Faculty of Medicine
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Water-soluble fish protein intake led to lower serum and liver cholesterol concentrations in obese zucker fa/fa rats
(MDPI, 2018-05-01)Proteins from different fish species and different raw materials such as fish fillets and by-products have shown promising cardioprotective effects in rodents and humans, including effects on cholesterol metabolism. Blue ...Journal article -
Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
(MDPI, 2017-05-18)Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial ...Journal article -
Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
(Nature Publishing Group, 2018-05-02)Schizophrenia is a serious psychotic disorder with high heritability. Several common genetic variants, rare copy number variants and ultra-rare gene-disrupting mutations have been linked to disease susceptibility, but there ...Journal article -
Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes
(Oxford University Press, 2018-04)Background Our objective was to examine the associations of parental body mass index (BMI) and maternal gestational weight gain with childhood-onset type 1 diabetes. Comparing the associations of maternal and paternal BMI ...Journal article -
Clinical decision making in cancer care: a review of current and future roles of patient age
(BioMed Central, 2018-05-09)Background: Patient age is among the most controversial patient characteristics in clinical decision making. In personalized cancer medicine it is important to understand how individual characteristics do affect practice ...Journal article -
Virtual Reality training for patients with non-specific persistent low back pain and pain-related fear of movement: A single-subject experimental study
(The University of Bergen, 2018-11-17)Introduction: Non-specific persistent low back pain is one of the most prevalent musculoskeletal conditions in modern society. A growing body of evidence shows graded exposure therapy is the most preferable treatment to ...Master thesis -
Primary aldosteronism in Western Norway. Studies of diagnostic approach and treatment outcome
(The University of Bergen, 2018-09-06)Primary aldosteronism (PA) is the most common cause of secondary hypertension (HT), accounting for 5 to 12% of all hypertensive individuals. Patients with PA experience increased cardiovascular, renal and metabolic ...Doctoral thesis -
Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism
(Bioscientifica, 2018-03)Background: Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively ...Journal article -
Transcapillary fluid balance in children. Methodology and new clinical studies. To the interstitial space - and back again
(The University of Bergen, 2016-04-29)Objective: The capillaries represent a semipermeable barrier between the blood and the interstitium, where there is a continuous exchange of fluid and solutes. Numerous factors affect the tight regulation of this movement ...Doctoral thesis -
Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: an open, longitudinal, observational study
(BioMed Central, 2018-02-23)Background: Therapeutic hypothermia is neuroprotective in asphyxiated neonates by counteracting mechanisms contributing to brain injury. Although an initial increased permeability is part of an inflammatory reaction ...Journal article -
Interstitial Fluid Colloid Osmotic Pressure in Healthy Children
(Public Library of Science, 2015-04-08)Objective: The colloid osmotic pressure (COP) of plasma and interstitial fluid play important roles in transvascular fluid exchange. COP values for monitoring fluid balance in healthy and sick children have not been ...Journal article -
Limited Benefit of Fish Consumption on Risk of Hip Fracture among Men in the Community-Based Hordaland Health Study
(MDPI, 2018-07-06)Hip fractures have a high prevalence worldwide. Few studies have investigated whether fish consumption is associated with risk of hip fractures. The objective of the present study was to investigate the effect of fish ...Journal article -
Dietary predictors of bone mineral density, hip fractures, mobility and muscle strength - in community-dwelling older persons
(The University of Bergen, 2018-10-23)Background: The aging process involves decline of both muscle and bone mass. The loss of muscle mass is associated with decreased muscle strength and mobility, while loss of bone mass leads to osteoporosis and increased ...Doctoral thesis -
Characterization of the renal function in Epac1 (RapGef3) knockout mice
(The University of Bergen, 2014-06-03)The discovery of the exchange proteins directly activated by cAMP (Epac) has renewed our knowledge of intracellular cAMP signaling. The Epac1 isoform (RapGef3) shows high expression level in the kidney. In vitro studies ...Master thesis -
En undersøkelse av brentkalks effekt på frittlevende stadier av lakselus, og om virkningen har en sammenheng med partikkelstørrelse og reaktivitet, T60
(The University of Bergen, 2018-08-31)I Norge gir lakselusen ( Lepeophtheirus salmonis) alene tap på flere hundre millioner kroner hvert år for lakseoppdretterne på grunn av dødelighet, tap av tilvekst, samt nedgradering av kvalitet og utgifter til behandling ...Master thesis -
The in vivo effect of integrin α11-deficiency and PDGFR inhibition in breast cancer
(The University of Bergen, 2018-10-19)Background: The tumor microenvironment is a major contributor to breast cancer progression. The abnormal composition of the extracellular matrix and its deregulated interactions with stromal cells, which is ...Master thesis -
Chronic disease among women in a resource-constrained setting. The case of pelvic organ prolapse in rural Ethiopia
(The University of Bergen, 2018-10-08)Background: Pregnancy and childbirth are major risk factors for pelvic floor disorders worldwide. Many of the affected women live in resource-constrained settings with high fertility rates, early-age deliveries and limited ...Doctoral thesis -
Life after pelvic organ prolapse surgery: a qualitative study in Amhara region, Ethiopia
(BioMed Central, 2018-05-29)Background: Women living in resource constrained settings often have limited knowledge of and access to surgical treatment for pelvic organ prolapse. Additionally, little is known about experiences during recovery periods or ...Journal article -
An evolutionary epigenetics approach to schizophrenia
(The University of Bergen, 2018-09-28)Schizophrenia is a psychotic disorder with an estimated lifetime prevalence of ~1% worldwide. Despite reduced fecundity of patients, this rate is stable across population groups separated by geography and time. There is ...Doctoral thesis -
Recently evolved human-specific methylated regions are enriched in schizophrenia signals
(BioMed Central, 2018)Background: One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution. This hypothesis is supported by evidence suggesting that ...Journal article
