Previously, somatic hypermutation (SHM) was considered to be exclusively associated with affinity maturation of antibodies, although it also occurred in T cells under certain conditions. More recently, it has been shown ...

Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ...

Bakgrunn: Vi blir stadig eldre og med økende alder følger også økt morbiditet og dermed også medisinbruk. Mange eldre bor i omsorgsboliger og får tildelt medisiner av helsepersonell. Ofte kan det av ulike grunner være behov ...

This book highlights current debates about concepts, methods, and policies related to poverty in Latin America. It focuses on child and adolescent well-being and the issue of inclusive societies. Its goal is to promote new ...

Polyadenylation at the 3′-end is a major regulator of messenger RNA and its length is known to affect nuclear export, stability, and translation, among others. Only recently have strategies emerged that allow for genome-wide ...

This thesis concerns community events, especially those of festivals and parades, in Post-Katrina New Orleans. Based on my fieldwork of 2012, I have explored how participants in community events use these happenings as a ...

The paper presents a theoretical framework for studying reforms and organizational change; 1) change as the product of reformers’ intentions, 2) change in institutionalized norms and habits and 3) change as a consequence ...

I denne oppgaven har jeg søkt å analysere hva som kjennetegner hytteboktekster. Jeg ønsket å finne ut hvilke særegne karaktertrekk hytteboktekstene har, og hvordan de har utviklet seg over tid. I arbeidet med problemstillingen ...

Takrolimus er del av standard immunsuppresjon og vedlikeholdsdoseringsregimet etter levertransplantasjon. Det har et smalt terapeutisk vindu, og monitorers derfor etter bunnkonsentrasjonsmålinger. Intra- og interindividuelle ...