Browsing Bergen Open Research Archive by Author "Pires-Afonso, Yolanda"
Now showing items 1-2 of 2
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Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency
Pires-Afonso, Yolanda; Muller, Arnaud; Grzyb, Kamil; Oudin, Anaïs; Yabo, Yahaya A.; Sousa, Carole; Scafidi, Andrea; Poli, Aurélie; Cosma, Antonio; Halder, Rashi; Coowar, Djalil; Golebiewska, Anna; Skupin, Alexander; Niclou, Simone Pierrette; Michelucci, Alessandro (Journal article; Peer reviewed, 2022)In glioblastoma (GBM), tumour-associated microglia/macrophages (TAMs) represent the major cell type of the stromal compartment and contribute to tumour immune escape mechanisms. Thus, targeting TAMs is emerging as a promising ... -
Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma
Pires-Afonso, Yolanda; Niclou, Simone Pierrette; Michelucci, Alessandro (Journal article; Peer reviewed, 2020)Cancer heterogeneity and progression are subject to complex interactions between neoplastic cells and their microenvironment, including the immune system. Although glioblastomas (GBMs) are classified as ‘cold tumours’ with ...