Siste dokument

  • A longitudinal study of dental erosion and associated lifestyle factors in a group of Swedish children and adolescents 

    Hasselkvist, Agneta (The University of Bergen, 2017-12-15)
    Background: Erosive wear has been observed among Swedish adolescents, but with unknown prevalence. High prevalence of dental erosion is reported from different parts of the world, and often linked to an increasing ...
    Doctoral thesis
  • Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016 

    Naghavi, Mohsen; Abajobir, Amanuel Alemu; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw Ferede; Aboyans, Victor; Adetokunboh, Olatunji; Ärnlöv, Johan; Afshin, Ashkan; Agrawal, Anurag; Kiadaliri, Aliasghar Ahmad; Ahmadi, Alireza; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Aiyar, Sneha; Al-Eyadhy, Ayman; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alene, Kefyalew Addis; Ali, Syed Danish; Alizadeh-Navaei, Reza; Alkaabi, Juma M.; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Allen, Christine; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Amini, Erfan; Ammar, Walid; Amoako, Yaw Ampem; Anber, Nahla; Andersen, Hjalte H.; Andrei, Catalina Liliana; Androudi, Sofia; Ansari, Hossein; Antonio, Carl Abelardo T.; Anwari, Palwasha; Arora, Megha; Artaman, Al; Aryal, Krishna Kumar; Asayesh, Hamid; Asgedom, Solomon W.; Atey, Tesfay Mehari; Avila-Burgos, Leticia; Avokpaho, Euripide Frinel G. Arthur; Awasthi, Ashish; Ellingsen, Christian Lycke; Hailu, Alemayehu; Knudsen, Ann Kristin; Vollset, Stein Emil; Weiderpass, Elisabete (Elsevier, 2017-09)
    Background: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive ...
    Journal article
  • Perioperative hemodynamics and risk for delirium and new onset dementia in hip fracture patients; A prospective follow-up study 

    Neerland, Bjørn Erik; Krogseth, Maria; Juliebø, Vibeke; Ranhoff, Anette Hylen; Engedal, Knut; Frihagen, Frede Jon; Ræder, Johan; Wyller, Torgeir Bruun; Watne, Leiv Otto (PLOS, 2017-07-10)
    Background Delirium is common in hip fracture patients and many risk factors have been identified. Controversy exists regarding the possible impact of intraoperative control of blood pressure upon acute (delirium) and long ...
    Journal article
  • Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients 

    Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard (BioMed Central, 2017-11-28)
    Background: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement ...
    Journal article
  • Implication of the APP gene in intellectual abilities 

    Myrum, Craig; Nikolaienko, Oleksii; Bramham, Clive R.; Haavik, Jan; Zayats, Tetyana (IOS Press, 2017)
    Background: Cognitive functions are highly heritable and polygenic, though the source of this genetic influence is unclear. On the neurobiological level, these functions rely on effective neuroplasticity, in which the ...
    Journal article
  • Polygenic overlap between C-reactive protein, plasma lipids, and Alzheimer disease 

    Desikan, Rahul S.; Schork, Andrew J.; Wang, Yunpeng; Thompson, Wesley K.; Dehghan, Abbas; Ridker, Paul M.; Chasman, Daniel I.; McEvoy, Linda K.; Holland, Dominic; Chen, Chi-Hua; Karow, David S.; Brewer, James B.; Hess, Christopher P.; Williams, Julie; Sims, Rebecca; O'Donovan, Michael C.; Choi, Seung Hoan; Bis, Joshua C.; Ikram, M. Arfan; Gudnason, Vilmundur; DeStefano, Anita L.; Van Der Lee, Sven J.; Psaty, Bruce M.; Van Duijn, Cornelia M.; Launer, Lenore; Seshadri, Sudha; Pericak-Vance, Margaret A.; Mayeux, Richard; Haines, Jonathan L.; Farrer, Lindsay A.; Hardy, John; Ulstein, Ingun; Aarsland, Dag; Fladby, Tormod; White, Linda; Sando, Sigrid Botne; Rongve, Arvid; Witoelar, Aree; Djurovic, Srdjan; Hyman, Bradley T.; Snædal, Jon; Steinberg, Stacy; Stefansson, Hreinn; Stefánsson, Kári; Schellenberg, Gerard D.; Andreassen, Ole Andreas; Dale, Anders (American Heart Association, Inc., 2015-06)
    Background—Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood. We investigated whether this ...
    Journal article
  • Health in the aftermath of a malodorous chemical explosion: Subjective health complaints and post-traumatic stress symptoms among workers 

    Tjalvin, Gro (The University of Bergen, 2018-02-02)
    Background: A chemical explosion in an oil tank took place in an industrial harbour area in Norway, in May 2007. Nobody was killed in the accident, but a malodorous environmental pollution was emitted, and spread in the ...
    Doctoral thesis
  • Health complaints after a malodorous chemical explosion: a longitudinal study 

    Tjalvin, Gro; Lygre, Stein Håkon Låstad; Hollund, Bjørg Eli; Moen, Bente Elisabeth; Bråtveit, Magne (Oxford University Press, 2015)
    Background: Physical and psychological symptoms are prevalent in populations recently affected by industrial accidents. Follow-up studies of human health effects are scarce, and as most of them focus on residents, little ...
    Journal article
  • Odour as a determinant of persistent symptoms after a chemical explosion, a longitudinal study 

    Tjalvin, Gro; Magerøy, Nils; Bråtveit, Magne; Lygre, Stein Håkon Låstad; Hollund, Bjørg Eli; Moen, Bente Elisabeth (National Institute of Occupational Safety and Health, 2017)
    Foul-smelling environmental pollution was a major concern following a chemical workplace explosion. Malodorous pollution has previously been associated with aggravated physical and psychological health, and in persons ...
    Journal article
  • Cerebral magnetic resonance imaging in children with prenatal drug exposure. Structural and functional aspects of the opioid-exposed brain 

    Sirnes, Eivind (The University of Bergen, 2018-02-02)
    Background: Over the last few decades brain imaging studies have made important contributions to our understanding of how prenatal drug exposure can impact normal brain development. The teratogenic potential of alcohol has ...
    Doctoral thesis
  • Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 

    Gakidou, Emmanuela; Afshin, Ashkan; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Abu-Rmeileh, Niveen M. E.; Abyu, Gebre Yitayih; Adedeji, Isaac Akinkunmi; Adetokunboh, Olatunji; Afarideh, Mohsen; Agrawal, Anurag; Agrawal, Sutapa; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Akinyemi, Rufus Olusola; Akseer, Nadia; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alasfoor, Deena; Alene, Kefyalew Addis; Ali, Komal; Alizadeh-Navaei, Reza; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Amini, Erfan; Ammar, Walid; Amoako, Yaw Ampem; Ansari, Hossein; Anto, Josep M.; Antonio, Carl Abelardo T.; Anwari, Palwasha; Arian, Nicholas; Arnlov, Johan; Artaman, A.; Aryal, Krishna Kumar; Kisa, Adnan; Knudsen, Ann Kristin; Vollset, Stein Emil; Norheim, Ole Frithjof; Tollånes, Mette Christophersen; Weiderpass, Elisabete (Elsevier, 2017-09)
    METHODS: We used the comparative risk assessment framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), ...
    Journal article
  • Our genes, our selves: hereditary breast cancer and biological citizenship in Norway 

    Solbrække, Kari Nyheim; Søiland, Håvard; Lode, Kirsten; Gripsrud, Birgitta Haga (Springer, 2017-03)
    In this paper we explore the rise of ‘the breast cancer gene’ as a field of medical, cultural and personal knowledge. We address its significance in the Norwegian public health care system in relation to so-called biological ...
    Journal article
  • Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 

    Hay, Simon I.; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abebo, Teshome Abuka; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Ackerman, Ilana N.; Aryal, Krishna Kumar; Hailu, Alemayehu; Htet, Aung Soe; Knudsen, Ann Kristin; Kisa, Adnan; Norheim, Ole Frithjof; Skirbekk, Vegard Fykse; Vollset, Stein Emil; Weiderpass, Elisabete (Elsevier, 2017-09)
    METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 ...
    Journal article
  • GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation 

    Gozdz, Agata; Nikolaienko, Oleksii; Urbanska, Malgorzata; Cymerman, Iwona; Sitkiewicz, Ewa; Blazejczyk, Magdalena; Dadlez, Michal; Bramham, Clive R.; Jaworski, Jacek (Frontiers, 2017-06-16)
    The selective and neuronal activity-dependent degradation of synaptic proteins appears to be crucial for long-term synaptic plasticity. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which ...
    Journal article
  • Exposure to mycophenolate and fatherhood 

    Midtvedt, Karsten; Bergan, Stein; Reisæter, Anna Varberg; Vikse, Bjørn Egil; Åsberg, Anders (Wolters Kluwer, 2017-07)
    Background: Mycophenolic acid (MPA) is the active immunosuppressive substance in both mycophenolate mofetil and mycophenolate sodium, and it is widely used after organ transplantation. In women, taking MPA is teratogenic ...
    Journal article
  • Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia 

    Urbaneja, María A.; Skjærven, Lars; Aubi Catevilla, Oscar; Underhaug, Jarl; López, David J.; Arregi, Igor; Alonso-Mariño, Marián; Cuevas, Andoni; Rodríguez, José A.; Martinez, Aurora; Bañuelos, Sonia (Nature Publishing Group, 2017-10-24)
    Nucleophosmin (NPM) is a nucleolar protein involved in ribosome assembly and cell homeostasis. Mutations in the C-terminal domain of NPM that impair native folding and localization are associated with acute myeloid leukemia ...
    Journal article
  • The influence of birth weight and length on bone mineral density and content in adolescence: The Tromsø Study, Fit Futures 

    Christoffersen, Tore; Ahmed, Luai A.; Daltveit, Anne Kjersti; Dennison, Elaine; Evensen, Elin; Furberg, Anne-Sofie; Gracia-Marco, Luis; Grimnes, Guri; Nilsen, Ole-Andreas; Schei, Berit; Tell, Grethe S.; Vlachopoulous, Dimitris; Winther, Anne; Emaus, Nina (Springer, 2017-12)
    Summary: The influence of birth weight and length on bone mineral parameters in adolescence is unclear. We found a positive association between birth size and bone mineral content, attenuated by lifestyle factors. This ...
    Journal article
  • Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo 

    Nair Raveendran, Rajeevkumar; Patil, Sudarshan; Tiron, Adrian; Kanhema, Tambudzai; Panja, Debabrata; Schiro, Lars Erik; Parobczak, Kamil; Wilczynski, Grzegorz M; Bramham, Clive R. (Frontiers, 2017-05-10)
    Activity-regulatedcytoskeleton-associated protein (Arc) protein is implicated as a master regulator of long-term forms of synaptic plasticity and memory formation, but the mechanisms controlling Arc protein function are ...
    Journal article
  • Effect of nerve injury on the number of dorsal root ganglion neurons and autotomy behavior in adult Bax-deficient mice 

    Lyu, Chuang; Lyu, Gong-Wei; Martinez, Aurora; Shi, Tie-Jun (Dove Press, 2017-08-30)
    Background: The proapoptotic molecule BAX, plays an important role in mitochondrial apoptotic pathway. Dorsal root ganglion (DRG) neurons depend on neurotrophic factors for survival at early developmental stages. Withdrawal ...
    Journal article
  • Resection rates and predictors of survival after surgery for colorectal liver metastases 

    Angelsen, Jon-Helge (The University of Bergen, 2017-10-20)
    Introduction: Occurrence of liver metastases is common following colorectal cancer (CRC), and resection is the only option with a potential for cure offered to a minor part of these patients. During the last decades ...
    Doctoral thesis

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