Blar i Bergen Open Research Archive på tittel
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Immunocytochemical detection of Mycobacterium Tuberculosis complex specific antigen, MPT64, improves diagnosis of tuberculous lymphadenitis and tuberculous pleuritis
(Peer reviewed; Journal article, 2014-11-25)Background: A rapid, sensitive and accurate laboratory diagnosis is of prime importance in suspected extrapulmonary tuberculosis (EPTB) cases. However, traditional techniques for the detection of acid-fast bacilli have ... -
The immunogenicity of intranasal adjuvanted pandemic avian influenza vaccine in murine model
(Master thesis, 2009-07-02)Influenza vaccination remains the primary method for the prevention of influenza and the severe complications related to the disease. Development of an intranasal vaccination strategy will not only prevent the disease but ... -
Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar
(Peer reviewed; Journal article, 2015-02)There are three major immunoglobulin (Ig) isotypes in salmonid fish: IgM, IgD and IgT, defined by the heavy chains , and , respectively. As a result of whole genome duplication in the ancestor of the salmonid fish family, ... -
Immunoglobulin-storing histiocytosis: A case based systemic review
(Journal article; Peer reviewed, 2021)Crystal-storing histiocytosis (CSH) is a rare event in disorders associated with monoclonal gammopathy and is mostly associated with the accumulation of immunoglobulins (Igs) in the cytoplasm of histiocytes. In this article, ... -
Immunohaematological reference values in human immunodeficiency virus-negative adolescent and adults in rural northern Tanzania
(Peer reviewed; Journal article, 2009-01-13)Background: The amount of CD4 T cells is used for monitoring HIV progression and improvement, and to make decisions to start antiretroviral therapy and prophylactic drugs for opportunistic infections. The aim of this study ... -
Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer
(Journal article; Peer reviewed, 2021)Objective: Pre-operative immunohistochemical (IHC) biomarkers are not incorporated in endometrial cancer (EC) risk classification. We aim to investigate the added prognostic relevance of IHC biomarkers to the ESMO-ESGO-ESTRO ... -
Immunohistochemical detection of p53 in non-malignant and malignant oral lesions associated with snuff dipping in the Sudan and Sweden
(Journal article, 1996)Immunohistochemistry was used to examine the expression of p53 in pre-malignant oral lesions and oral squamous-cell carcinomas (SCCs) from Swedish and Sudanese snuff-dippers, as well as in pre-malignant oral lesions and ... -
Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64
(Peer reviewed; Journal article, 2007-09-25)Background: The aim of this study was to evaluate the diagnostic potential of immunohistochemistry using an antibody to the secreted mycobacterial antigen MPT64, in abdominal and lymph node tuberculosis. Methods: We used ... -
Immunological aspects of acute myelogenous leukemia
(Doctoral thesis, 2007-02-23)Acute myelogenous leukemia (AML) is an aggressive malignancy characterized by accumulation of immature myeloid cells in the bone marrow. The overall disease-free survival is less than 50% even for the younger patients who ... -
The immunological dilemma: Cellular innate and adaptive immune response versus human acute myeloid leukemia
(Peer reviewed; Journal article, 2007)It is generally accepted that acute myelogenous leukemia (AML) patients are immunocompromized. On the other hand, antileukemic immune reactivity is important for the improved survival of AML patients treated with allogeneic ... -
Immunological heterogeneity of healthy peripheral blood stem cell donors - Effects of granulocyte colony-stimulating factor on inflammatory responses
(Peer reviewed; Journal article, 2018-09-22)Interleukin-6 (IL-6) contributes to the development of immune-mediated complications after allogeneic stem cell transplantation. However, systemic IL-6 levels also increase during granulocyte colony-stimulating factor ... -
Immunological mechanisms of tumour progression. The rationale for natural killer cell based immunotherapy for glioblastoma
(Doctoral thesis, 2013-10-04)Glioblastoma (GBM) is the most frequent and malignant brain tumour, where the patients’ median survival after diagnosis is only 14.6 months. Therefore, concerted research is required to develop novel treatments that will ... -
Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line
(Journal article; Peer reviewed, 2019)Changes in the immune system induced by tyrosine kinase inhibitors (TKI) have been shown to positively correlate with therapy responses in chronic myeloid leukemia (CML). However, only a few longitudinal studies exist and ... -
Immunologiske responsar i huda hos sjøaure (Salmo trutta) ved infeksjon av lakselus (Lepeophtheirus salmonis) i preadulte stadiet
(Master thesis, 2022-06-01)Sjøaure er den anadrome delen av bestanden til brunaure (Salmo trutta). Arten gyter i elvar og bekkar før den smoltifiserer og vandrar ut i kystvatn for å finne større tilgang til føde og dermed vokse seg større. I kystvatn ... -
The immunology of the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome; what can the tonsils reveal. A literature review.
(Peer reviewed; Journal article, 2020)Objectives: Tonsillectomy (TE) or adenotonsillectomy (ATE) may have a beneficial effect on the clinical course in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. ... -
Immunomodulation induced by stem cell mobilization and harvesting in healthy donors: Increased systemic osteopontin levels after treatment with granulocyte colony-stimulating factor
(Peer reviewed; Journal article, 2016-07-19)Peripheral blood stem cells from healthy donors mobilized by granulocyte colony-stimulating factor (G-CSF) and harvested by leukapheresis are commonly used for allogeneic stem cell transplantation. The frequency of severe ... -
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells
(Peer reviewed; Journal article, 2018-01-29)Serotonin is a monoamine neurotransmitter that signals through a wide array of receptors (5-HT1–7) many of which are also involved in immune processes. Dendritic cells (DCs) are crucial players in immune defense by bridging ... -
Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes
(Journal article; Peer reviewed, 2020)Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting stromal cells. ... -
Immunophenotyping in post-giardiasis functional gastrointestinal disease and chronic fatigue syndrome
(Peer reviewed; Journal article, 2012-10-14)Background: A Giardia outbreak was associated with development of post-infectious functional gastrointestinal disorders (PI-FGID) and chronic fatigue syndrome (PI-CFS). Markers of immune dysfunction have given conflicting ... -
Immunoregulatory networks in healthy adult allogeneic stem cell donors : Studies of peripheral hematopoietic stem cell donors and their recipients
(Doctoral thesis, 2020-10-28)Final outcome after allogeneic peripheral blood stem cell transplantation (PBSCT) is influenced by the high degrees of variation in disease and comorbidities among recipients, as well as the pre-and post-transplant handling ...