Blar i Faculty of Medicine på emneord "LAIV"

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    • Boosting of cross-reactive and protection-associated T cells in children after live attenuated influenza vaccination 

      Mohn, Kristin Greve-Isdahl; Zhou, Fan; Brokstad, Karl Albert; Sridhar, Saranya; Cox, Rebecca Jane (Peer reviewed; Journal article, 2017-05)
      Background. Live attenuated influenza vaccines (LAIVs) stimulate a multifaceted immune response including cellular immunity, which may provide protection against newly emerging strains. This study shows proof of concept ...

    • Live attenuated influenza vaccine in children induces b-cell responses in tonsils 

      Mohn, Kristin Greve-Isdahl; Brokstad, Karl Albert; Pathirana, Rishi; Bredholt, Geir; Jul-Larsen, Åsne; Trieu, Mai Chi; Jalloh, Sarah Larteley Lartey; Montemoli, Emanuele; Tøndel, Camilla; Aarstad, Hans Jørgen; Cox, Rebecca Jane (Peer reviewed; Journal article, 2016)
      Background. Tonsils play a key role in eliciting immune responses against respiratory pathogens. Little is known about how tonsils contribute to the local immune response after intranasal vaccination. Here, we uniquely ...

    • Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children 

      Mohn, Kristin Greve-Isdahl; Bredholt, Geir; Brokstad, Karl Albert; Pathirana, Rishi; Aarstad, Hans Jørgen; Tøndel, Camilla; Cox, Rebecca Jane (Peer reviewed; Journal article, 2015-05-15)
      Background. The live attenuated influenza vaccine (LAIV) is the preferred vaccine for children, but the mechanisms behind protective immune responses are unclear, and the duration of immunity remains to be elucidated. This ...