Browsing Department of Biomedicine by Subject "Brain tumour"

Now showing items 1-2 of 2

    • Dactolisib (NVP-BEZ235) toxicity in murine brain tumour models 

      Netland, I. A; Førde, H. E; Sleire, L.; Leiss, L.; Rahman, M. A; Skeie, B. S; Gjerde, C. H; Enger, P. Ø; Goplen, D. (Peer reviewed; Journal article, 2016-08-19)
      Background: Glioblastomas (GBMs) are highly malignant brain tumours with a poor prognosis, and current cytotoxic regimens provide only a limited survival benefit. The PI3K/Akt/mTOR pathway has been an attractive target for ...

    • Natural killer cells in intracranial neoplasms: presence and therapeutic efficacy against brain tumours 

      Kmiecik, Justyna; Zimmer, Jacques; Chekenya, Martha (Peer reviewed; Journal article, 2014-01)
      Natural killer (NK) cells are lymphocytes that play an important role in anti-tumour immunity. Their potential against brain cancer has been demonstrated in vitro and in vivo, both as a direct anti-tumour agent and in ...