Blar i Department of Biomedicine på forfatter "Hodneland, Erlend"
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Biomedical Image Processing in the Study of Living Cells
Hodneland, Erlend (Doctoral thesis, 2008-12-09) -
CellSegm - a MATLAB toolbox for high-throughput 3D cell segmentation
Hodneland, Erlend; Kögel, Tanja; Frei, Dominik M.; Gerdes, Hans-Hermann; Lundervold, Arvid (Peer reviewed; Journal article, 2013-08-09)The application of fluorescence microscopy in cell biology often generates a huge amount of imaging data. Automated whole cell segmentation of such data enables the detection and analysis of individual cells, where a manual ... -
Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets
Micklem, David Robert; Blø, Magnus; Bergström, Petra; Hodneland, Erlend; Tiron, Crina Elena; Høiby, Torill; Gjerdrum, Christine; Hammarsten, Ola; Lorens, James B. (Peer reviewed; Journal article, 2014-06-21)Background: The dose-response relationship is a fundamental pharmacological parameter necessary to determine therapeutic thresholds. Epi-allelic hypomorphic analysis using RNA interference (RNAi) can similarly correlate ... -
Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles - A longitudinal MRI study of 76 middle-aged and older adults
Vik, Alexandra; Hodneland, Erlend; Haász, Judit; Ystad, Martin Andreas; Lundervold, Astri; Lundervold, Arvid (Peer reviewed; Journal article, 2015-05-15)Motivated by the frontal- and white matter (WM) retrogenesis hypotheses and the assumptions that fronto-striatal circuits are especially vulnerable in normal aging, the goal of the present study was to identify fiber bundles ... -
Normalized gradient fields for nonlinear motion correction of DCE-MRI time series
Hodneland, Erlend; Lundervold, Arvid; Rørvik, Jarle; Munthe-Kaas, Antonella Zanna (Peer reviewed; Journal article, 2014-04)Dynamic MR image recordings (DCE-MRI) of moving organs using bolus injections create two differenttypes of dynamics in the images: (i) spatial motion artifacts due to patient movements, breathing andphysiological pulsations ... -
Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer
Frei, Dominik Michael; Hodneland, Erlend; Rios-Mondragon, Ivan; Burtey, Anne Pierrette; Neumann, B; Bulkescher, Jutta; Schölermann, Julia; Pepperkok, Rainer; Gerdes, Hans-Hermann; Kögel, Tanja (Peer reviewed; Journal article, 2015-08-14)Contact-dependent intercellular transfer (codeIT) of cellular constituents can have functional consequences for recipient cells, such as enhanced survival and drug resistance. Pathogenic viruses, prions and bacteria can ... -
Segmentation-Driven Image Registration-Application to 4D DCE-MRI Recordings of the Moving Kidneys
Hodneland, Erlend; Hanson, Erik Andreas; Lundervold, Arvid; Modersitzki, Jan; Eikefjord, Eli Bjøvad; Zanna, Antonella (Peer reviewed; Journal article, 2014-04-01)Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of the kidneys requires proper motion correction and segmentation to enable an estimation of glomerular filtration rate through pharmacokinetic modeling. ... -
Semi-automatic 3D morphological reconstruction of neurons with densely branching morphology: Application to retinal AII amacrine cells imaged with multi-photon excitation microscopy
Zandt, Bas-Jan; Losnegård, Are; Hodneland, Erlend; Veruki, Margaret Lin; Lundervold, Arvid; Hartveit, Espen (Peer reviewed; Journal article, 2017-03)Background: Accurate reconstruction of the morphology of single neurons is important for morphometric studies and for developing compartmental models. However, manual morphological reconstruction can be extremely time-consuming ...