Now showing items 31-40 of 90
Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations
(BioMed Central, 2008-02-20)
Introduction Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly targets the exocrine glands. The aim of this study was to investigate the involvement of 87 proteins measured in serum and 75 proteins ...
Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
(BioMed Central, 2012-10-03)
<p>Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach
(BioMed Central, 2009-05-20)
<p>Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic ...
Expression of ESE-3 Isoforms in Immunogenic and Tolerogenic Human Monocyte-Derived Dendritic Cells
(Public Library of Science, 2012-11-19)
Dendritic cells (DC) are the only hematopoietic cells expressing the epithelial specific Ets transcription factor ESE-3. Here we analyzed presence and quantity of isoforms ESE-3a, ESE-3b and ESE-3j in various immunogenic ...
Effect of Ascaris Lumbricoides specific IgE ontuberculin skin test responses in children in a high-burdensetting: a cross-sectional community-based study
(BioMed Central, 2012-09-11)
<p>Background: M.tuberculosis (M.tb) is associated with enhanced T helper cell type 1 (Th1) immune responses while helminth infection is associated with T helper cell type 2 (Th2) immune responses. Our aim was to investigate ...
Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma
(BioMed Central, 2010-04-14)
Background: Tumor cell proliferation is a predictor of survival in cutaneous melanoma. The aim of the present study was to evaluate the prognostic impact of mitotic count, Ki-67 expression and novel proliferation markers ...
Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas
(BioMed Central, 2008-02-08)
Background It has been suggested that a small population of cells with unique self-renewal properties and malignant potential exists in solid tumors. Such "cancer stem cells" have been isolated by flow cytometry, followed ...
The autonomy of different aspects of Sjögren´s syndrome and their treatment in an experimental model: the use of comprehensive biomarker analyses to characterize the disease and the effect of heat-shock proteins in treatment intervention
(The University of Bergen, 2008-06-20)
Sjögren’s syndrome (SS) is a systemic rheumatic disease, in which the salivary and lacrimal glands are the principal targets of a pathological autoimmune reaction. Clinically, SS is manifested by keratoconjunctivitis ...
ERG and SIM2 transcription factors in prostate cancer – their role in carcinogenesis and potential clinical utility
(The University of Bergen, 2011-01-27)
Burkitt Lymphoma in Uganda. A study of some biological and epidemiological aspects of endemic Burkitt lymphoma
(The University of Bergen, 2011-08-25)