Blar i Department of Biomedicine på emneord "Hypoxia"
Viser treff 1-3 av 3
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Impact of hypoxia on the expression of cell line markers and behavior of cultured glioma cell lines
(Master thesis, 2011-06-01)Glioblastoma multiforme (GBM) constitute over 50 % of primary brain tumors in adults. The tumor is heterogeneous and highly infiltrative. Its nature makes it extremely aggressive and incurable. Thus, today's treatment ... -
Regulation of CDKN2B expression by interaction of Arnt with Miz-1 - a basis for functional integration between the HIF and Myc gene regulatory pathways
(Peer reviewed; Journal article, 2014-03-11)Background: Hypoxia- and Myc-dependent transcriptional regulatory pathways are frequently deregulated in cancer cells. These pathways converge in many cellular responses, but the underlying molecular mechanisms are unclear. ... -
Role of Caveolin-1 in Hypoxia and Proneural to Mesenchymal Transition of Glioblastoma
(Master thesis, 2018-06-29)Glioblastomas (GBM), a grade IV astrocytoma, is the most common and aggressive primary brain tumors in adults, associated with short survival and uniformly fatal outcome irrespective of treatment. GBM is highly heterogeneous ...