Now showing items 1-10 of 20
Age specific aetiological agents of diarrhoea in hospitalized children aged less than five years in Dar es Salaam, Tanzania
(BioMed Central, 2011-02-23)
Background This study aimed to determine the age-specific aetiologic agents of diarrhoea in children aged less than five years. The study also assessed the efficacy of the empiric treatment of childhood diarrhoea using ...
Detection and molecular characterization of herpes simplex virus from Tanzania and Norway
(The University of Bergen, 2006-12-22)
Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
(BioMed Central, 2012-10-03)
<p>Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
Secreted proteins and surface markers on tubercle bacilli
(The University of Bergen, 2007-12-12)
Tuberculosis caused by Mycobacterium tuberculosis (M. tuberculosis) is the major cause of mortality and morbidity of over two million people each year. Mapping of proteins exported by the pathogen to the extracellular ...
High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example
(BioMed Central, 2008-07-02)
<p>Background: While the genomic annotations of diverse lineages of the Mycobacterium tuberculosis complex are available, divergences between gene prediction methods are still a challenge for unbiased protein dataset ...
Functional analysis of tilS homologues in Bacteria and Archaea
(The University of Bergen, 2005-09-09)
Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ...
Ectopic germinal center formation in Sjögren’s syndrome: Significance of lymphoid organization
(The University of Bergen, 2006-06-23)
Sjögren’s syndrom (SS) is an autoimmune, chronic inflammatory disorder predominantly affecting the salivary and lacrimal glands. The overall aim of this study was to determine clinicopathological features in human and ...
Serodiagnosis of tuberculous lymphadenitis using a combination of antigens
(Open Learning on Enteric Pathogens, 2010)
<p>Background: The diagnosis of extra-pulmonary tuberculosis (EPTB) by conventional methods such as culture and microscopy has low sensitivity and requires an invasive procedure. A simple rapid serological test would be ...
Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
(American Society for Biochemistry and Molecular Biology, 2011-01)
Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...
CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without hiv co-infection
(BioMed Central, 2012-03-21)
<p>Background: The interaction of HIV and tuberculosis (TB) on CD4 levels over time is complex and has been divergently reported.</p> <p>Methods: CD4 counts were assessed from time of diagnosis till the end of TB treatment ...