Browsing Bergen Open Research Archive by Title

Now showing items 36238-36257 of 36527

    • X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study 

      Hayden, Lystra P.; Hobbs, Brian D.; Busch, Robert; Cho, Michael H.; Liu, Ming; Lopes-Ramos, Camila M.; Lomas, David A.; Bakke, Per S.; Gulsvik, Amund; Silverman, Edwin K.; Crapo, James D.; Beaty, Terri H.; Laird, Nan M.; Lange, Christoph; DeMeo, Dawn L. (Journal article; Peer reviewed, 2023)
      Background The association between genetic variants on the X chromosome to risk of COPD has not been fully explored. We hypothesize that the X chromosome harbors variants important in determining risk of COPD related ...

    • X-chromosome variants are associated with aldosterone producing adenomas 

      Dutta, Ravi Kumar; Larsson, Malin; Arnesen, Thomas; Heie, Anette; Walz, Martin K.; Alesina, Piero; Gimm, Oliver; Söderkvist, Peter (Journal article; Peer reviewed, 2021)
      Aldosterone-producing adenomas (APAs) are a major cause of primary aldosteronism (PA) and are characterized by constitutively producing aldosterone, which leads to hypertension. Several mutations have been identified in ...

    • X-erne 

      Liland, Ørjan Kjellevold (Master thesis, 2020-06-24)

    • The X-factor in ART: does the use of assisted reproductive technologies influence DNA methylation on the X chromosome? 

      Romanowska, Julia; Nustad, Haakon Egdetveit; Page, Christian Magnus; Denault, William Robert Paul; Lee, Yunsung; Magnus, Maria Christine; Haftorn, Kristine Løkås; Gjerdevik, Miriam; Novakovic, Boris; Saffery, Richard; Gjessing, Håkon K.; lyle, robert; Magnus, Per Minor; Håberg, Siri Eldevik; Jugessur, Astanand (Journal article; Peer reviewed, 2023)
      Background Assisted reproductive technologies (ART) may perturb DNA methylation (DNAm) in early embryonic development. Although a handful of epigenome-wide association studies of ART have been published, none have investigated ...

    • X-Linked Genes and Risk of Orofacial Clefts: Evidence from Two Population-Based Studies in Scandinavia 

      Jugessur, Astanand; Skare, Øivind; Lie, Rolv Terje; Wilcox, Allen James; Christensen, Kaare; Christiansen, Lene; Nguyen, Truc Trung; Murray, Jeffrey Clark; Gjessing, Håkon K. (Peer reviewed; Journal article, 2012-06-19)
      Background: Orofacial clefts are common birth defects of complex etiology, with an excess of males among babies with cleft lip and palate, and an excess of females among those with cleft palate only. Although genes on the ...

    • X-ray microanalytical studies of initial mineralization in induced heterotopic bone formation in guinea pigs 

      Johannessen, Anne Christine; Nilsen, Rune; Bang, Gisle (Journal article, 1981)
      Allogenic demineralized dentin implanted in the abdominal wall of guinea pigs induced heterotopic osteoid and bone formation. Samples of this tissue were frozen at -140° C, freeze-dried at -80° C, infiltrated with Spurr® ...

    • XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase 

      Sharma, Abhishek; Erasimus, Hélène; Pinto, Lia; Caron, Marie-Christine; Gopaul, Diyavarshini; Peterlini, Thibault; Neumann, Katrin; Nazarov, Petr V.; Fritah, Sabrina; Klink, Barbara; Herold-Mende, Christel C.; Niclou, Simone Pierrette; Pasero, Philippe; Calsou, Patrick; Masson, Jean-Yves; Britton, Sébastien; Van Dyck, Eric (Journal article; Peer reviewed, 2021)
      Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected ...

    • XAI Text: A Domain-Specific Language for Developing an AI Pipeline 

      Brynjulfsen, Håvard (Master thesis, 2021-06-15)
      XAI Text: A Domain-Specific Language for Developing an AI Pipeline

    • Xanthoria calcicola (Teloschistaceae, Ascomycota) still present on bark in Sweden 

      Lindblom, Louise; Blom, Hans H. (Peer reviewed; Journal article, 2016)
      For almost twenty years Xanthoria calcicola was considered extinct on bark in Sweden. Here, we report X. calcicola growing on bark at 14 localities in Skåne, southernmost Sweden. In total, ca 300 thalli were observed on ...

    • Xenacoelomorpha's significance for understanding bilaterian evolution 

      Hejnol, Andreas; Pang, Kevin Scott (Journal article; Peer reviewed, 2016-08)
      The Xenacoelomorpha, with its phylogenetic position as sister group of the Nephrozoa (Protostomia + Deuterostomia), plays a key-role in understanding the evolution of bilaterian cell types and organ systems. Current studies ...

    • Xeno-free 3D Culture of Mesenchymal Stromal Cells For Bone Tissue Engineering 

      Shanbhag, Siddharth (Doctoral thesis, 2020)
      Clinical translation of innovative regenerative approaches using mesenchymal stromal cells (MSCs) is urgently needed for the treatment of challenging bone defects. The overall aim of this thesis, comprising of one systematic ...

    • Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues 

      Ali, Hassan Abdel-Raouf Abdel-Wahab; Suliman, Salwa; Osman, Tarig Al-Hadi; Carrasco Fernandez, Manuel; Bruland, Ove; Costea, Daniela Elena; Ræder, Helge; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2023)
      Background Induced pluripotent stem cells (iPS) can be generated from various somatic cells and can subsequently be differentiated to multiple cell types of the body. This makes them highly promising for cellular therapy ...

    • Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering 

      Shanbhag, Siddharth; Suliman, Salwa; Bolstad, Anne Isine; Stavropoulos, Andreas; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)
      Gingiva has been identified as a minimally invasive source of multipotent progenitor cells (GPCs) for use in bone tissue engineering (BTE). To facilitate clinical translation, it is important to characterize GPCs in xeno-free ...

    • Xenobiotic metabolism and its physiological consequences in high‑Antarctic Notothenioid fishes 

      Strobel, Anneli; Lille-Langøy, Roger; Segner, Helmut; Burkhardt-Holm, Patricia; Goksøyr, Anders; Karlsen, Odd André (Journal article; Peer reviewed, 2022)
      The Antarctic ecosystem is progressively exposed to anthropogenic contaminants, such as polycyclic aromatic hydrocarbons (PAHs). So far, it is largely unknown if PAHs leave a mark in the physiology of high-Antarctic fish. ...

    • Xenophobia, Political Society and the Mechanism of the Imitation of Affects 

      De Cuzzani, Paola Maria (Journal article; Peer reviewed, 2020)

    • Xerostomia in 75–85-year-olds: A longitudinal population study 

      Johansson, Ann-Katrin; Omar, Ridwaan; Mastrovito, Berit; Sannevik, Josefin; Carlsson, Gunnar E.; Johansson, Anders (Journal article; Peer reviewed, 2023)
      Background: Xerostomia can pose significant problems for many elderly people. Objectives: To investigate longitudinal changes in prevalence, persistence, progression, remission and incidence of xerostomia from age 75 ...

    • XHM: A system for detection of potential cross hybridizations in DNA microarrays 

      Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge (Peer reviewed; Journal article, 2004-08-27)
      Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be a source of error reducing the reliability ...

    • XNLP-Completeness for Parameterized Problems on Graphs with a Linear Structure 

      Bodlaender, Hans L.; Groenland, Carla; Jacob, Hugo; Jaffke, Lars; Lima, Paloma Thome de (Journal article; Peer reviewed, 2022)
      In this paper, we showcase the class XNLP as a natural place for many hard problems parameterized by linear width measures. This strengthens existing W[1]-hardness proofs for these problems, since XNLP-hardness implies ...

    • xOpat: eXplainable Open Pathology Analysis Tool 

      Horák, J.; Furmanová, K.; Kozlíková, B.; Brázdil, T.; Holub, P.; Kačenga, M.; Gallo, M.; Nenutil, R.; Byska, Jan; Rusňák, V. (Journal article; Peer reviewed, 2023)
      Histopathology research quickly evolves thanks to advances in whole slide imaging (WSI) and artificial intelligence (AI). However, existing WSI viewers are tailored either for clinical or research environments, but none ...

    • Xpert MTB/RIF assay can be used on archived gastric aspirate and induced sputum samples for sensitive diagnosis of paediatric tuberculosis 

      Singh, Sarman; Singh, Amit; Prajapati, Suneel; Kabra, Sushil K.; Lodha, Rakesh; Mukherjee, Aparna; Singh, Varinder; Hesseling, Anneke C.; Grewal, Harleen (Peer reviewed; Journal article, 2015-09-29)
      Background: Tuberculosis (TB) in children is neglected, mainly due to lack of sensitive diagnostic tools. Recently Xpert MTB/RIF assay has revolutionized the diagnostic field, but its usefulness in pediatric TB has not ...