Faculty of Medicine
Underarkiv i dette arkivet
Samlinger i dette arkivet
Siste dokument
-
Therapeutic potential and challenges of natural killer cells in treatment of solid tumors
(Frontiers, 2015-04-29)Natural killer (NK) cells are innate lymphoid cells that hold tremendous potential for effective immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring one-to-one target engagement and ...Journal article -
High-Intensity Interval Training in Patients with Heart Failure with Reduced Ejection Fraction
(Wolters Kluwer, 2017-02)Background: Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart ...Journal article -
Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: A prospective observational study
(BioMed Central, 2017-02-02)Background: The occurrence of bloodstream infection (BSI) and antimicrobial resistance have been increasing in many countries. We studied trends in antimicrobial resistance and empiric antibiotic therapy at a medium-sized ...Journal article -
Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study
(BioMed Central, 2017-03-11)Background: Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods: We studied the burden of disease and death related to BSI in a ...Journal article -
Insulin and GSK3β-inhibition abrogates the infarct sparing-effect of ischemic postconditioning in ex vivo rat hearts
(Taylor & Francis, 2017)Objectives. Pharmacological treatment of reperfusion injury using insulin and GSK3β inhibition has been shown to be cardioprotective, however, their interaction with the endogenous cardioprotective strategy, ischemic ...Journal article -
The PRoteomics IDEntification (PRIDE) Converter 2 Framework: An Improved Suite of Tools to Facilitate Data Submission to the PRIDE Database and the ProteomeXchange Consortium
(ASBMB, 2012-12)The original PRIDE Converter tool greatly simplified the process of submitting mass spectrometry (MS)-based proteomics data to the PRIDE database. However, after much user feedback, it was noted that the tool had some ...Journal article -
DeNovoGUI: an open source graphical user interface for de novo sequencing of tandem mass spectra
(American Chemical Society, 2014)De novo sequencing is a popular technique in proteomics for identifying peptides from tandem mass spectra without having to rely on a protein sequence database. Despite the strong potential of de novo sequencing algorithms, ...Journal article -
In-depth characterization of the cerebrospinal fluid (CSF) proteome displayed through the CSF proteome resource (CSF-PR)
(ASBMB, 2014-11)In this study, the human cerebrospinal fluid (CSF) proteome was mapped using three different strategies prior to Orbitrap LC-MS/MS analysis: SDS-PAGE and mixed mode reversed phase-anion exchange for mapping the global CSF ...Journal article -
Associations between fish intake and the metabolic syndrome and its components among middle-aged men and women: the Hordaland Health Study
(Taylor & Francis, 2017)In epidemiologic studies, the relationship between fish consumption and the metabolic syndrome (MetS) have been inconclusive and sex differences reported. The aim was to investigate associations between fish intake and the ...Journal article -
thermo-msf-parser: An Open Source Java Library to Parse and Visualize Thermo Proteome Discoverer msf Files
(American Chemical Society, 2011)The Thermo Proteome Discoverer program integrates both peptide identification and quantification into a single workflow for peptide-centric proteomics. Furthermore, its close integration with Thermo mass spectrometers has ...Journal article -
Effects of external inspection on sepsis detection and treatment: a study protocol for a quasiexperimental study with a stepped-wedge design
(BMJ, 2017)Introduction: Inspections are widely used in health care as a means to improve the health services delivered to patients. Despite their widespread use, there is little evidence of their effect. The mechanisms for how ...Journal article -
Use of stable isotope dimethyl labeling coupled to selected reaction monitoring to enhance throughput by multiplexing relative quantitation of targeted proteins
(American Chemical Society, 2012)In this manuscript, we present a proof-of-concept study for targeted relative protein quantitation workflow using chemical labeling in the form of dimethylation, coupled with selected reaction monitoring (dimethyl-SRM). ...Journal article -
Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015
(Elsevier, 2017-07)Background: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). ...Journal article -
Regulation and quantification of cellular mitochondrial morphology and content
(Bentham Science, 2014)Mitochondria play a key role in signal transduction, redox homeostasis and cell survival, which extends far beyond their classical functioning in ATP production and energy metabolism. In living cells, mitochondrial content ...Journal article -
Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway
(BMJ, 2017)Objective: This paper aims to study if vaginal breech delivery is associated with increased risk for neonatal mortality (NNM) or cerebral palsy (CP) in Norway where vaginal delivery accounts for 1/3 of all breech ...Journal article -
Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)
(Elsevier, 2013-01)The hypolipidemic effect of peroxisome proliferator-activated receptor (PPAR) activators has been explained by increasing mitochondrial fatty acid oxidation, as observed in livers of rats treated with the pan-PPAR activator ...Journal article -
A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer
(Elsevier, 2016-12)Background: The primary aim of our study was to evaluate the safety and potential toxicity of gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer patients. The secondary aim was to ...Journal article -
Attention-deficit/hyperactivity disorder in offspring of mothers with inflammatory and immune system diseases
(Elsevier, 2017-03)Background: Prenatal inflammatory mechanisms may play a role in the pathogenesis of psychiatric disorders and could be relevant for attention-deficit/hyperactivity disorder (ADHD). We investigated maternal chronic somatic ...Journal article -
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study
(Cambridge University Press, 2013-02)Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free ...Journal article -
High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph
(American Heart Association, 2017-04)The common notion is that the body Na+ is maintained within narrow limits for fluid and blood pressure homeostasis. Several studies have, however, shown that considerable amounts of Na+ can be retained or removed from the ...Journal article
