Blar i Bergen Open Research Archive på forfatter "Mazzawi, Tarek"
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Abnormal Uroguanylin Immunoreactive Cells Density in the Duodenum of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Changes following Fecal Microbiota Transplantation
Mazzawi, Tarek; Eikrem, Øystein Solberg; Lied, Gülen Arslan; Hausken, Trygve (Journal article; Peer reviewed, 2020)Altered densities of enteroendocrine cells play an important role in patients with irritable bowel syndrome (IBS). Uroguanylin activates guanylate cyclase-C to regulate intestinal electrolyte and water transport. Aim. To ... -
Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation
Mazzawi, Tarek; Hausken, Trygve; El-Salhy, Magdy (Journal article; Peer reviewed, 2022)Objectives The aim was to investigate the effect of fecal microbiota transplantation (FMT) on colonic enteroendocrine cells densities in patients with irritable bowel syndrome (IBS). Materials and methods This study ... -
Changes in the symptom pattern and the densities of large-intestinal endocrine cells following Campylobacter infection in irritable bowel syndrome: a case report
El-Salhy, Magdy; Mazzawi, Tarek; Gundersen, Doris; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2013-09-29)Background Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder. Post-infectious IBS (PI-IBS) is a subset of IBS that accounts for a large proportion of IBS patients. The PI-IBS symptoms ... -
Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
Mazzawi, Tarek; Hausken, Trygve; Hov, Johannes Espolin Roksund; Valeur, Jørgen; Sangnes, Dag André; El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Lied, Gülen Arslan (Peer reviewed; Journal article, 2019)Objectives: Irritable bowel syndrome (IBS) may be associated with disturbances in gut microbiota composition and functions. We recently performed a study of fecal microbiota transplantation (FMT) in diarrhea-predominant ... -
Dietary guidance normalizes large intestinal endocrine cell densities in patients with irritable bowel syndrome
Mazzawi, Tarek; Hausken, Trygve; Gundersen, Doris Irene; El-Salhy, Magdy (Peer reviewed; Journal article, 2015-11-25)Background/Objectives: To determine the large intestinal endocrine cell types affected following dietary guidance in patients with irritable bowel syndrome (IBS). Subjects/Methods: The study included 13 IBS patients and ... -
The Effect of Anaerobically Cultivated Human Intestinal Microbiota Compared to Fecal Microbiota Transplantation on Gut Microbiota Profile and Symptoms of Irritable Bowel Syndrome, a Double-Blind Placebo-Controlled Study
Mazzawi, Tarek; Hausken, Trygve; Hatlebakk, Jan Gunnar; Refsnes, Per; Lied, Gülen Arslan (Journal article; Peer reviewed, 2022)Fecal microbiota transplantation (FMT) from healthy donors has been shown to improve the symptoms of irritable bowel syndrome (IBS) and changes the profile of the gut microbiota for the recipients. Alternatively, anaerobically ... -
Effect of dietary management on the gastric endocrine cells in patients with irritable bowel syndrome
Mazzawi, Tarek; Hausken, Trygve; Gundersen, Doris; El-Salhy, Magdy (Peer reviewed; Journal article, 2014-08-06)Background/objectives: The gastric endocrine cells in patients with irritable bowel syndrome (IBS) tend to normalize following dietary guidance. The aim of the present study was to identify the gastric endocrine cell types ... -
Effects of dietary guidance on the symptoms, quality of life and habitual dietary intake of patients with irritable bowel syndrome
Mazzawi, Tarek; Hausken, Trygve; Gundersen, Doris Irene; El-Salhy, Magdy (Peer reviewed; Journal article, 2013-09)Diet is important in triggering the symptoms of irritable bowel syndrome (IBS). This study investigated the impact of dietary guidance on the symptoms, quality of life and habitual diet of patients with IBS. Forty‑six ... -
The Effects of Fecal Microbiota Transplantation on the Symptoms and the Duodenal Neurogenin 3, Musashi 1, and Enteroendocrine Cells in Patients With Diarrhea-Predominant Irritable Bowel Syndrome
Mazzawi, Tarek; El-Salhy, Magdy; Lied, Gülen Arslan; Hausken, Trygve (Journal article; Peer reviewed, 2021)Introduction: Interactions between the gut microbiota and enteroendocrine cells play important role in irritable bowel syndrome (IBS). Reduced stem cell densities and their differentiation into enteroendocrine cells may ... -
The fecal microbiota transplantation response differs between patients with severe and moderate irritable bowel symptoms
El-Salhy, Magdy; Mazzawi, Tarek; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2022)Objectives: Fecal microbiota transplantation (FMT) is a promising intervention for patients with irritable bowel syndrome (IBS). The present study aimed to identify any differences in FMT response between patients with ... -
Gastric emptying of low- and high-caloric liquid meals measured using ultrasonography in healthy volunteers
Mazzawi, Tarek; Bartsch, Emily; Benammi, Sara; Ferro, Rosa Maria Carrasco; Nikitina, Ekaterina; Nimer, Nancy; Ortega, Lara Jiménez; Perrotte, Charles; Pithon, Joäo Vitor; Rosalina, Safira; Sharp, Alexis; Stevano, Reza; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2019-01-07)Purpose Delayed gastric emptying is present in patients with functional dyspepsia (FD), diabetes mellitus, and neurological diseases. Diet may affect gastric emptying symptoms in patients with FD. We sought to determine ... -
Increased chromogranin A cell density in the large intestine of patients with irritable bowel syndrome after receiving dietary guidance
Mazzawi, Tarek; Gundersen, Doris Irene; Hausken, Trygve; El-Salhy, Magdy (Peer reviewed; Journal article, 2015)The large intestine contains five types of endocrine cells that regulate its functions by sensing its luminal contents and releasing specific hormones. Chromogranin A (CgA) is a common marker for the gastrointestinal ... -
Increased gastric chromogranin A cell density following changes to diets of patients with irritable bowel syndrome
Mazzawi, Tarek; Gundersen, Doris; Hausken, Trygve; El-Salhy, Magdy (Peer reviewed; Journal article, 2014-11)The gut endocrine cells control and regulate several functions of the gastrointestinal tract. They have been reported to be abnormal in irritable bowel syndrome (IBS), with alterations occurring in several functions regulated ... -
Irritable bowel syndrome patients who are not likely to respond to fecal microbiota transplantation
El-Salhy, Magdy; Mazzawi, Tarek; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2022)Background Fecal microbiota transplantation (FMT) interventions have recently been advocated to not succeed in every irritable bowel syndrome (IBS) patient, since the outcome of FMT varies with the IBS subset. This study ... -
The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
Mazzawi, Tarek; Lied, Gülen Arslan; Sangnes, Dag André; El-Salhy, Magdy; Hov, Johannes Espolin Roksund; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2018-11-14)Background: Gut microbiota alterations are important in irritable bowel syndrome (IBS). The aim was to investigate the effect of fecal microbiota transplantation (FMT) on gut microbiota and the symptoms in patients with ... -
The Role of Diet in Irritable Bowel Syndrome with special reference to Gut Neuroendocrine System
Mazzawi, Tarek (Doctoral thesis, 2015-08-28)Background: The majority of the patients with irritable bowel syndrome (IBS) believe that diet triggers their symptoms, which affect the quality of their lives. The pathophysiology of IBS is not exactly known, however, the ...