Faculty of Medicine
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Graft fixation influences revision risk after ACL reconstruction with hamstring tendon autografts : A study of 38,666 patients from the Scandinavian knee ligament registries 2004–2011
(Taylor & Francis, 2018)Background and purpose — A large number of fi xation methods of hamstring tendon autograft (HT) are available for anterior cruciate ligament reconstruction (ACLR). Some studies report an association between fi xation ...Journal article -
Similar migration in computer-assisted and conventional total knee arthroplasty
(Taylor & Francis, 2017)Background and purpose — Computer-assisted surgery (CAS) in total knee arthroplasty (TKA) has been used in recent years in the hope of improving the alignment and positioning of the implant, thereby achieving a better ...Journal article -
Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences
(American Association for Cancer Research, 2016-12)Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of ...Journal article -
The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons
(Society for Neuroscience, 2017-11)Brain-derived neurotrophic factor (BDNF) is an important mediator of long-term synaptic potentiation (LTP) in the hippocampus. The local effects of BDNF depend on the activation of translation activity, which requires the ...Journal article -
FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis
(Springer, 2017-04)Purpose: Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...Journal article -
A short endoscopic Secretin test for the diagnosis of chronic pancreatitis
(The University of Bergen, 2018-06-12)Background: The diagnosis of CP is not yet clearly defined. Many national guidelines exist, but - as in many other not clearly defined diseases - there is no worldwide consensus. In CP, evaluation of exocrine pancreatic ...Doctoral thesis -
Cancer-Associated troke: The Bergen NORSTROKE Study
(Karger, 2015-10-13)Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of ...Journal article -
Risk factors influencing long-term survival and nursing home placement in stroke survivors and patients with carotid stenosis
(The University of Bergen, 2018-01-11)Risk factors influencing long-term survival and nursing home placement in stroke survivors and patients with carotid stenosis Stroke is one of the leading causes of mortality and morbidity worldwide and one of the most ...Doctoral thesis -
Cancer-Associated Ischemic Stroke: The Bergen NORSTROKE Study
(The University of Bergen, 2018-05-25)Background: Stroke and cancer are both leading causes of death and disability in the Western world. Cancer can lead to a hypercoagulable state that can cause ischemic stroke. Mechanisms include disturbance of the coagulation ...Doctoral thesis -
The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
(The University of Bergen, 2016-05-09)Aging is the critical risk factor for many forms of cancer. We used the mammary gland as a model system to study the impact of age on human epithelia in which age is the greatest risk factor for cancer. Dysfunctional ...Doctoral thesis -
High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia
(Cell Press, 2018-04)Aging is associated with tissue-level changes in cellular composition that are correlated with increased susceptibility to disease. Aging human mammary tissue shows skewed progenitor cell potency, resulting in diminished ...Journal article -
Smoking among pregnant women in Norway. Prevalence, self-report validity, and associations to SGA and “early programming” using family and sibling design
(The University of Bergen, 2018-04-27)Background: Although a decline in smoking prevalence is seen in most developed countries, smoking during pregnancy remains an important public health concern, affecting both the mothers’ own health as well as that ...Doctoral thesis -
Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy
(Springer, 2016)Background: The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: ...Journal article -
Evaluation of a guided self-help intervention for irritable bowel syndrome - An interdisciplinary approach
(The University of Bergen, 2017-12-16)Background: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, defined by recurrent abdominal pain or discomfort, associated with defecation and/or altered bowel habits. Due to the lack ...Master thesis -
Randomized Controlled Trial of Extended Perioperative Counseling in Enhanced Recovery After Colorectal Surgery
(Wolters Kluwer, 2018-06)BACKGROUND: Enhanced recovery after surgery programs reduce the length of hospital stay in patients who undergo elective colorectal resection, but the reasons for this reduction are not well understood. OBJECTIVE: The aim ...Journal article -
Prevention and treatment of cardiovascular disease in Ethiopia saves more than lives: cost-effectiveness analysis, extended cost-effectiveness analysis, and financial risk protection
(The University of Bergen, 2018-02-09)Introduction: The burden from cardiovascular disease (CVD) and its risk factors is growing in Ethiopia, especially in urban areas. Yet, the coverage of effective strategies towards its successful control is low. In the ...Doctoral thesis -
Out-of-pocket expenditures for prevention and treatment of cardiovascular disease in general and specialised cardiac hospitals in Addis Ababa, Ethiopia: a cross-sectional cohort study
(BMJ, 2017)Background: Cardiovascular disease poses a great financial risk on households in countries without universal health coverage like Ethiopia. This paper aims to estimate the magnitude and intensity of catastrophic health ...Journal article -
The role of PTEN, PI3K-Akt-mTOR signaling and pseudogene PTENP1 in breast cancer
(The University of Bergen, 2018-04-19)Background: Breast cancer is the most common type of cancer in women, and a major cause of premature death still today. The PI3K-Akt-mTOR signaling (in short: PI3K signaling) pathway is a growth and pro-survival pathway, ...Doctoral thesis -
Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines
(Impact Journals, 2017-04-17)Anthracyclines are key components of human breast cancer chemotherapy. Here, we explored the role of Akt signaling in anthracycline resistance. The antitumor activity of doxorubicin and Akt inhibitor A-443654 alone or ...Journal article -
High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function
(Springer, 2017)Purpose: PTEN is an important tumor suppressor in breast cancer. Here, we examined the prognostic and predictive value of PTEN and PTEN pseudogene (PTENP1) gene expression in patients with locally advanced breast cancer ...Journal article
