Now showing items 1-3 of 3
Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer
(BioMed Central, 2010-06-21)
Background The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and ...
Anti-Interferon Autoantibodies in Autoimmune Polyendocrinopathy Syndrome Type 1
(Public Library of Science, 2006-06-13)
Background The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM 240300), recessive AIRE mutations lead to autoimmunity targetting ...
Nuclear Receptor Coregulators Role of Protein-Protein Interactions and cAMP/PKA Signaling
(The University of Bergen, 2007-02-02)