Blar i Department of Clinical Medicine på tittel
Viser treff 345-364 av 2060
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Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition
(Journal article; Peer reviewed, 2020-04-21)The etiology of Parkinson’s disease is largely unknown. Genome-wide transcriptomic studies in bulk brain tissue have identified several molecular signatures associated with the disease. While these studies have the potential ... -
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
(Journal article; Peer reviewed, 2021)Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical ... -
Comorbidity in multiple sclerosis patients from Nordland County, Norway - validated data from the Norwegian Patient Registry
(Journal article; Peer reviewed, 2021)Background: Knowledge of comorbid disorders is important to optimize therapy for multiple sclerosis (MS), but data are limited. The aim of this study was to assess comorbidity in persons with MS living in Nordland County ... -
Comparable Increases in Dural Sac Area After Three Different Posterior Decompression Techniques for Lumbar Spinal Stenosis: Radiological Results From a Randomized Controlled Trial in the NORDSTEN Study
(Journal article; Peer reviewed, 2020)Purpose: To investigate changes in dural sac area after three different posterior decompression techniques in patients undergoing surgery for lumbar spinal stenosis. Decompression of the nerve roots is the main surgical ... -
Comparative effectiveness of microdecompression alone vs decompression plus instrumented fusion in lumbar degenerative spondylolisthesis
(Journal article; Peer reviewed, 2020)Importance Conflicting evidence and large practice variation are present in the surgical treatment of degenerative spondylolisthesis. More than 90% of surgical procedures in the United States include instrumented fusion ... -
Comparative retention and effectiveness of migraine preventive treatments: A nationwide registry-based cohort study
(Journal article; Peer reviewed, 2023)Background and purpose Little is known about the comparative effects of migraine preventive drugs. We aimed to estimate treatment retention and effectiveness of migraine preventive drugs in a nationwide registry-based ... -
Comparative Risk of Major Congenital Malformations With Antiseizure Medication Combinations vs Valproate Monotherapy in Pregnancy
(Journal article; Peer reviewed, 2023)Background and Objectives Valproate should be avoided in pregnancy, but it is the most effective drug for generalized epilepsies. Alternative treatment may require combinations of other drugs. Our objectives were to ... -
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations
(Journal article; Peer reviewed, 2022)Objective: This study was undertaken to examine the comparative safety of antiseizure medication (ASM) monotherapy in pregnancy with respect to risk of major congenital malformations (MCMs), overall and by MCM subtype. ... -
Comparing radiopaque markers and 13C-labelled breath test in diabetic gastroparesis diagnostics
(Peer reviewed; Journal article, 2019)Purpose: Determining gastric emptying is mandatory in the diagnosis of diabetic gastroparesis. Several methods of investigation exist, but none has proven reliable, inexpensive and accessible. In this study, we aimed to ... -
Comparing screening outcomes for digital breast tomosynthesis and digital mammography by automated breast density in a randomized controlled trial: Results from the to-be trial
(Journal article; Peer reviewed, 2020)Background: Digital breast tomosynthesis (DBT) is considered superior to digital mammography (DM) for women with dense breasts. Purpose: To identify differences in screening outcomes, including rates of recall, ... -
Comparing the impact of upfront radiosurgery versus expectation in vestibular schwannoma (the V-REX study): protocol for a randomised, observer-blinded, 4-year, parallel-group, single-centre, superiority study
(Journal article; Peer reviewed, 2021)Introduction The optimal management of small-sized to medium-sized vestibular schwannoma (VS) is a matter of controversy. Clinical results of the prevailing treatment modalities (microsurgery, stereotactic radiosurgery ... -
Comparing the mitochondrial signatures in ESCs and iPSCs and their neural derivations
(Journal article; Peer reviewed, 2022)Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have distinct origins: ESCs are derived from pre-implanted embryos while iPSCs are reprogrammed somatic cells. Both have their own characteristics and ... -
Comparing withdrawal and non-withdrawal of life-sustaining treatment among patients who died from stroke
(Peer reviewed; Journal article, 2015)Background: In severe stroke, a decision to withdraw life-sustaining treatment is sometimes made in cooperation with the family. The aim of this study was to study the time from withdrawing life-sustaining treatment to ... -
A comparison between hyaluronic acid and other single ingredient eye drops for dry eye, a review
(Journal article; Peer reviewed, 2023)Dry eye disease (DED) is a highly prevalent and debilitating condition. Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan that has a long history as a safe and effective DED treatment. HA is frequently used ... -
Comparison between Ischemic Stroke Patients <50 Years and ≥50 Years Admitted to a Single Centre: The Bergen Stroke Study
(Peer reviewed; Journal article, 2011)Introduction: Young adults are likely to differ from old patients concerning cerebral infarction. Methods: We compared characteristics of patients aged under and above 50 years, admitted to the Department of Neurology with ... -
Comparison of 3 Different Minimally Invasive Surgical Techniques for Lumbar Spinal Stenosis: A Randomized Clinical Trial
(Journal article; Peer reviewed, 2022)Importance: Operations for lumbar spinal stenosis is the most often performed surgical procedure in the adult lumbar spine. This study reports the clinical outcome of the 3 most commonly used minimally invasive posterior ... -
Comparison of a digital iodine-specific dietary screener with 24-hour recall and urinary iodine concentration
(Journal article; Peer reviewed, 2023)Mild-to-moderate iodine deficiency remains a problem worldwide, including in Norway. Of particular, concern is fertile, pregnant and lactating women. The Norwegian Dairy Council developed a digital iodine-specific dietary ... -
Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels
(Peer reviewed; Journal article, 2014-01-21)Background: In colorectal cancer a distinct subgroup of tumours demonstrate the CpG island methylator phenotype (CIMP). However, a consensus of how to score CIMP is not reached, and variation in definition may influence ... -
Comparison of dietary intake measured by a web-based FFQ and repeated 24-hour dietary recalls: the Hordaland Health Study
(Journal article; Peer reviewed, 2022)All dietary assessment methods inevitably introduce measurement errors, which should ideally be considered during data analysis and interpretation. Methodological studies should be conducted to address how well a given ... -
A comparison of men and women undergoing septoplasty—the Swedish national septoplasty register
(Journal article; Peer reviewed, 2023)Objective: Men represent more than two-thirds of septoplasty patients in many studies, but differences between men and women in terms of patient selection or outcome are seldom reported. This study aims to investigate ...