Now showing items 61-70 of 193
Differential expression patterns of conserved miRNAs and isomiRs during Atlantic halibut development
(BioMed Central, 2012-01-10)
<p>Background: MicroRNAs (miRNAs) play a major role in animal ontogenesis. Size variants of miRNAs, isomiRs, are observed along with the main miRNA types, but their origin and possible biological role are uncovered ...
Normalized gradient fields for nonlinear motion correction of DCE-MRI time series
(ElsevierComputerized Medical Imaging Society, 2014-04)
Dynamic MR image recordings (DCE-MRI) of moving organs using bolus injections create two differenttypes of dynamics in the images: (i) spatial motion artifacts due to patient movements, breathing andphysiological pulsations ...
Natural killer cells in intracranial neoplasms: presence and therapeutic efficacy against brain tumours
Natural killer (NK) cells are lymphocytes that play an important role in anti-tumour immunity. Their potential against brain cancer has been demonstrated in vitro and in vivo, both as a direct anti-tumour agent and in ...
Studies of α11β1 integrin in the mouse and human periodontal ligament
(The University of Bergen, 2009-06-12)
Correlations between measures of executive attention and cortical thickness of left posterior middle frontal gyrus - a dichotic listening study
(BioMed Central, 2009-10-01)
<p>Background: The frontal lobe has been associated to a wide range of cognitive control functions and is also vulnerable to degeneration in old age. A recent study by Thomsen and colleagues showed a difference between ...
Altered DNA methylation profile in Norwegian patients with Autoimmune Addison’s Disease
Autoimmune Addison's Disease (AAD) is an endocrine and immunological disease of uncertain pathogenesis resulting from the immune system's destruction of the hormone producing cells of the adrenal cortex. The underlying ...
Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer
(Public Library of Science, 2011-01-31)
Duplication of chromosomal arm 20q occurs in prostate, cervical, colon, gastric, bladder, melanoma, pancreas and breast cancer, suggesting that 20q amplification may play a causal role in tumorigenesis. According to an ...
Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK
(Cell Press, 2014-11-20)
BDNF signaling contributes to protein-synthesis-dependent synaptic plasticity, but the dynamics of TrkB signaling and mechanisms of translation have not been defined. Here, we show that long-term potentiation (LTP) ...
Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
(American Society for Biochemistry and Molecular Biology, 2011-01)
Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...