• Physical activity in pregnancy: a Norwegian-Swedish mother-child birth cohort study 

      Carlsen, Oda Cecilie; Gudmundsdóttir, Hrefna Katrín; Bains, Karen Eline Stensby; Bertelsen, Randi Jacobsen; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Endre, Kim Magnus Advocaat; Granum, Berit; Haugen, Guttorm; Hedlin, Gunilla; Jonassen, Christine M; Kreyberg, Ina; Landrø, Linn Aina Ysland; Olsson, Caroline-Aleksi; Nordlund, Björn; Nordhagen, Live Solveig; Pehrson, Kristian; Saunders, Carina M.; Sjøborg, Katrine Dønvold; Skjerven, Håvard Ove; Staff, Anne Cathrine; Svanes, Cecilie; Söderhall, Cilla; Vettukattil, Riyas; Værnesbranden, Caren Magdalena Rydland; Wiik, Johanna; Rehbinder, Eva Maria (Journal article; Peer reviewed, 2021)
      BACKGROUND Physical activity during pregnancy is important for maternal and offspring health. Optimal conditions during pregnancy may help reduce the burden of noncommunicable diseases. National and international guidelines ...
    • Place of upbringing in early childhood as related to inflammatory bowel diseases in adulthood: A population-based cohort study in Northern Europe 

      Timm, Signe; Svanes, Cecilie; Janson, Christer; Sigsgaard, Torben; Johannessen, Ane; Gíslason, Thorarinn; Jõgi, Rain; Omenaas, Ernst; Forsberg, Bertil; Torén, Kjell; Holm, Mathias; Bråbäck, Lennart; Schlünssen, Vivi (Peer reviewed; Journal article, 2014-06)
      Background The two inflammatory bowel diseases (IBD), ulcerative colitis and Crohn's disease, has increased rapidly during the twentieth century, but the aetiology is still poorly understood. Impaired immunological competence ...
    • Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring’s body weight 

      Hammer, Barbara; Kadalayil, Latha; Boateng, Eistine; Buschmann, Dominik; Rezwan, Faisal I.; Wolff, Martin; Reuter, Sebastian; Bartel, Sabine; Knudsen, Gerd Toril Mørkve; Svanes, Cecilie; Holloway, John W.; Krauss-Etschmann, Susanne (Journal article; Peer reviewed, 2021)
      Background Active smoking has been reported among 7% of teenagers worldwide, with ages ranging from 13 to 15 years. An epidemiological study suggested that preconceptional paternal smoking is associated with adolescent ...
    • Predictors of microbial agents in dust and respiratory health in the Ecrhs 

      Tischer, Christina; Zock, Jan-Paul; Valkonen, Maria; Doekes, Gert; Guerra, Stefano; Heederick, Dick; Jarvis, Deborah; Norbäck, Dan; Olivieri, Mario; Sunyer, Jordi; Svanes, Cecilie; Täubel, Martin; Thiering, Elisabeth; Verlato, Guiseppe; Hyvärinen, Anne; Heinrich, Joachim (Peer reviewed; Journal article, 2015-05-02)
      Background Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to assess ...
    • Prenatal and prepubertal exposures to tobacco smoke in men may cause lower lung function in future offspring: a three-generation study using a causal modelling approach 

      Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndis; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali C.; Forsberg, Bertil; Real, Francisco Gomez; Holloway, John W.; Holm, Mathias; Janson, Christer; Jõgi, Nils O.; Jõgi, Rain; Malinovschi, Andrei; Marcon, Alessandro; Martínez-Moratalla Rovira, Jesús; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Torén, Kjell; Jarvis, Deborah; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Mechanistic research suggests that lifestyle and environmental factors impact respiratory health across generations by epigenetic changes transmitted through male germ cells. Evidence from studies on humans is very ...
    • Prevalence of allergic sensitization to storage mites in Northern Europe 

      Jögi, Nils Oskar; Kleppe Olsen, Robin; Svanes, Cecilie; Gislason, David; Gislason, Thorarinn; Schlünssen, Vivi; Sigsgaard, Torben; Sundbom, Fredrik; Storaas, Torgeir; Bertelsen, Randi Jacobsen (Peer reviewed; Journal article, 2020)
      Background: Allergic sensitization to storage mites has mostly been related to occupational exposures like farming, grain/cattle handling, whereas for non‐occupational settings, storage mite sensitization has been attributed ...
    • Prevalence of, and work-related risk factors for, hand eczema in a Norwegian general population (The HUNT Study) 

      Vindenes, Hilde Kristin; Svanes, Cecilie; Lygre, Stein Håkon Låstad; Hollund, Bjørg Eli; Langhammer, Arnulf; Bertelsen, Randi Jacobsen (Peer reviewed; Journal article, 2017-10)
      Background: Chemical exposures at work and at home may cause hand eczema. However, this has been scarcely described for Norway. Objectives: To investigate the prevalence of, and occupational risk factors for, hand eczema ...
    • Previous tuberculosis infection associated with increased frequency of asthma and respiratory symptoms in a Nordic–Baltic multicentre population study 

      Gyawali, Sanjay; Lopez Cervantes, Juan Pablo; Jögi, Nils Oskar; Mustafa, Tehmina; Johannessen, Ane; Janson, Christer; Holm, Mathias; Modig, Lars; Cramer, Christine; Gislason, Thorarinn; Svanes, Cecilie; Shigdel, Rajesh (Journal article; Peer reviewed, 2023)
      Background: Tuberculosis (TB) infection induces profound local and systemic, immunological and inflammatory changes that could influence the development of other respiratory diseases; however, the association between TB ...
    • A prospective study on the role of smoking, environmental tobacco smoke, indoor painting and living in old or new buildings on asthma, rhinitis and respiratory symptoms 

      Wang, Juan; Janson, Christer; Jõgi, Rain; Forsberg, Bertil; Gíslason, Þórarinn; Holm, Mathias; Torén, Kjell; Malinovschi, Andrei; Sigsgaard, Torben; Schlünssen, Vivi; Svanes, Cecilie; Johannessen, Ane; Bertelsen, Randi Jacobsen; Franklin, Karl A.; Norbäck, Dan (Journal article; Peer reviewed, 2021)
      We studied associations between tobacco smoke, home environment and respiratory health in a 10 year follow up of a cohort of 11,506 adults in Northern Europe. Multilevel logistic regression models were applied to estimate ...
    • Respiratory Health in Cleaners in Northern Europe: Is Susceptibility Established in Early Life? 

      Svanes, Øistein; Skorge, Trude Duelien; Johannessen, Ane; Bertelsen, Randi Jacobsen; Bråtveit, Magne; Forsberg, Bertil; Gislason, Thorarin; Holm, Mathias; Janson, Christer; Jögi, Rain; Macsali, Ferenc; Norbäck, Dan; Omenaas, Ernst; Gomez Real, Francisco; Schlünssen, Vivi; Sigsgaard, Torben; Wieslander, Gunilla; Zock, Jan-Paul; Aasen, Tor Olav Brøvig; Dratva, Julia; Svanes, Cecilie (Journal article; Peer reviewed, 2015)
      Rationale There is some evidence that maternal smoking increases susceptibility to personal smoking’s detrimental effects. One might question whether early life disadvantage might influence susceptibility to occupational ...
    • Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey 

      Voll-Aanerud, Marianne; Eagan, Tomas Mikal; Plana, Estel; Omenaas, Ernst; Bakke, Per; Svanes, Cecilie; Siroux, Valerie; Pin, Isabelle; Antó, Josep M.; Leynaert, Benedicte (Peer reviewed; Journal article, 2010-09-27)
      Background Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with HRQoL ...
    • Restrictive spirometry pattern is associated with low physical activity levels. A population based international study 

      Carsin, Anne-Elie; Fuertes, Elaine; Schaffner, Emmanuel; Jarvis, Debbie; Antó, Josep M.; Heinrich, Joachim; Bellisario, Valeria; Svanes, Cecilie; Keidel, Dirk; Imboden, Medea; Weyler, Joost; Nowak, Dennis; Martínez-Moratalla, Jesús; Gullón, José-Antonio; Sánchez Ramos, José Luis; Caviezel, Seraina; Beckmeyer-Borowko, Anna; Raherison, Chantal; Pin, Isabelle; Demoly, Pascal; Cerveri, Isa; Accordini, Simone; Gislason, Þórarinn; Torén, Kjell; Forsberg, Bertil; Janson, Christer; Jõgi, Rain; Emtner, Margareta; Gomez Real, Francisco; Raza, Wasif; Leynaert, Bénédicte; Pascual, Silvia; Guerra, Stefano; Dharmage, Shyamali C.; Probst-Hensch, Nicole; Garcia-Aymerich, Judith (Peer reviewed; Journal article, 2019)
      Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with ...
    • The risk of respiratory tract infections and antibiotic use in a general population and among people with asthma 

      Kisiel, Marta A.; Zhou, Xingwu; Björnsson, Eythor; Holm, Mathias; Dahlman-Höglund, Anna; Wang, Juan; Svanes, Cecilie; Norbäck, Dan; Franklin, Karl A.; Malinovschi, Andrei; Johannessen, Ane; Schlünssen, Vivi; Janson, Christer (Journal article; Peer reviewed, 2021)
      Aim The aim of this study was to investigate occupational, environmental, early life and other risk factors associated with respiratory infections and antibiotics use in a general population and among asthmatic ...
    • The role of epigenetics in multi-generational transmission of asthma: An NIAID workshop report-based narrative review 

      Wheatley, Lisa M.; Holloway, John W.; Svanes, Cecilie; Sears, Malcolm R.; Breton, Carrie; Fedulov, Alexey V.; Nilsson, Eric; Vercelli, Donata; Zhang, Hongmei; Togias, Alkis; Arshad, Syed Hasan (Journal article; Peer reviewed, 2022)
      There is mounting evidence that environmental exposures can result in effects on health that can be transmitted across generations, without the need for a direct exposure to the original factor, for example, the effect of ...
    • Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey 

      Flexeder, Claudia; Zock, Jan-Paul; Jarvis, Deborah; Verlato, Giuseppe; Olivieri, Mario; Benke, Geza; Abramson, Michael J.; Sigsgaard, Torben; Svanes, Cecilie; Torén, Kjell; Nowak, Dennis; Jõgi, Rain; Martínez-Moratalla, Jesús; Demoly, Pascal; Janson, Christer; Gíslason, Þórarinn; Bono, Roberto; Holm, Mathias; Franklin, Karl A.; Garcia-Aymerich, Judith; Siroux, Valérie; Leynaert, Bénédicte; Dorado Arenas, Sandra; Corsico, Angelo Guido; Pereira-Vega, Antonio; Probst-Hensch, Nicole; Urrutia Landa, Isabel; Schulz, Holger; Heinrich, Joachim (Peer reviewed; Journal article, 2019-02-14)
      Background: Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated ...
    • Transgenerational and intergenerational epigenetic inheritance in allergic diseases 

      Knudsen, Gerd Toril Mørkve; Rezwan, Faisal I.; Jiang, Yu; Karmaus, Wilfried; Svanes, Cecilie; Holloway, John W. (Peer reviewed; Journal article, 2018-09)
      It has become clear that early life (including in utero exposures) is a key window of vulnerability during which environmental exposures can alter developmental trajectories and initiate allergic disease development. ...
    • Trends in smoking initiation in Europe over 40 years: A retrospective cohort study 

      Marcon, Alessandro; Pesce, Giancarlo; Calciano, Lucia; Bellisario, Valeria; Dharmage, Shyamali C.; Garcia-Aymerich, Judith; Gislasson, Thorarinn; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Matheson, Melanie C.; Pirina, Pietro; Svanes, Cecilie; Villani, Simona; Zuberbier, Torsten; Minelli, Cosetta; Accordini, Simone (Journal article; Peer reviewed, 2018)
      Background Tobacco consumption is the largest avoidable health risk. Understanding changes of smoking over time and across populations is crucial to implementing health policies. We evaluated trends in smoking initiation ...
    • The urban-rural gradient in asthma: A population-based study in Northern Europe 

      Timm, Signe; Frydenberg, Morten; Janson, Christer; Campbell, Brittany; Forsberg, Bertil; Gíslason, Þórarinn; Holm, Mathias; Jõgi, Rain; Omenaas, Ernst; Sigsgaard, Torben; Svanes, Cecilie; Schlünssen, Vivi (Peer reviewed; Journal article, 2015-12-30)
      The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate ...
    • Zoonotic helminth exposure and risk of allergic diseases: A study of two generations in Norway 

      Jögi, Nils Oskar; Svanes, Cecilie; Siiak, Silver Peeter; Logan, Erin; Holloway, John W.; Igland, Jannicke; Johannessen, Ane; Levin, Michael E.; Gomez Real, Francisco; Schlünssen, Vivi; Horsnell, William G.C.; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2018)
      Background Animal and human studies indicate that definitive host helminth infections may confer protection from allergies. However, zoonotic helminths, such as Toxocara species (spp.), have been associated with increased ...