Blar i Bergen Open Research Archive på forfatter "Mustafa, Kamal Babikeir Eln"
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Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering
Shanbhag, Siddharth; Mohamed Ahmed, Samih; Lunde, Turid Helen Felli; Suliman, Salwa; Bolstad, Anne Isine; Hervig, Tor; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the expansion of mesenchymal stromal cells (MSCs) for bone tissue engineering (BTE) applications. Due to a growing demand, the ... -
Influence of type 2 diabetes on local production of inflammatory molecules in adults with and without chronic periodontitis: A cross-sectional study
Mohamed, Hasaan Gassim; Idris, Shaza Bushra; Ahmed, Mutaz F.; Åstrøm, Anne Nordrehaug; Mustafa, Kamal Babikeir Eln; Ibrahim, Salah Osman; Mustafa, Manal (Peer reviewed; Journal article, 2015-07-27)Background Pathological changes in periodontal tissues are mediated by the interaction between microorganisms and the host immune-inflammatory response. Hyperglycemia may interfere with this process. The aim of this study ... -
Influence of type 2 diabetes on prevalence of key periodontal pathogens, salivary matrix metalloproteinases and bone remodeling markers in adults with and without chronic periodontitis
Mohamed, Hasaan Gassim; Idris, Shaza Bushra Mohamed; Mustafa Sharafeldin, Manal Ibrahim; Ahmed, Mutaz Faisal; Åstrøm, Anne Nordrehaug; Mustafa, Kamal Babikeir Eln; Ibrahim, Salah Osman (Peer reviewed; Journal article, 2016)This study compared the influence of type 2 diabetes on the occurrence of six periodontal pathogens in plaque samples of patients with and without chronic periodontitis. Levels of salivary MMP-8, MMP-9, RANKL, and OPG were ... -
Leukocyte transmigration into tissue-engineered constructs is influenced by endothelial cells through Toll-like receptor signaling
Bartaula-Brevik, Sushma; Pedersen, Torbjorn Østvik; Blois, Anna L; Papadakou, Panagiota; Finne-Wistrand, Anna; Xue, Ying; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2014-12-20)Introduction Inflammation plays a crucial role in tissue regeneration, wound healing, and the success of tissue-engineered constructs. The aim of this study was to investigate the influence of human umbilical vein endothelial ... -
Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
Pedersen, Torbjørn Østvik; Blois, Anna L; Xue, Ying; Xing, Zhe; Sun, Yang; Finne-Wistrand, Anna; Lorens, James B.; Fristad, Inge; Leknes, Knut N.; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2014-02-17)Introduction: Rapid establishment of functional blood vessels is a prerequisite for successful tissue engineering. During vascular development, endothelial cells (ECs) and perivascular cells assemble into a complex regulating ... -
Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes
Suliman, Salwa; Mustafa, Kamal Babikeir Eln; Krueger, Anke; Steinmüller-Nethl, Doris; Finne-Wistrand, Anna; Osdal, Tereza; Osman, Amani Hamza Ali; Sun, Yang; Parajuli, Himalaya; Waag, Thilo; Nickel, Joachim; Johannessen, Anne Christine; McCormack, Emmet; Costea, Daniela Elena (Peer reviewed; Journal article, 2016-07)This study aimed to evaluate the tumorigenic potential of functionalising poly(LLA-co-CL) scaffolds. The copolymer scaffolds were functionalised with nanodiamonds (nDP) or with nDP and physisorbed BMP-2 (nDP-PHY) to enhance ... -
Neuronal plasticity of trigeminal ganglia in mice following nerve injury
Lynds, Randi; Lyu, Chuang; Lyu, Gong-Wei; Shi, Xie-Qi; Rosén, Annika; Mustafa, Kamal Babikeir Eln; Shi, Tie-Jun (Peer reviewed; Journal article, 2017-02-09)Background: Nerve injury may induce neuropathic pain. In studying the mechanisms of orofacial neuropathic pain, attention has been paid to the plastic changes that occur in the trigeminal ganglia (TGs) and nucleus in ... -
Patient experience following iliac crest alveolar bone gradfting av implant replacement
Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Gjengedal, Harald; Shanbhag, Siddharth; Neppelberg, Evelyn (Journal article; Peer reviewed, 2020-02-05)Background The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment ... -
Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo
Suliman, Salwa; Xing, Zhe; Wu, X; Xue, Ying; Pedersen, Torbjørn Østvik; Sun, Y; Døskeland, Anne Marie Simonne; Nickel, Joachim; Waag, Thilo; Lygre, Henning; Finne Wistrand, Anna; Steinmüller-Nethl, Doris; Krueger, Anke; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2015-01-10)A low dose of 1 μg rhBMP-2 was immobilised by four different functionalising techniques on recently developed poly(l-lactide)-co-(ε-caprolactone) [(poly(LLA-co-CL)] scaffolds. It was either (i) physisorbed on unmodified ... -
Site-specific treatment outcome in smokers following 12 months of supportive periodontal therapy
Bunæs, Dagmar Fosså; Lie, Stein Atle; Åstrøm, Anne Nordrehaug; Mustafa, Kamal Babikeir Eln; Leknes, Knut N. (Peer reviewed; Journal article, 2016-12)Aim: To evaluate the effect of cigarette smoking on periodontal health at patient, tooth, and site levels following supportive therapy. Materials and Methods: Eighty chronic periodontitis patients, 40 smokers and 40 ... -
Surface activation with oxygen plasma promotes osteogenesis with enhanced extracellular matrix formation in three- dimensional microporous scaffolds
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Weigel, Tobias; Schmitz, Tobias; Hansmann, Jan; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2021)Various types of synthetic polyesters have been developed as biomaterials for tissue engineering. These materials commonly possess biodegradability, biocompatibility, and formability, which are preferable properties for ... -
Translation of a standardized manufacturing protocol for mesenchymal stromal cells: A systematic comparison of validation and manufacturing data
Rojewski, Markus Thomas; Lofti, Ramin; Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Veronesi, Elena; Ahmed, Aymen B; Wiesneth, Markus; Körper, Sixten; Sensebé, Luc; Layrolle, Pierre; Hellem, Sølve; Schrezenmeier, Hubert (Journal article; Peer reviewed, 2019)Background Many data are available on expansion protocols for mesenchymal stromal cells (MSCs) for both experimental settings and manufacturing for clinical trials. However, there is a lack of information on translation ... -
Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering
Shanbhag, Siddharth; Suliman, Salwa; Bolstad, Anne Isine; Stavropoulos, Andreas; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)Gingiva has been identified as a minimally invasive source of multipotent progenitor cells (GPCs) for use in bone tissue engineering (BTE). To facilitate clinical translation, it is important to characterize GPCs in xeno-free ...