Browsing Department of Clinical Medicine by Author "Aunan, Jan Rune"
Now showing items 1-4 of 4
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The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks
Aunan, Jan Rune; Cho, William C; Søreide, Kjetil (Peer reviewed; Journal article, 2017-10)Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development. Due to advances in health care, hygiene control and food availability, life expectancy is ... -
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis
Søreide, Kjetil; Roalsø, Marcus Thomas Thor; Aunan, Jan Rune (Journal article; Peer reviewed, 2020)Purpose: Pancreatic cancer is one of the most lethal of solid tumors and is associated with aggressive cancer biology. The purpose is to review the role of trypsin and effect on molecular and cellular processes potentially ... -
Observation or resection of pancreatic intraductal papillary mucinous neoplasm: An ongoing tug of war
Aunan, Jan Rune; Jamieson, Nigel B.; Søreide, Kjetil (Peer reviewed; Journal article, 2019)An increasing number of patients are being referred to pancreatic centres around the world due to often incidentally discovered cystic neoplasms of the pancreas. The evaluation and management of pancreatic cystic neoplasms ... -
Refined TNM-staging for pancreatic adenocarcinoma – Real progress or much ado about nothing?
Roalsø, Marcus Thomas Thor; Aunan, Jan Rune; Søreide, Kjetil (Journal article; Peer reviewed, 2020-02-20)In order to provide optimal cancer care and prognostication, it is necessary to stage the disease. The 8th edition of the TNM-staging for exocrine pancreatic ductal adenocarcinoma (PDAC) system has refined size-based ...