Blar i Faculty of Psychology på forfatter "Hugdahl, Kenneth"
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Assessing brain structural associations with working-memory related brain patterns in schizophrenia and healthy controls using linked independent component analysis
Brandt, Christine Lycke; Doan, Nhat Trung; Tønnesen, Siren; Agartz, Ingrid; Hugdahl, Kenneth; Melle, Ingrid; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2015)Schizophrenia (SZ) is a psychotic disorder with significant cognitive dysfunction. Abnormal brain activation during cognitive processing has been reported, both in task-positive and task-negative networks. Further, structural ... -
The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths
Ousdal, Olga Therese; Milde, Anne Marita; Hafstad, Gertrud Sofie; Hodneland, Erlend; Dyb, Grete; Craven, Alexander R.; Melinder, Annika Maria D; Endestad, Tor; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)The amygdala is a core component in neurobiological models of stress and stress-related pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have reported increased amygdala activity following ... -
Auditory hallucinations, top-down processing and language perception: a general population study
de Boer, Janna N.; Linszen, Mascha M.J.; de Vries, J. Hans; Schutte, Maya J.L.; Begemann, Marieke J.H.; Heringa, Sophie M.; Bohlken, Marc Marijn; Hugdahl, Kenneth; Aleman, André; Wijnen, Frank N.K.; Sommer, Iris Else Clara (Peer reviewed; Journal article, 2019)Background: Studies investigating the underlying mechanisms of hallucinations in patients with schizophrenia suggest that an imbalance in top-down expectations v. bottom-up processing underlies these errors in perception. ... -
Behavioral measures of attention and cognitive control during a new auditory working memory paradigm
Kayser, Jurgen; Wong, Lidia Y X; Sacchi, Elizabeth; Casal-Roscum, Lindsey; Alvarenga, Jorge E; Hugdahl, Kenneth; Bruder, Gerard E; Jonides, John (Peer reviewed; Journal article, 2019-12-03)Proactive control is the ability to manipulate and maintain goal-relevant information within working memory (WM), allowing individuals to selectively attend to important information while inhibiting irrelevant distractions. ... -
Beyond trauma: A multiple pathways approach to auditory hallucinations in clinical and nonclinical populations
Luhrmann, Tanya Marie; Alderson-Day, Ben; Bell, Vaughan; Bless, Josef J; Corlett, Philip; Hugdahl, Kenneth; Jones, Nev; Larøi, Frank; Mosley, Peter; Padmavati, Ramachandran; Peters, Emmanuelle; Powers, Albert R.; Waters, Flavie (Peer reviewed; Journal article, 2019-02-01)That trauma can play a significant role in the onset and maintenance of voice-hearing is one of the most striking and important developments in the recent study of psychosis. Yet the finding that trauma increases the risk ... -
Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study
Tønnesen, Siren; Kaufmann, Tobias; de Lange, Ann-Marie Glasø; Richard, Geneviève; Nhat Trung, Doan; Alnæs, Dag; van der Meer, Dennis; Rokicki, Jaroslav; Moberget, Torgeir; Maximov, Ivan; Agartz, Ingrid; Aminoff, Sofie Ragnhild; Beck, Dani; Barch, Deanna M.; Beresniewicz, Justyna; Cervenka, Simon; Fatouros-Bergman, Helena; Craven, Alexander R.; Flyckt, Lena; Gurholt, Tiril Pedersen; Haukvik, Unn Kristin H.; Hugdahl, Kenneth; Johnsen, Erik; Jönsson, Erik Gunnar; Schizophrenia Project (KaSP), Karolinska; Kolskår, Knut-Kristian; Kroken, Rune Andreas; Lagerberg, Trine Vik; Løberg, Else-Marie; Nordvik, Jan Egil; Sanders, Anne-Marthe; Ulrichsen, Kristine Moe; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Journal article; Peer reviewed, 2020)Background Schizophrenia (SZ) and bipolar disorder (BD) share substantial neurodevelopmental components affecting brain maturation and architecture. This necessitates a dynamic lifespan perspective in which brain aberrations ... -
Children with dyslexia show cortical hyperactivation in response to increasing literacy processing demands
Morken, Frøydis; Helland, Turid; Hugdahl, Kenneth; Specht, Karsten (Peer reviewed; Journal article, 2014-12-22)This fMRI study aimed to examine how differences in literacy processing demands may affect cortical activation patterns in 11- to 12-year-old children with dyslexia as compared to children with typical reading skills. ... -
Combined fMRI Region- and Network-Analysis Reveal New Insights of Top-Down Modulation of Bottom-Up Processes in Auditory Laterality
Kazimierczak, Katarzyna; Craven, Alexander R.; Ersland, Lars; Specht, Karsten; Dumitru, Magda L.; Sandøy, Lydia B.; Hugdahl, Kenneth (Journal article; Peer reviewed, 2022)Dichotic listening along with the right-ear advantage (REA) has been a standard method of investigating auditory laterality ever since it was first introduced into neuropsychology in the early 1960s. Beginning in the 1980s, ... -
Comparison of seven modelling algorithms for γ-aminobutyric acid–edited proton magnetic resonance spectroscopy
Craven, Alexander R.; Bhattacharyya, Pallab K.; Clarke, William T.; Dydak, Ulrike; Edden, Richard A.E.; Ersland, Lars; Mandal, Pravat K.; Mikkelsen, Mark; Murdoch, James B.; Near, Jamie; Rideaux, Reuben; Shukla, Deepika; Wang, Min; Wilson, Martin; Zöllner, Helge J.; Hugdahl, Kenneth; Oeltzschner, Georg (Journal article; Peer reviewed, 2022)Edited MRS sequences are widely used for studying γ-aminobutyric acid (GABA) in the human brain. Several algorithms are available for modelling these data, deriving metabolite concentration estimates through peak fitting ... -
Default-mode network functional connectivity is closely related to metabolic activity
Passow, Susanne; Specht, Karsten; Adamsen, Tom Christian; Biermann, Martin; Brekke, Njål; Craven, Alexander R.; Ersland, Lars; Grüner, Renate; Kleven-Madsen, Nina; Kvernenes, Ole Heine; Schwarzlmüller, Thomas; Olesen, Rasmus Aamand; Hugdahl, Kenneth (Peer reviewed; Journal article, 2015-06)Over the last decade, the brain's default-mode network (DMN) and its function has attracted a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of DMN functional connectivity, or more ... -
Development of Performance and ERPs in a Flanker Task in Children and Adolescents with Tourette Syndrome—A Follow-Up Study
Eichele, Heike; Eichele, Tom; Marquardt, Lynn; Adolfsdottir, Steinunn; Hugdahl, Kenneth; Sørensen, Lin; Plessen, Kerstin J. (Peer reviewed; Journal article, 2017-06-12)Background: Tourette Syndrome (TS) is a neurodevelopmental disorder with childhood-onset, with a typical decline in tic severity, as well as an increasing ability to suppress tics in late childhood and adolescence. These ... -
Dynamic Functional Connectivity Patterns in Schizophrenia and the Relationship With Hallucinations
Weber, Sarah; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Kandilarova, Sevdalina; Stoyanov, Drozdstoy; Kompus, Kristiina; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)There is a wealth of evidence showing aberrant functional connectivity (FC) in schizophrenia but with considerable variability in findings across studies. Dynamic FC is an extension of traditional static FC, in that such ... -
Dynamic up- and down-regulation of thedefault (DMN) and extrinsic (EMN) modenetworks during alternating task-on and task-offperiods
Hugdahl, Kenneth; Kazimierczak, Katarzyna Anna; Beresniewicz, Justyna; Kompus, Kristiina; Westerhausen, René; Ersland, Lars; Grüner, Renate; Specht, Karsten (Peer reviewed; Journal article, 2019)Using fMRI, Hugdahl et al. (2015) reported the existence of a general-domain cortical network during active task-processing which was non-specific to the cognitive task being processed. They labelled this network the ... -
The effects of alcohol intoxication on neuronal activation at different levels of cognitive load
Gundersen, Hilde; Grüner, Renate; Specht, Karsten; Hugdahl, Kenneth (Peer reviewed; Journal article, 2008-08-22)The aim of this study was to investigate how alcohol intoxication at two blood alcohol concentrations (BAC) affected neuronal activation during increasing levels of cognitive load. For this purpose we used functional ... -
Feasibility and Acceptability of Using a Mobile Phone App for Characterizing Auditory Verbal Hallucinations in Adolescents With Early-Onset Psychosis: Exploratory Study
Smelror, Runar; Bless, Josef J; Hugdahl, Kenneth; Agartz, Ingrid (Peer reviewed; Journal article, 2019-05-14)Background: Auditory verbal hallucinations (AVH) are the most frequent symptom in early-onset psychosis (EOP) and a risk factor for increased suicide attempts in adolescents. Increased knowledge of AVH characteristics can ... -
Functional asymmetry and effective connectivity of the auditory system during speech perception is modulated by the place of articulation of the consonant – A 7 T fMRI study
Specht, Karsten; Baumgartner, Florian; Stadler, Jörg; Hugdahl, Kenneth; Pollmann, Stefan (Peer reviewed; Journal article, 2014-06-11)To differentiate between stop-consonants, the auditory system has to detect subtle place of articulation (PoA) and voice-onset time (VOT) differences between stop-consonants. How this differential processing is represented ... -
Functional connectome differences in individuals with hallucinations across the psychosis continuum
Schutte, Maya J. L.; Bohlken, Marc M.; Collin, Guusje; Abramovic, Lucija; Boks, Marco P. M.; Cahn, Wiepke; Dauwan, Meenakshi; van Dellen, Edwin; van Haren, Neeltje E. M.; Hugdahl, Kenneth; Koops, Sanne; Mandl, René C. W.; Sommer, Iris E. C. (Journal article; Peer reviewed, 2021)Hallucinations may arise from an imbalance between sensory and higher cognitive brain regions, reflected by alterations in functional connectivity. It is unknown whether hallucinations across the psychosis continuum exhibit ... -
Glutamate- and GABA-Modulated Connectivity in Auditory Hallucinations—A Combined Resting State fMRI and MR Spectroscopy Study
Weber, Sarah; Hjelmervik, Helene; Craven, Alexander R.; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Ersland, Lars; Kompus, Kristiina; Hugdahl, Kenneth (Journal article; Peer reviewed, 2021)Background: Auditory verbal hallucinations (AVH) have been linked to aberrant interhemispheric connectivity between the left and the right superior temporal gyrus (STG), labeled the interhemispheric miscommunication theory. ... -
How brain asymmetry relates to performance – a large-scale dichotic listening study
Hirnstein, Marco; Hugdahl, Kenneth; Hausmann, Markus (Peer reviewed; Journal article, 2014-01-02)All major mental functions including language, spatial and emotional processing are lateralized but how strongly and to which hemisphere is subject to inter- and intraindividual variation. Relatively little, however, is ... -
Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia
Falkenberg, Liv Eggset; Westerhausen, René; Craven, Alexander R.; Kroken, Rune A.; Løberg, Else-Marie; Specht, Karsten; Hugdahl, Kenneth (Peer reviewed; Journal article, 2014-04-02)Schizophrenia is characterized by impaired cognitive functioning, and brain regions involved in cognitive control processes show marked glutamatergic abnormalities. However, it is presently unclear whether aberrant neuronal ...