Browsing Bergen Open Research Archive by Author "Neppelberg, Evelyn"
Now showing items 1-9 of 9
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Granulocyte macrophage-colony stimulating factor and keratinocyte growth factor control of early stages of differentiation of oral epithelium
Das, Ridhima; Virlan, Maria Justina Roxana; Xenaki, Victoria; Kulasekara, Keerthi Kumara; Lukandu, Ochiba Mohammed; Neppelberg, Evelyn; Vintermyr, Olav Karsten; Johannessen, Anne Christine; Calenic, Bogdan; Costea, Daniela Elena (Journal article; Peer reviewed, 2022)Oral epithelial differentiation is known to be directed by underlying fibroblasts, but the responsible factor(s) have not been identified. We aimed here to identify fibroblast-derived factors responsible for oral epithelial ... -
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
Parajuli, Himalaya; Teh, Muy-Teck; Abrahamsen, Siren; Christoffersen, Ingeborg Monge; Neppelberg, Evelyn; Lybak, Stein; Osman, Tarig Al-Hadi; Johannessen, Anne Christine; Gullberg, Donald; Skarstein, Kathrine; Costea, Daniela Elena (Peer reviewed; Journal article, 2017-04)BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ... -
Isolation and characterization of cells derived from human epithelial rests of Malassez
Kitajima, Kayoko; Das, Ridhima; Liang, Xiao; Neppelberg, Evelyn; Johannessen, Anne Christine; Costea, Daniela Elena; Igarashi, Masaru (Journal article; Peer reviewed, 2019)The epithelial rests of Malassez (ERMs) might represent a valuable source of oral epithelial cells with stem cell properties. The purpose of this study was to isolate and characterize cells derived from human ERM, and ... -
MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells
Rajthala, Saroj; Parajuli, Himalaya; Dongre, Harsh Nitin; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Sapkota, Dipak; Johannessen, Anne Christine; Costea, Daniela Elena (Journal article; Peer reviewed, 2022-03-17)Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ... -
Nano-TiO2 penetration of oral mucosa: in vitro analysis using 3D organotypic human buccal mucosa models
Konstantinova, Victoria; Ibrahim, Mohamed; Lie, Stein Atle; Birkeland Salmorin, Eivind; Neppelberg, Evelyn; Marthinussen Cuida, Mihaela; Costea, Daniela Elena; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2016)BACKGROUND: Oral cavity is a doorway for a variety of products containing titanium dioxide (TiO2) nanoparticles (NPs) (nano-TiO2) such as food additives, oral healthcare products and dental materials. Their potential to ... -
Pathological mechanisms in oral lichen planus : a atudy of apoptosis - regulatory proteins and risk markers for malignant transformation
Neppelberg, Evelyn (Doctoral thesis, 2007-05-04)Oral lichen planus (OLP) is a chronic mucocutaneous disease characterized by basal cell destruction and a subepithelial band-like mononuclear inflammatory cell infiltrate predominated by T cells. Molecular biological changes ... -
Patient experience following iliac crest alveolar bone gradfting av implant replacement
Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Gjengedal, Harald; Shanbhag, Siddharth; Neppelberg, Evelyn (Journal article; Peer reviewed, 2020-02-05)Background The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment ... -
Profiling and functional analysis of microRNA deregulation in cancer-associated fibroblasts in oral squamous cell carcinoma depicts an anti-invasive role of microRNA-204 via regulation of their motility
Rajthala, Saroj; Min, Anjie; Parajuli, Himalaya; Debnath, Kala Chand; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Vintermyr, Olav Karsten; Johannessen, Anne Christine; Sapkota, Dipak; Costea, Daniela Elena (Journal article; Peer reviewed, 2021-11-04)Background: Knowledge on the role of miR changes in tumor stroma for cancer progression is limited. This study aimed to investigate the role of miR dysregulation in cancer-associated fibroblasts (CAFs) in oral squamous ... -
Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.
Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak; Neppelberg, Evelyn; Lybak, Stein; Liavaag, Per Gunnar; Johannessen, Anne Christine; Jacobsen, Hege Karine; Enger, Per Øyvind; Costea, Daniela Elena; Wang, Jian (Peer reviewed; Journal article, 2014-12)Background: Although several approaches for identification and isolation of carcinoma cells with tumour initiating properties have been established, enrichment of a population of pure and viable tumour-initiating cells ...