Now showing items 75-87 of 87

  • Salivary glands of primary Sjögren’s syndrome patients express factors vital for plasma cell survival 

    Szyszko, Ewa A.; Brokstad, Karl Albert; Øijordsbakken, Gunnvor; Jonsson, Malin Viktoria; Jonsson, Roland; Skarstein, Kathrine (BioMed Central, 2011-01-07)
    Introduction: The presence of circulating Ro/SSA and La/SSB autoantibodies has become an important marker in the classification criteria for primary Sjögren’s syndrome (pSS). Plasma cells producing these autoantibodies ...
    Peer reviewedJournal article
  • Secreted proteins and surface markers on tubercle bacilli 

    Målen, Hiwa (The University of Bergen, 2007-12-12)
    Tuberculosis caused by Mycobacterium tuberculosis (M. tuberculosis) is the major cause of mortality and morbidity of over two million people each year. Mapping of proteins exported by the pathogen to the extracellular ...
    Doctoral thesis
  • Secreted proteins of mycobacteria and their role during infection 

    Leversen, Nils Anders (The University of Bergen, 2012-03-23)
    One-third of the world’s population is infected with the causative agent of tuberculosis, Mycobacterium tuberculosis. A fraction of infected individuals have an active form of the disease, while the remainder is able to ...
    Doctoral thesis
  • Serodiagnosis of tuberculous lymphadenitis using a combination of antigens 

    Beyene, Demissew Balcha; Franken, Kees Lumc; Yamuah, Lawrence; Aseffa, Abraham; Wiker, Harald G.; Kolk, Arend; Engers, Howard; Klatser, Paul R.; Sviland, Lisbet (Open Learning on Enteric Pathogens, 2010)
    Background: The diagnosis of extra-pulmonary tuberculosis (EPTB) by conventional methods such as culture and microscopy has low sensitivity and requires an invasive procedure. A simple rapid serological test would be of ...
    Journal articlePeer reviewed
  • Sjögren’s syndrome: studying the disease in mice 

    Delaleu, Nicolas Hervé; Nguyen, Cuong Q.; Peck, Ammon B.; Jonsson, Roland (BioMed Central, 2011-06-13)
    Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function. Clinical symptoms develop late and there are ...
    Peer reviewedJournal article
  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies 

    Schmidt, Marjanka K.; Leeuwen, Flora E. van; Wesseling, Jelle; Cheang, Maggie C. U.; Gelmon, Karen; Nielsen, Torsten O.; Blomqvist, Carl; Heikkilä, Päivi; Heikkinen, Tuomas; Broeks, Annegien; Nevanlinna, Heli; Akslen, Lars A.; Bégin, Louis R.; Foulkes, William D.; Couch, Fergus J.; Wang, Xianshu; Cafourek, Vicky; Olson, Janet E.; Baglietto, Laura; Giles, Graham G.; Severi, Gianluca; McLean, Catriona A.; Southey, Melissa C.; Rakha, Emad; Green, Andrew R.; Ellis, Ian O.; Sherman, Mark E.; Lissowska, Jolanta; Anderson, William F.; Cox, Angela; Cross, Simon S.; Reed, Malcolm W. R.; Provenzano, Elena; Dawson, Sarah-Jane; Dunning, Alison M.; Humphreys, Manjeet; Easton, Douglas F.; García-Closas, Montserrat; Caldas, Carlos; Pharoah, Paul D.; Huntsman, David G.; Blows, Fiona M.; Driver, Kristy E. (Public Library of Science, 2010-05-25)
    Background Immunohistochemical markers are often used to classify breast cancer into subtypes that are biologically distinct and behave differently. The aim of this study was to estimate mortality for patients with the ...
    Peer reviewedJournal article
  • Time-dependent clock gene expression in mouse and human stem and progenitor cells 

    Tsinkalovsky, Oleg (The University of Bergen, 2007-03-30)
    Time is a fundamental part of all biological processes. During the whole process of evolution, living cells and organisms had to adapt to cyclic variations in the environment. In particular, the light and temperature ...
    Doctoral thesis
  • Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach 

    Paraskevis, Dimitrios; Pybus, Oliver; Magiorkinis, Gkikas; Hatzakis, Angelos; Wensing, Annemarie M. J.; van de Vijver, David A.; Albert, Jan; Angarano, Guiseppe; Åsjø, Birgitta; Balotta, Claudia; Boeri, Enzo; Camacho, Ricardo; Chaix, Marie-Laure; Coughlan, Suzie; Costagliola, Dominique; De Luca, Andrea; de Mendoza, Carmen; Derdelinckx, Inge; Grossman, Zehava; Hamouda, Osama; Hoepelman, I. M.; Horban, Andrzej; Korn, Klaus; Kücherer, Claudia; Leitner, Thomas; Loveday, Clive; MacRae, Eilidh; Maljkovic-Berry, I.; Meyer, Laurence; Nielsen, Claus; Op de Coul, Eline L. M.; Ormaasen, Vidar; Perrin, Luc; Puchhammer-Stöckl, Elisabeth; Ruiz, Lidia; Salminen, Mika O.; Schmit, Jean-Claude; Schuurman, Rob; Soriano, Vincent; Stanczak, J.; Stanojevic, Maja; Struck, Daniel; Van Laethem, Kristel; Violin, M.; Yerly, Sabine; Zazzi, Maurizio; Boucher, Charles A.; Vandamme, Anne-Mieke; the SPREAD Programme (BioMed Central, 2009-05-20)
    Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic from ...
    Journal article
  • Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients 

    Theys, Kristof; Deforche, Koen; Vercauteren, Jurgen; Libin, Pieter; van de Vijver, David A. M. C.; Albert, Jan; Åsjø, Birgitta; Balotta, Claudia; Bruckova, Marie; Camacho, Ricardo J.; Clotet, Bonaventura; Coughlan, Suzie; Grossman, Zehava; Hamouda, Osamah; Horban, Andrzei; Korn, Klaus; Kostrikis, Leondios G.; Kücherer, Claudia; Nielsen, Claus; Paraskevis, Dimitrios; Poljak, Mario; Puchhammer-Stockl, Elisabeth; Riva, Chiara; Ruiz, Lidia; Liitsola, Kirsi; Schmit, Jean-Claude; Schuurman, Rob; Sönnerborg, Anders; Stanekova, Danica; Stanojevic, Maja; Struck, Daniel; Van Laethem, Kristel; Wensing, Annemarie M. J.; Boucher, Charles A. B.; Vandamme, Anne-Mieke; on behalf of the SPREAD-programme (BioMed Central, 2012-10-03)
    Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
    Journal article
  • Tumor necrosis is associated with increased alphav beta3 integrin expression and poor prognosis in nodular cutaneous melanomas 

    Bachmann, Ingeborg M.; Ladstein, Rita Grude; Straume, Oddbjørn; Naumov, George N.; Akslen, Lars A. (BioMed Central, 2008-12-05)
    Background: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas of ...
    Journal article
  • Type 1 plasminogen activator inhibitor (PAI-1) in clear cell renal cell carcinoma (CCRCC) and its impact on angiogenesis, progression and patient survival after radical nephrectomy 

    Zubac, Dragomir; Wentzel-Larsen, Tore; Seidal, Tomas; Bostad, Leif (BioMed Central, 2010-12-03)
    Background To examine the expression of type 1 plasminogen inhibitor (PAI-1) in clear cell renal cell carcinoma (CCRCC), and its possible association with microvessel density (MVD), the expression of thrombospondin-1 ...
    Journal articlePeer reviewed
  • Use of immunohistochemical markers can refine prognosis in triple negative breast cancer 

    Tischkowitz, Marc; Brunet, Jean-Sébastien; Bégin, Louis R.; Huntsman, David G.; Cheang, Maggie C. U.; Akslen, Lars A.; Nielsen, Torsten O.; Foulkes, William D. (BioMed Central, 2007-07-24)
    Background: Basal-like breast cancer has been extensively characterized on the basis of gene expression profiles, but it is becoming increasingly common for these tumors to be defined on the basis of immunohistochemical ...
    Journal articlePeer reviewed
  • Uterine cervical neoplasia : aspects of biology and pathology 

    Bertelsen, Bjørn I. (The University of Bergen, 2007-01-18)
    Doctoral thesis