Blar i Bergen Open Research Archive på forfatter "Løberg, Else-Marie"
-
Akathisia and atypical antipsychotics. Relation to suicidality, agitation and depression in a clinical trial
Bjarke, Jill Kristin; Gjerde, Helga Nødland; Jørgensen, Hugo A; Kroken, Rune Andreas; Løberg, Else-Marie; Johnsen, Erik (Journal article; Peer reviewed, 2022)Objective: Akathisia is among the most unpleasant side effects related to antipsychotic drug (AP) use, and possible associations between akathisia and agitation, depression and suicidal behaviour, respectively, have been ... -
Amphetamine-induced psychosis - a separate diagnostic entity or primary psychosis triggered in the vulnerable?
Bramness, Jørgen G.; Gundersen, Øystein H.; Guterstam, Joar; Rognli, Eline B.; Konstenius, Maija; Løberg, Else-Marie; Medhus, Sigrid; Tanum, Lars; Franck, Johan (Peer reviewed; Journal article, 2012-12-05)Use of amphetamine and methamphetamine is widespread in the general population and common among patients with psychiatric disorders. Amphetamines may induce symptoms of psychosis very similar to those of acute schizophrenia ... -
Anti-depressive effectiveness of olanzapine, quetiapine, risperidone and ziprasidone: a pragmatic, randomized trial
Kjelby, Eirik; Jørgensen, Hugo A.; Kroken, Rune A.; Løberg, Else-Marie; Johnsen, Erik (Peer reviewed; Journal article, 2011-08-31)Background: Efficacy studies indicate anti-depressive effects of at least some second generation antipsychotics (SGAs). The Bergen Psychosis Project (BPP) is a 24-month, pragmatic, industry-independent, randomized, head-tohead ... -
Antidepressive Effectiveness of Amisulpride, Aripiprazole, and Olanzapine in Patients with Schizophrenia Spectrum Disorders: A Secondary Outcome Analysis of a Pragmatic, Randomized Trial (BeSt InTro)
Kjelby, Eirik; Gjestad, Rolf; Fathian, Farivar; Sinkeviciute, Igne; Alisauskiene, Renata; Anda, Liss; Løberg, Else-Marie; Reitan, Solveig Klæbo; Joa, Inge; Larsen, Tor Kjetil; Rettenbacher, Maria; Berle, Jan Øystein; Fasmer, Ole Bernt; Kroken, Rune Andreas; Johnsen, Erik (Journal article; Peer reviewed, 2023)Background Depressive symptoms are frequent in schizophrenia and associated with a poorer outcome. Currently, the optimal treatment for depressive symptoms in schizophrenia remains undetermined. Amisulpride, aripiprazole, ... -
Association between C-reactive protein levels and antipsychotic treatment during 12 months follow-up period after acute psychosis
Fathian, Farivar; Gjestad, Rolf; Kroken, Rune Andreas; Løberg, Else-Marie; Reitan, Solveig Merete Klæbo; Fleichhacker, W. Wolfgang; Rettenbacher, Maria; Larsen, Tor Ketil; Joa, Inge; Stabell, Lena Antonsen; Kjelby, Eirik; Sinkevicute, Igne; Alisauskiene, Renata; Steen, Vidar Martin; Johnsen, Erik (Journal article; Peer reviewed, 2022)Background A potential role of inflammatory pathways in the pathology of schizophrenia has been suggested for at least a subgroup of patients. Elevated levels of the inflammatory marker C-reactive protein (CRP) have been ... -
The association between cytokines and psychomotor speed in a spectrum of psychotic disorders: A longitudinal study
Larsen, Jeanette Brun; Reitan, Solveig Merete Klæbo; Løberg, Else-Marie; Rettenbacher, Maria; Bruserud, Øystein; Larsen, Tor Ketil; Anda, Liss Gøril; Bartz-Johannessen, Christoffer; Johnsen, Erik; Kroken, Rune Andreas (Journal article, 2021)Background In schizophrenia, impaired psychomotor speed is a common symptom predicting worse functional outcome. Inflammation causes changes in white matter integrity, which may lead to reduced psychomotor speed. Therefore, ... -
The association between lithium use and neurocognitive performance in patients with bipolar disorder
Burdick, Katherine E.; Millett, Caitlin E.; Russo, Manuela; Alda, Martin; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; DeModena, Anna; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Glazer, Kara; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Løberg, Else-Marie; Lohoff, Falk W.; Maihofer, Adam X.; McCarthy, Michael J.; McInnis, Melvin; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Oedegaard, Ketil J.; Ortiz, Abigail; Ritchey, Megan; Ryan, Kelly; Schinagle, Martha; Schwebel, Candice; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma; Tarwater, Bruce; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2020)Lithium remains the gold standard for the treatment of bipolar disorder (BD); however, its use has declined over the years mainly due to the side effects and the subjective experience of cognitive numbness reported by ... -
Attention-deficit/hyperactivity disorder (ADHD) symptoms and their relation to diagnosed ADHD, sociodemographic characteristics, and substance use among patients receiving opioid agonist therapy: a Norwegian cohort study
Vold, Jørn Henrik; Halmøy, Anne; Chalabianloo, Fatemeh; Pierron, Marianne Cook; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2023)Background Attention-deficit/hyperactivity disorder (ADHD) symptoms may challenge sufficient treatment of substance use and mental disorders. The literature on the extent of such symptoms among patients receiving opioid ... -
Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study
Tønnesen, Siren; Kaufmann, Tobias; de Lange, Ann-Marie Glasø; Richard, Geneviève; Nhat Trung, Doan; Alnæs, Dag; van der Meer, Dennis; Rokicki, Jaroslav; Moberget, Torgeir; Maximov, Ivan; Agartz, Ingrid; Aminoff, Sofie Ragnhild; Beck, Dani; Barch, Deanna M.; Beresniewicz, Justyna; Cervenka, Simon; Fatouros-Bergman, Helena; Craven, Alexander R.; Flyckt, Lena; Gurholt, Tiril Pedersen; Haukvik, Unn Kristin H.; Hugdahl, Kenneth; Johnsen, Erik; Jönsson, Erik Gunnar; Schizophrenia Project (KaSP), Karolinska; Kolskår, Knut-Kristian; Kroken, Rune Andreas; Lagerberg, Trine Vik; Løberg, Else-Marie; Nordvik, Jan Egil; Sanders, Anne-Marthe; Ulrichsen, Kristine Moe; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Journal article; Peer reviewed, 2020)Background Schizophrenia (SZ) and bipolar disorder (BD) share substantial neurodevelopmental components affecting brain maturation and architecture. This necessitates a dynamic lifespan perspective in which brain aberrations ... -
The cannabis pathway to non-affective psychosis may reflect less neurobiological vulnerability
Løberg, Else-Marie; Helle, Siri; Nygård, Merethe; Berle, Jan Øystein; Kroken, Rune; Johnsen, Erik (Peer reviewed; Journal article, 2014-11-18)There is a high prevalence of cannabis use reported in non-affective psychosis. Early prospective longitudinal studies conclude that cannabis use is a risk factor for psychosis, and neurochemical studies on cannabis have ... -
Changes in substance use during outpatient treatment for substance use disorders: a prospective Norwegian cohort study from 2016 to 2020
Vold, Jørn Henrik; Chalabianloo, Fatemeh; Aas, Christer Frode; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2021)Background Continuous use of amphetamines, alcohol, benzodiazepines, cannabis, cocaine, or opioids contributes to health impairments, increased morbidity, and overdose deaths among patients with substance use disorders ... -
Clinical insight among persons with schizophrenia spectrum disorders treated with amisulpride, aripiprazole or olanzapine: a semi-randomised trial
Stabell, Lena Antonsen; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Blindheim, Anne Alnes; Joa, Inge; Reitan, Solveig Klæbo; Rettenbacher, M.; Munk-Jørgensen, P.; Gjestad, Rolf (Journal article; Peer reviewed, 2023)Background Antipsychotic treatment may improve clinical insight. However, previous studies have reported inconclusive findings on whether antipsychotics improve insight over and above the reduction in symptoms of ... -
Cognitive change and antipsychotic medications: Results from a pragmatic rater-blind RCT
Anda, Liss; Johnsen, Erik; Kroken, Rune A.; Joa, Inge; Rettenbacher, Maria; Løberg, Else-Marie (Journal article; Peer reviewed, 2021)Cognitive impairment is a core aspect of psychotic disorders and difficult to treat. Atypical antipsychotics (AAs) might have differential effects on cognitive impairment, but rigid study designs and selective sampling ... -
Cognitive changes in patients with acute phase psychosis - Effects of illicit drug use
Helle, Siri; Gjestad, Rolf; Johnsen, Erik; Kroken, Rune; Jørgensen, Hugo A.; Løberg, Else-Marie (Peer reviewed; Journal article, 2014-12)Illicit drug use may influence cognition in non-affective psychosis. Previous studies have shown better cognition in psychosis with illicit drug use as compared to psychosis only. Possibly, illicit drug using patients have ... -
Cognitive profile in ultra high risk for psychosis and schizophrenia: A comparison using coordinated norms
Anda-Ågotnes, Liss Gøril; Brønnick, Kolbjørn Kallesten; Johannessen, Jan Olav; Joa, Inge; Kroken, Rune Andreas; Johnsen, Erik; Rettenbacher, Maria; Fathian, Farivar; Løberg, Else-Marie (Peer reviewed; Journal article, 2019-10-01)Background: Cognitive impairment is not only a core aspect of schizophrenia but also commonly observed in help-seeking youth at ultra high risk for psychosis (UHR), with potential implications for prognosis and individualized ... -
A critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation
Kroken, Rune; Løberg, Else-Marie; Drønen, Tore; Grüner, Renate; Hugdahl, Kenneth; Kompus, Kristiina; Skrede, Silje; Johnsen, Erik (Peer reviewed; Journal article, 2014-02-04)Antipsychotic drugs have thus far focused on dopaminergic antagonism at the D2 receptors, as counteracting the hyperdopaminergia in nigrostriatal and mesolimbic projections has been considered mandatory for the antipsychotic ... -
Differential Effectiveness of Atypical Antipsychotics on Hallucinations: A Pragmatic Randomized Controlled Trial
Sinkeviciute, Igne; Hugdahl, Kenneth Jan; Bartz-Johannessen, Christoffer; Kroken, Rune Andreas; Løberg, Else-Marie; Kjelby, Eirik; Rettenbacher, maria; Joa, Inge; Reitan, Solveig Merete Klæbo; Alisauskiene, Renata; Fathian, Farivar; Johnsen, Erik (Journal article; Peer reviewed, 2021-07)Background Most studies investigating antipsychotic effectiveness report either total psychopathology or symptom cluster findings. Studies focusing on a separate symptom, such as hallucinations, a hallmark symptom in ... -
Does changing from a first generation antipsychotic (perphenazin) to a second generation antipsychotic (risperidone) alter brain activation and motor activity? A case report
Berle, Jan Øystein; Løberg, Else-Marie; Fasmer, Ole Bernt (Peer reviewed; Journal article, 2013-05-06)Background: In patients with schizophrenia, altered brain activation and motor activity levels are central features, reflecting cognitive impairments and negative symptoms, respectively. Newer studies using nonlinear methods ... -
Does childhood trauma influence cognitive functioning in schizophrenia? The association of childhood trauma and cognition in schizophrenia spectrum disorders.
Mørkved, Nina; Johnsen, Erik; Kroken, Rune Andreas; Gjestad, Rolf; Winje, Dagfinn; Thimm, J.; Fathian, Farivar; Rettenbacher, Maria; Anda-Ågotnes, Liss Gøril; Løberg, Else-Marie (Journal article; Peer reviewed, 2020)Childhood trauma (CT) is a risk factor for schizophrenia spectrum disorders (SSDs), and cognitive impairment is a core feature and a vulnerability marker of SSDs. Studies of the relationship between CT and cognitive ... -
Does drug use affect the efficacy of amisulpride, aripiprazole and olanzapine in patients with schizophrenia spectrum disorders? Results from a pragmatic, randomised study
Alisauskiene, Renata; Johnsen, Erik; Gjestad, Rolf; Kroken, Rune Andreas; Kjelby, Eirik; Sinkeviciute, Igne; Fathian, Farivar; Joa, Inge; Reitan, Solveig Klæbo; Rettenbacher, Maria; Løberg, Else-Marie (Journal article; Peer reviewed, 2023)Objectives Drug use is prevalent in patients with schizophrenia spectrum disorders (SSD) but there is limited knowledge about the influence of drug use on the effectiveness of antipsychotic medication. This secondary ...