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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
(Peer reviewed; Journal article, 2019-04-23)Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in ... -
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1
(Peer reviewed; Journal article, 2015-12-01)High-risk mutations in several genes predispose to both colorectal cancer (CRC) and endometrial cancer (EC). We therefore hypothesised that some lower-risk genetic variants might also predispose to both CRC and EC. Using ... -
A meta-analysis of income and democracy. Why we still have not reached consensus after 60 years of research
(Master thesis, 2015-06-02)The purpose of this study is to examine the relationship between per capita income and democracy. Namely, do increases in income per capita affect a regime's level of democracy? The scholarly tradition has investigated ... -
Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci
(Journal article; Peer reviewed, 2020-10-01)Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants ... -
A Meta-Analysis on the Link Between Young People's Social Environment, Socioeconomic Status, and Political Violence Outcomes
(Journal article; Peer reviewed, 2023)Young people are particularly likely to engage in political violence, hold positive attitudes towards political violence, and show willingness to engage in political violence. The social environment in which young people ... -
A meta-analysis on the nutritional value of insects in aquafeeds
(Journal article; Peer reviewed, 2021)A major challenge for development of sustainable aquafeeds is its dependence on fish meal and fish oil. Similarly, it is unwanted to include more plant ingredients which adds more pressure on resources like arable land, ... -
Meta-intelligence: understanding, control, and interactivity between creative, analytical, practical, and wisdom-based approaches in problem solving
(Journal article; Peer reviewed, 2021)A deeper understanding of the processes leading to problem framing and behind finding solutions to problems should help explain variability in the quality of the solutions to those problems. Using Sternberg’s WICS model ... -
Metaanalyse av effekten av fysisk aktivitet som behandling av angst på et klinisk utvalg
(Master thesis, 2010-11-21)Anxiety disorders are highly prevalent and are frequently under-treated. The majority of those suffering from anxiety disorders do not seek professional help, and the health care system is currently not able to meet the ... -
Metabolic alkalosis is the most common acid-base disorder in ICU patients
(Journal article, 2014-03-28) -
Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
(Journal article; Peer reviewed, 2020)Chronic cancer-related fatigue (CF) is a common and distressing condition in a subset of cancer survivors and common also after successful treatment of malignant lymphoma. The etiology and pathogenesis of CF is unknown, ... -
Metabolic and Epigenetic Regulation by Estrogen in Adipocytes
(Journal article; Peer reviewed, 2022-02-22)Sex hormones contribute to differences between males and females in body fat distribution and associated disease risk. Higher concentrations of estrogens are associated with a more gynoid body shape and with more fat storage ... -
Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study
(Peer reviewed; Journal article, 2019-12-04)Background: The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative ... -
Metabolic disorders: role of pregnane X receptor, fibroblast growth factor 19 and persistent organic pollutants
(Doctoral thesis, 2020-06-08)The incidence of obesity and correlated metabolic abnormalities has increased dramatically in the last decades and constitutes a huge burden on healthcare systems and economies. It is therefore important to increase our ... -
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
(Peer reviewed; Journal article, 2020)Background: We aimed at exploring potential pathophysiological processes across psychotic disorders, applying metabolomics in a large and well-characterized sample of patients and healthy controls. Methods: Patients with ... -
Metabolic effects of diet containing blue mussel (Mytilus edulis) and blue mussel-fed salmon in a mouse model of obesity
(Journal article; Peer reviewed, 2023)Alternative feed ingredients for farmed salmon are warranted due to increasing pressure on wild fish stocks. As locally farmed blue mussels may represent an environmentally sustainable substitute with a lower carbon ... -
Metabolic factors and the risk of small intestine cancers: Pooled study of 800 000 individuals in the metabolic syndrome and cancer project
(Journal article; Peer reviewed, 2021)To explore the largely unknown etiology of small intestine cancer, we examinedmetabolic factors and risk of small intestine cancer overall and by subtypes. Among404 220 women and 403 265 men in six European cohorts, we ... -
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines
(Journal article; Peer reviewed, 2022)Background Most in vitro cancer cell experiments have been performed using 2D models. However, 3D spheroid cultures are increasingly favored for being more representative of in vivo tumor conditions. To overcome the ... -
Metabolic pathways and physiological functions of organic and inorganic trace minerals in Atlantic Salmon
(Doctoral thesis, 2024-09-05)Mineralernæring spiller en nøkkelrolle for helse, velferd og prestasjonen til oppdrettet Atlantisk laks (Salmo salar), da den påvirker ulike fysiologiske prosesser, avgjørende for vekst, metabolisme og immunfunksjon. Blant ... -
Metabolic predictors of pain, fatigue, depression and quality of life in people with long-term type 1 diabetes—the Dialong study
(Journal article; Peer reviewed, 2022)Aim To examine associations of metabolic parameters (mean 30 years' time-weighted HbA1c and low-density lipoprotein-cholesterol [LDL-c], current methionine sulfoxide [MetSO], advanced glycation end products [AGEs], ... -
Metabolic profiles of placenta in preeclampsia using HR-MAS MRS metabolomics
(Peer reviewed; Journal article, 2015-12)Introduction Preeclampsia is a heterogeneous gestational disease characterized by maternal hypertension and proteinuria, affecting 2–7% of pregnancies. The disorder is initiated by insufficient placental development, but ...