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N-Heterocyclic Carbene Complexes of Titanium vel Class of Catalysts for the Copolymerization of Cyclohexene Oxide with CO2
(Doctoral thesis, 2018-04-27)Regarding environmental, economic and political issues, the utilization of CO2 as C1 chemical feedstock has received a worldwide interest in the last decade. Indeed CO2 is considered as a greenhouse gas (submitted to strict ... -
N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus
(Journal article; Peer reviewed, 2020)N-alpha-acetyltransferase 80 (NAA80) was recently demonstrated to acetylate the N-terminus of actin, with NAA80 knockout cells showing actin cytoskeleton-related phenotypes, such as increased formation of membrane protrusions ... -
The N-terminal acetyltransferase Naa10 is essential for zebrafish development
(Peer reviewed; Journal article, 2015-08-06)N-terminal acetylation, catalysed by N-terminal acetyltransferases (NATs), is among the most common protein modifications in eukaryotes and involves the transfer of an acetyl group from acetyl-CoA to the α-amino group of ... -
N-terminal modifications of cellular proteins: the enzymes involved, their substrate specificities and biological effects
(Peer reviewed; Journal article, 2015-06-16)The vast majority of eukaryotic proteins are N-terminally modified by one or more processing enzymes. Enzymes acting on the very first amino acid of a polypeptide include different peptidases, transferases, and ligases. ... -
N-terminal pro-B-type natriuretic peptide as a prognostic indicator for 30-day mortality following out-of-hospital cardiac arrest: A prospective observational study
(Journal article; Peer reviewed, 2020-08-24)Background Early risk stratification applying cardiac biomarkers may prove useful in sudden cardiac arrest patients. We investigated the prognostic utility of early-on levels of high sensitivity cardiac troponin-T (hs-cTnT), ... -
N-terminal pro-B-type natriuretic peptide level at longterm follow-up after atrial fibrillation ablation: A marker of reverse atrial remodeling and successful ablation
(Peer reviewed; Journal article, 2011-10-13)Aims: We investigated the relationship between arrhythmia burden, left atrial volume (LAV) and N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) at baseline and after long-term follow-up of atrial fibrillation (AF) ... -
The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes
(Peer reviewed; Journal article, 2014-01-09)Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of catecholamine neurotransmitters, and a reduction in TH activity is associated with several neurological diseases. Human TH is regulated, among ... -
NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report
(Peer reviewed; Journal article, 2018)Background: The NAA10-NAA15 (NatA) protein complex is an N-terminal acetyltransferase responsible for acetylating ~ 40% of eukaryotic proteins. In recent years, NAA10 variants have been found in patients with an X-linked ... -
NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment
(Peer reviewed; Journal article, 2015-11-02)We report two brothers from a non-consanguineous Irish family presenting with a novel syndrome characterised by intellectual disability, facial dysmorphism, scoliosis and long QT. Their mother has a milder phenotype including ... -
NAA10 p.(D10G) and NAA10 p.(L11R) variants hamper formation of the NatA N-terminal acetyltransferase complex
(Journal article; Peer reviewed, 2020)The majority of the human proteome is subjected to N-terminal (Nt) acetylation catalysed by N-terminal acetyltransferases (NATs). The NatA complex is composed of two core subunits—the catalytic subunit NAA10 and the ribosomal ... -
NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy
(Journal article; Peer reviewed, 2020)Nearly half of all human proteins are acetylated at their N-termini by the NatA N-terminal acetyltransferase complex. NAA10 is evolutionarily conserved as the catalytic subunit of NatA in complex with NAA15, but may also ... -
Nabolagserfaringer etter flyktningkrisa
(Bergen Studies in Sociology;16/2022, Others, 2022) -
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease
(Journal article; Peer reviewed, 2022)We conducted a double-blinded phase I clinical trial to establish whether nicotinamide adenine dinucleotide (NAD) replenishment therapy, via oral intake of nicotinamide riboside (NR), is safe, augments cerebral NAD levels, ... -
Naive and adapted utilization of the GPU for general purpose computing
(Master thesis, 2017)In this thesis we will see that adaptive utilization of the graphical processing unit (GPU) has much better performance than naive utilization, but it takes longer time to implement and requires more knowledge about ... -
Nakkens betydning for postural kontroll
(Master thesis, 2012-11-01)Background: Neck disorders may affect as many as 70% of the general population at some point. Neck disorders are multidimensional, and are assumed to affect postural control. Manual therapists often see patients with neck ... -
Named Entity Extraction for Knowledge Graphs: A Literature Overview
(Journal article; Peer reviewed, 2020)An enormous amount of digital information is expressed as natural-language (NL) text that is not easily processable by computers. Knowledge Graphs (KG) offer a widely used format for representing information in ... -
Nancy Morejón desde las perspectivas del folklore, lo popular y la cultura clásica en Richard trajo su flauta y otros argumentos (1967).
(Master thesis, 2018-02-16)This thesis explores Nancy Morejón’s Richard trajo su flauta y otros argumentos, a collection of poetry published in 1967, only a few years after the triumph of the Cuban Revolution (1959). Drawing from textual references ... -
Nano to Micro Scale Modeling of Hydrate Phase Transition Kinetics
(Doctoral thesis, 2017-05-23) -
Nano-TiO2 penetration of oral mucosa: in vitro analysis using 3D organotypic human buccal mucosa models
(Peer reviewed; Journal article, 2016)BACKGROUND: Oral cavity is a doorway for a variety of products containing titanium dioxide (TiO2) nanoparticles (NPs) (nano-TiO2) such as food additives, oral healthcare products and dental materials. Their potential to ... -
Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes
(Peer reviewed; Journal article, 2016-07)This study aimed to evaluate the tumorigenic potential of functionalising poly(LLA-co-CL) scaffolds. The copolymer scaffolds were functionalised with nanodiamonds (nDP) or with nDP and physisorbed BMP-2 (nDP-PHY) to enhance ...