Blar i Department of Clinical Medicine på tittel

Viser treff 550-569 av 2061

    • Early constipation predicts faster dementia onset in Parkinson's disease 

      Camacho, Marta; Macleod, Angus D.; Grødem, Jodi Maple; Evans, Jonathan R.; Breen, David P.; Cummins, G; Wijeyekoon, Ruwani; Greenland, Julia; Alves, Guido Werner; Tysnes, Ole-Bjørn; Lawson, Rachel A.; Barker, Roger A.; Williams-Gray, Caroline H. (Journal article; Peer reviewed, 2021)
      Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson’s ...

    • Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta‑analysis 

      Vermeulen, Bram D.; van der Leeden, Britt; Ali, Jawad T.; Gudbjartsson, Tomas; Hermansson, Michael; Low, Donald E.; Adler, Douglas G.; Botha, Abraham J.; D’Journo, Xavier B.; Eroglu, Atila; Ferri, Lorenzo E.; Gubler, Christoph; Haveman, Jan Willem; Kaman, Lileswar; Kozarek, Richard A.; Law, Simon; Loske, Gunnar; Lindenmann, Joerg; Park, Jung-Hoon; Richardson, J. David; Salminen, Paulina; Song, Ho-Yong; Søreide, Jon Arne; Spaander, Manon; Tarascio, Jeffrey N.; Tsai, Jon A.; Vanuytsel, Tim; Rosman, Camiel; Siersema, Peter D.; van der Bogt, Ruben D.; Birch, Madeleine; Dubose, Joseph J.; Fox, Sam; Jaklitsch, Michael T.; Kuppusamy, Madhan K.; Persson, Saga; Rice, Robert D.; Smolle, Josef; Smolle-Juettner, Freyja M.; Sudarshan, Monisha; Sutcliffe, Robert P.; Vidarsdottir, Halla; Viste, Asgaut (Journal article; Peer reviewed, 2020)
      Background Time of diagnosis (TOD) of benign esophageal perforation is regarded as an important risk factor for clinical outcome, although convincing evidence is lacking. The aim of this study is to assess whether time ...

    • Early Diagnosis of Pancreatic Cancer: Clinical Premonitions, Timely Precursor Detection and Increased Curative-Intent Surgery 

      Søreide, Kjetil; Ismail, Warsan; Roalsø, Marcus Thomas Thor; Ghotbi, Jacob; Zaharia, Claudia (Journal article; Peer reviewed, 2023)
      Background: The overall poor prognosis in pancreatic cancer is related to late clinical detection. Early diagnosis remains a considerable challenge in pancreatic cancer. Unfortunately, the onset of clinical symptoms in ...

    • Early Forms of α-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson’s Disease 

      Flønes, Irene Hana; Nyland, Harald Inge; Sandnes, Dagny Ann; Alves, Guido Werner; Tysnes, Ole-Bjørn; Tzoulis, Charalampos (Journal article; Peer reviewed, 2022)
      Idiopathic Parkinson’s disease (iPD) is characterized by degeneration of the dopaminergic substantia nigra pars compacta (SNc), typically in the presence of Lewy pathology (LP) and mitochondrial respiratory complex I (CI) ...

    • Early identification of treatment non-response in first-episode psychosis 

      Wold, Kristin Fjelnseth; Ottesen, Akiah; Flaaten, Camilla Bärthel; Johnsen, Erik; Lagerberg, Trine Vik; Romm, Kristin Lie; Simonsen, Carmen; Ueland, Torill; Widing, Line Hustad; Åsbø, Gina; Melle, Ingrid (Journal article; Peer reviewed, 2023)
      Background Approximately one-third of patients with psychotic disorders does not respond to standard antipsychotic treatments. Consensus criteria for treatment resistance (TR) may aid the identification of non-response ...

    • Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative 

      Hughes, Derralynn A.; Aguiar, Patricio; Deegan, Patrick B; Ezgu, Fatih; Frustaci, Andrea; Lidove, Olivier; Linhart, Aleš; Lubanda, Jean-Claude; Moon, James C; Nicholls, Kathleen; Niu, Dau-Ming; Nowak, Albina; Ramaswami, Uma; Reisin, Ricardo; Rozenfeld, Paula; Schiffmann, Raphael; Svarstad, Einar; Thomas, Mark; Torra, Roser; Vujkovac, Bojan; Warnock, David G.; West, Michael L; Johnson, Jack; Rolfe, Mark J; Feriozzi, Sandro (Journal article; Peer reviewed, 2020)
      Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ...

    • Early neurological worsening in acute ischaemic stroke patients 

      Nacu, Aliona; Bringeland, Gerd Haga; Khanevski, Andrej; Thomassen, Lars; Waje-Andreassen, Ulrike; Næss, Halvor (Peer reviewed; Journal article, 2016-01)
      Objectives: Neurological worsening in acute ischaemic stroke patients is common with significant morbidity and mortality. Aims: To determine the factors associated with early neurological worsening within the first 9 h ...

    • Early Parkinson’s Disease. Incidence, clinical features and quality of life in a population-based cohort study. 

      Müller, Bernd (Doctoral thesis, 2014-06-06)
      Background: The prevalence of Parkinson’s Disease (PD) in Norway is about 100/100 000 inhabitants. For planning of health care needs and for research purposes, incidence figures are considered the more valuable information, ...

    • Early screening outcomes among non-immigrants and immigrants targeted by BreastScreen Norway, 2010–2019 

      Thy, Jonas Evensen; Bhargava, Sameer; Larsen, Marthe; Akslen, Lars Andreas; Hofvind, Solveig Sand-Hanssen (Journal article; Peer reviewed, 2022)
      Aims: This study aimed to analyse results on early screening outcomes, including recall and cancer rates, and histopathological tumour characteristics among non-immigrants and immigrants invited to BreastScreen ...

    • Early screening outcomes before, during, and after a randomized controlled trial with digital breast tomosynthesis 

      Holen, åsne Sørlien; Bergan, Marie Burns; Lee, Christoph I.; Zackrisson, Sophia; Moshina, Nataliia; Aase, Hildegunn Siv; Haldorsen, Ingfrid S.; Hofvind, Solveig Sand-Hanssen (Journal article; Peer reviewed, 2023)
      Purpose To describe and compare early screening outcomes before, during and after a randomized controlled trial with digital breast tomosynthesis (DBT) including synthetic 2D mammography versus standard digital mammography ...

    • Early start of enzyme replacement therapy in pediatric male patients with classical Fabry disease is associated with attenuated disease progression 

      van der Veen, Sanne; Körver, Simon; Hirsch, A; Hollak, Carla E.M.; Wijburg, Frits A; Brands, M; Tøndel, Camilla; Van Kuilenburg, André B.P.; Langeveld, Miriam (Journal article; Peer reviewed, 2022)
      Background Enzyme replacement therapy (ERT) slows disease progression of Fabry disease (FD), especially when initiated before the onset of irreversible organ damage. However, with the clinically asymptomatic progression ...

    • Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients 

      Weibell, Melissa Anne E; Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Peer reviewed; Journal article, 2019-07-12)
      Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ...

    • Economic aspects of Parkinson’s disease 

      Vossius, Corinna (Doctoral thesis, 2009-11-13)
      Background: Next to Alzheimer’s disease, Parkinson’s disease (PD) is the second most neurodegenerative disease. As the population structure in the industrialized and industrializing countries is changing, an increasing ...

    • The economic impact of multiple sclerosis to the patients and their families in Norway 

      Svendsen, Bjørn; Grytten, Nina; Bø, Lars; Aarseth, Hallvard Gilje; Smedal, Tori; Myhr, Kjell-Morten (Peer reviewed; Journal article, 2018-12)
      Background: Multiple sclerosis (MS) imposes high economic costs on society, but the patients and their families have to bear some of these costs. Objective: We aimed to estimate the magnitude of these economic costs in ...

    • An economic model to evaluate cost-effectiveness of computer assisted knee replacement surgery in Norway 

      Gøthesen, Øystein Johannes; Slover, James; Havelin, Leif Ivar; Askildsen, Jan Erik; Malchau, Henrik; Furnes, Ove (Peer reviewed; Journal article, 2013-07-06)
      Background: The use of Computer Assisted Surgery (CAS) for knee replacements is intended to improve the alignment of knee prostheses in order to reduce the number of revision operations. Is the cost effectiveness of computer ...

    • Editorial: facts, figures and the future 

      Søreide, Kjetil (Peer reviewed; Journal article, 2015-01-09)

    • Educational supervisor's perceptions of their role in supporting residents' learning: a qualitative study 

      Birkeli, Cecilie Normann; Isaksson Rø, Karin Elisabet; Rustad, Lisbeth; Kvernenes, Monika (Journal article; Peer reviewed, 2023)
      Objectives: During the past decade, educational supervision (ES) has gained popularity as a key support mechanism in residents’ training. However, few studies have mapped physicians’ understanding of their roles as educational ...

    • Efect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial 

      Helland, Anita; Bratlie, Marianne; Hagen, Ingrid V.; Midttun, Øivind; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)
      Purpose Primarily, to investigate the effect of high intake of cod (lean fish) or salmon (fatty fish) on serum concentration of total neopterin, a marker of cellular immune activation that is associated with cardiovascular ...

    • The efectiveness of exercise therapy and education plus cognitive behavioral therapy, alone or in combination with total knee arthroplasty in patients with knee osteoarthritis – study protocol for the MultiKnee trial 

      Lindberg, Maren Falch; Aamodt, Arild; Badawy, Mona; Bergvad, Ingvild Buset; Borchgrevink, Petter Chr.; Furnes, Ove Nord; Gay, Caryl; Heir, Stig; Holm, Inger; Indrekvam, Kari; Kise, Nina Jullum; Lau, Bjørn; Magnussen, Jon; Nerhus, Tor Kjetil; Rognsvåg, Turid; Rudsengen, Daniil; Rustøen, Tone; Skou, Søren Thorgaard; Stubberud, Jan Egil; Småstuen, Milada Cvancarova; Lerdal, Anners (Journal article; Peer reviewed, 2021)
      Background One in five patients report chronic pain following total knee arthroplasty (TKA) and are considered non-improvers. Psychological interventions such as cognitive behavioral therapy (CBT), combined with exercise ...

    • Effect of a cod protein hydrolysate on postprandial glucose metabolism in healthy subjects: A double-blind cross-over trial 

      Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Lied, Einar; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (Peer reviewed; Journal article, 2018)
      The increased prevalence of lifestyle diseases, such as the metabolic syndrome and type 2 diabetes mellitus (T2DM), calls for more knowledge on dietary treatments targeting the specific metabolic pathways involved in these ...