Browsing Faculty of Medicine by Subject "Homocysteine"

Now showing items 1-4 of 4

    • Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-Vitamin supplementation 

      Holm, Pål Ivar; Bleie, Øyvind; Ueland, Per Magne; Lien, Ernst Asbjørn; Refsum, Helga; Nordrehaug, Jan Erik; Nygård, Ottar (Peer reviewed; Journal article, 2004)
      Objective—Betaine is a substrate in the betaine– homocysteine methyltransferase reaction, converting homocysteine to methionine. There are only sparse data on plasma betaine as a determinant of the plasma total homocysteine ...

    • Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency 

      Hannibal, Luciana; Lysne, Vegard; Bjørke-Monsen, Anne-Lise; Behringer, Sidney; Grünert, Sarah C.; Spiekerkoetter, Ute; Jacobsen, Donald W.; Blom, Henk J. (Peer reviewed; Journal article, 2016-06-27)
      Vitamin B12 (cobalamin, Cbl, B12) is an indispensable water-soluble micronutrient that serves as a coenzyme for cytosolic methionine synthase (MS) and mitochondrial methylmalonyl-CoA mutase (MCM). Deficiency of Cbl, whether ...

    • Dietary predictors of plasma total homocysteine concentration in the Hordaland Homocysteine Study 

      Konstantinova, Svetlana V.; Vollset, Stein Emil; Berstad, Paula; Ueland, Per Magne; Drevon, Christian A.; Refsum, Helga; Tell, Grethe Seppola (Peer reviewed; Journal article, 2007)
      Established dietary predictors of plasma total homocysteine (tHcy) include folate, riboflavin, and vitamins B6 and B12, while information is scarce regarding other dietary components. The aim of this study was to examine ...

    • The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A 

      Olsen, Thomas; Vinknes, Kathrine; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Dhar, Indu; Tell, Grethe S.; Blomhoff, Rune; Ueland, Per Magne; Midttun, Øivind; Refsum, Helga; Nygård, Ottar (Peer reviewed; Journal article, 2018)
      Background. Plasma total homocysteine (tHcy) has been implicated in the development of cardiovascular disease, but the mechanisms remain unclear. Vitamin A (Vit-A) is involved in homocysteine metabolism and we therefore ...