Blar i Department of Biomedicine på forfatter "Hammarsten, Ola"
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Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets
Micklem, David Robert; Blø, Magnus; Bergström, Petra; Hodneland, Erlend; Tiron, Crina Elena; Høiby, Torill; Gjerdrum, Christine; Hammarsten, Ola; Lorens, James B. (Peer reviewed; Journal article, 2014-06-21)Background: The dose-response relationship is a fundamental pharmacological parameter necessary to determine therapeutic thresholds. Epi-allelic hypomorphic analysis using RNA interference (RNAi) can similarly correlate ... -
Novel clearance of muscle proteins by muscle cells
Muslimovic, Aida; Friden, Vincent; Starnberg, Karin; Tenstad, Olav; Espedal, Heidi; Vukusic, Kristina; Nyström, Susanne; Wesén, Emelie; Esbjörner, Elin K; Granholm, Kristoffer; Lindahl, Bertil; Hammarsten, Ola (Journal article; Peer reviewed, 2020)Blood levels of cardiac troponins (cTn) and myoglobin are analysed when myocardial infarction (MI) is suspected. Here we describe a novel clearance mechanism for muscle proteins by muscle cells. The complete plasma clearance ...