Now showing items 1-10 of 211
Prevalence and implications of elevated microsatellite alterations at selected tetranucleotides in cancer
(Nature Publishing Group, 2014-04-01)
Elevated microsatellite alterations at selected tetranucleotides (EMAST), a variation of microsatellite instability (MSI), has been reported in a variety of malignancies (e.g., neoplasias of the lung, head and neck, ...
Characterisation of genomic imbalances in patients with mental retardation
(The University of Bergen, 2009-03-20)
A major cause of mental retardation is chromosomal abnormalities, but due to low sensitivity of conventional chromosomal karyotyping, these abnormalities may stay undetected, and the etiology of the impairment remains ...
A randomized phase II pre-surgical trial of weekly low-dose tamoxifen versus raloxifene versus placebo in premenopausal women with estrogen receptor positive breast cancer
(BioMed Central, 2013-06-20)
<p>Introduction: We previously demonstrated that 1 or 5 mg per day of tamoxifen (T) given for four weeks before surgery reduces Ki-67 in breast cancer (BC) patients to the same extent as the standard 20 mg/d. Given the ...
The Low Affinity Nerve Growth Factor Receptor p75NTR Identifies a Transient Stem Cell-Like State in Oral Squamous Cell Carcinoma Cells
<p>Background Although several markers have been used for enrichment of cells with stem cell-like properties in oral squamous cell carcinoma (OSCC), isolation of a pure subpopulation is still a challenging task. Normal ...
Short-term outcome of 1,465 computer-navigated primary total knee replacements 2005–2008. A report from the Norwegian Arthroplasty Register
(Informa Healthcare, 2011-06)
<p>Background and purpose: Improvement of positioning and alignment by the use of computer-assisted surgery (CAS) might improve longevity and function in total knee replacements, but there is little evidence. In this ...
Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment
(Public Library of Science, 2012-11-30)
<p>Background: Psychiatric patients often require chronic treatment with antipsychotic drugs, and while rats are frequently used to study antipsychotic-induced metabolic adverse effects, long-term exposure has only partially ...
HPV DNA testing improves CIN2+ risk stratification and detection of CIN2+ in delayed triage of ASCUS and LSIL. A population-based follow-up study from Western Norway
In Norway, Pap smears with atypical squamous cells of uncertain significance (ASCUS) and low-grade squamous intraepithelial lesions (LSIL) are triaged after 6 months. The aim of the study was to evaluate effects of ...
Myasthenia gravis; cytotoxic potential of human sera in vitro and novel non-antibody, disease-modifying factors
(The University of Bergen, 2010-10-22)
Adult attention deficit hyperactivity disorder is associated with migraine headaches
Attention deficit hyperactivity disorder (ADHD) is now recognized as a common disorder both in child and adult psychiatry. Adult patients with a diagnosis of ADHD (n = 572) and community controls (n = 675) responded ...
General practitioners' opinions on how to improve treatment of mental disorders in primary health care. Interviews with one hundred Norwegian general practitioners
(BioMed Central, 2010-02-09)
Background Improvements in treatment of mental disorders are repeatedly called for. General practitioners (GPs) are responsible for the majority of treatment of mental disorders. Consequently, we interviewed GPs about ...