewed; Journal article, 2009-07-27)Background: Pneumonia is among the main causes of illness and death in children <5 years of age. There is a need to better describe the epidemiology of viral community-acquired pneumonia (CAP) in developing countries. ... -
Severe pneumonia in hospitalized young Nepalese children. Studies on the efficacy of oral zinc, respiratory viruses and prognostic determinants
Basnet, Sudha (Doctoral thesis, 2016-04-19)Pneumonia is a leading cause of death in children less than five years of age in low and middle income countries and contributes importantly to their disease burden. Zinc, essential for normal function of the immune system, ...