Now showing items 61-70 of 90
Gene signatures and prognostic factors in endometrial cancer. A study with special focus on vascular invasion
(The University of Bergen, 2011-04-15)
Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort : a case control study
(BioMed Central, 2006-03-16)
<p>Background: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of developing cancer. For colorectal cancer the importance of mutations ...
Time-dependent clock gene expression in mouse and human stem and progenitor cells
(The University of Bergen, 2007-03-30)
Time is a fundamental part of all biological processes. During the whole process of evolution, living cells and organisms had to adapt to cyclic variations in the environment. In particular, the light and temperature ...
pRb2/p130 protein expression and RBL2 mutation analysis in Burkitt lymphoma from Uganda
(BioMed Central, 2009-08-19)
Background: The members of the retinoblastoma protein family, pRb, p107 and pRb2 (p130), are central players in controlling the cell cycle. Whereas disturbed function of pRb is commonly seen in human cancers, it is still ...
Clinical Efficacy and Safety of Bevacizumab Monotherapy in Patients with Metastatic Melanoma: Predictive Importance of Induced Early Hypertension
(Public Library of Science, 2012-06-15)
<p>Background: VEGF driven angiogenesis plays a key role in cancer progression. We determined the clinical efficacy of bevacizumab monotherapy in patients with metastatic melanoma.</p> <p>Methods and Findings: Thirty-five ...
Birth length and weight as predictors of breast cancer prognosis
(BioMed Central, 2010-03-26)
Background Birth size, and particularly birth length, is positively associated with breast cancer risk in adulthood. The objective of this study was to examine whether birth size is associated with survival among breast ...
Sjögren’s syndrome: studying the disease in mice
(BioMed Central, 2011-06-13)
Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function. Clinical symptoms develop late and there are ...
The HELLP syndrome: clinical issues and management. A Review
(The University of Bergen, 2009-02-26)
<p>Background: The HELLP syndrome is a serious complication in pregnancy characterized by haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all pregnancies and in 10–20% of cases ...
Biological Characteristics of Stem-Like Cells in Oral Squamous Cell Carcinoma
(The University of Bergen, 2013-06-18)
<p>It has been shown that many solid malignancies, including oral squamous cell carcinoma (OSCC), contain a small population of tumorigenic cells referred to as cancer stem-like cells (CSCs) or tumor initiating cells ...
The link between periodontal disease and rheumatoid arthritis: An updated review
Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process involving progressive destruction of the tissues that support the teeth. Recently, the organism has been reported to produce a ...