Browsing Bergen Open Research Archive by Title
Now showing items 27088-27107 of 34347
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Role of Adipocyte SLC7A10 and Amino Acid Metabolism in Obesity and Insulin Resistance
(Doctoral thesis, 2020-12-18)Obesity is a rising global concern, associated with increased risk of developing metabolic syndrome, insulin resistance and type 2 diabetes. Chronic availability of excess nutrients may promote adipocyte dysfunction, ... -
The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
(Doctoral thesis, 2016-05-09)Aging is the critical risk factor for many forms of cancer. We used the mammary gland as a model system to study the impact of age on human epithelia in which age is the greatest risk factor for cancer. Dysfunctional ... -
The role of air–sea coupling on November–April intraseasonal rainfall variability over the South Pacific
(Journal article; Peer reviewed, 2022)We investigate the impact of resolving air-sea interaction on the simulation of the intraseasonal rainfall variability over the South Pacific using the ECHAM5 atmospheric general circulation model coupled with the ... -
The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
(Peer reviewed; Journal article, 2018-07-13)Background: Anti-citrullinated protein antibody (ACPA) reactivities precede clinical onset of rheumatoid arthritis (RA), and it has been suggested that ACPA reactivities towards distinct target proteins may be associated ... -
The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro
(Peer reviewed; Journal article, 2013-11-14)Background: Arginine is a conditionally essential amino acid important in growing individuals and under nonhomeostatic conditions/disease. Many pathogens interfere with arginine-utilization in host cells, especially nitric ... -
The Role of Atlantic Heat Transport in Future Arctic Winter Sea Ice Loss
(Peer reviewed; Journal article, 2019-05-14)During recent decades Arctic sea ice variability and retreat during winter have largely been a result of variable ocean heat transport (OHT). Here we use the Community Earth System Model (CESM) large ensemble simulation ... -
Role of atmosphere-ocean interactions in supermodeling the tropical Pacific climate
(Peer reviewed; Journal article, 2017-12-29)The supermodel strategy interactively combines several models to outperform the individual models comprising it. A key advantage of the approach is that nonlinear improvements can be achieved, in contrast to the linear ... -
Role of Atmosphere-ocean-ice Interaction in the Linkage between December Bering Sea Ice and Subsequent February Surface Air Temperature Over North America
(Journal article; Peer reviewed, 2023)This study revealed that the interannual variations of December Bering Sea ice and subsequent February surface air temperature (SAT) over North America are significantly correlated during 2000/01-2020/21, which is not the ... -
The role of authigenic sulfides in immobilization of potentially toxic metals in the Bagno Bory wetland, southern Poland
(Peer reviewed; Journal article, 2015-10)The supply of Cd, Cu, Fe, Pb, Zn, and Tl into a wetland in the industrial area of Upper Silesia, southern Poland via atmospheric precipitation and dust deposition has been counterbalanced by the biogenic metal sulfide ... -
The role of autoantibodies in cell mediated autoimmune Addison`s disease
(Master thesis, 2012-05-31)Background: Addison`s disease (primary adrenal insufficiency) is a prototypic organ-specific autoimmune disease affecting the adrenal cortex. Autoimmune Addison`s disease (AAD) is often characterized by autoantibodies ... -
The Role of Axl in Cancer and Stem Cell Plasticity: in vivo Lineage Tracing and Imaging Mass Cytometry Analysis
(Master thesis, 2019-11-14) -
The role of Axl in melanoma metastasis
(Master thesis, 2015-05-31)Melanoma is a highly invasive and metastatic cancer, thus understanding the mechanism of melanoma metastasis is a major issue. In our study, the objective is to elucidate the role of the receptor tyrosine kinase Axl in ... -
Role of Caveolin-1 in Hypoxia and Proneural to Mesenchymal Transition of Glioblastoma
(Master thesis, 2018-06-29)Glioblastomas (GBM), a grade IV astrocytoma, is the most common and aggressive primary brain tumors in adults, associated with short survival and uniformly fatal outcome irrespective of treatment. GBM is highly heterogeneous ... -
The Role of Civic Engagement for Men’s Health and Well Being in Norway - A Contribution to Public Health
(Peer reviewed; Journal article, 2014-06-18)Objectives: Using the example of older men volunteering on teams that restore historic ships, this article examines the effects of volunteering on the well-being of older adults. We consider particularly how volunteering ... -
The role of community conversations in facilitating local HIV competence: case study from rural Zimbabwe
(Peer reviewed; Journal article, 2013-04-17)Background: This paper examines the potential for community conversations to strengthen positive responses to HIV in resource-poor environments. Community conversations are an intervention method through which local people ... -
The role of culture and evolution for human cognition
(Peer reviewed; Journal article, 2019-08-08)Since the emergence of our species at least, natural selection based on genetic variation has been replaced by culture as the major driving force in human evolution. It has made us what we are today, by ratcheting up ... -
The Role of Diet in Irritable Bowel Syndrome with special reference to Gut Neuroendocrine System
(Doctoral thesis, 2015-08-28)Background: The majority of the patients with irritable bowel syndrome (IBS) believe that diet triggers their symptoms, which affect the quality of their lives. The pathophysiology of IBS is not exactly known, however, the ... -
The role of diet in the pathophysiology and management of irritable bowel syndrome
(Journal article; Peer reviewed, 2021)Irritable bowel syndrome (IBS) is a chronic gastrointestinal (GI) disorder that reportedly affects 5% to 20% of the world population. The etiology of IBS is not completely understood, but diet appears to play an important ... -
Role of dietary carbohydrate quality and quantity in visceral obesity reduction : Results from a randomized controlled trial (CARBFUNC)
(Doctoral thesis, 2022-03-25)Background: Increased visceral adipose tissue (VAT) volume is associated with common lifestyle diseases and poses an increasing health challenge worldwide. There is a great need for effective approaches that result in ... -
The role of dietary fat and carbohydrates in development of adipose tissue inflammation
(Master thesis, 2009-06-02)Obesity is considered as a chronic low-grade inflammatory condition, which can be characterized by increased levels of the proinflammatory cytokines such as TNF-α and IL-6, and macrophage infiltration in adipose tissue. ...