Now showing items 21-30 of 90
Comprehensive Analysis of Exported Proteins from Mycobacterium tuberculosis H37Rv
(Wiley-VCH Verlag Berlin, 2007-04-21)
Proteins secreted by Mycobacterium tuberculosis play an essential role in the pathogenesis of tuberculosis. The culture filtrates of M. tuberculosis H37Rv made by Sadamu Nagai (Japan), are considerably enriched for secreted ...
Evidence for waning of latency in a cohort study of tuberculosis
(BioMed Central, 2010-02-23)
Background To investigate how the risk of active tuberculosis disease is influenced by time since original infection and to determine whether the risk of reactivation of tuberculosis increases or decreases with ...
Gastric adenocarcinoma: aspects of development and progression in high- and low-risk countries
(The University of Bergen, 2010-03-25)
CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without hiv co-infection
(BioMed Central, 2012-03-21)
<p>Background: The interaction of HIV and tuberculosis (TB) on CD4 levels over time is complex and has been divergently reported.</p> <p>Methods: CD4 counts were assessed from time of diagnosis till the end of TB treatment ...
Expression Profiling of Major Histocompatibility and Natural Killer Complex Genes Reveals Candidates for Controlling Risk of Graft versus Host Disease
(Public Library of Science, 2011-01-28)
Background: The major histocompatibility complex (MHC) is the most important genomic region that contributes to the risk of graft versus host disease (GVHD) after haematopoietic stem cell transplantation. Matching of MHC ...
Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies
(BioMed Central, 2011-06-28)
<p>Background: Cervical intraepithelial neoplasia (CIN) grades 2 and 3 are usually grouped and treated in the same way as “high grade”, in spite of their different risk to cancer progression and spontaneous regression ...
Tumor necrosis is associated with increased alphav beta3 integrin expression and poor prognosis in nodular cutaneous melanomas
(BioMed Central, 2008-12-05)
<p>Background: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas ...
Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains
(BioMed Central, 2011-01-24)
Background: The potential causes for variation in virulence between distinct M. tuberculosis strains are still not fully known. However, differences in protein expression are probably an important factor. In this study ...
Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
(American Society for Biochemistry and Molecular Biology, 2011-01)
Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
(BioMed Central, 2011-01-05)
Background: Design of tumour specific immunotherapies using the patients’ own dendritic cells (DC) is a fast advancing scientific field. The functional qualities of the DC generated in vitro are critical, and today’s ...