Blar i Bergen Open Research Archive på forfatter "Ruhwald, Morten"
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IP-10 dried blood spots assay monitoring treatment efficacy in extrapulmonary tuberculosis in a low-resource setting
Hoel, Ida Marie; Jørstad, Melissa Davidsen; Marijani, Msafiri; Ruhwald, Morten; Mustafa, Tehmina; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2019-03-07)Treatment efficacy is difficult to evaluate in extrapulmonary tuberculosis (EPTB) patients. Interferon-γ inducible protein (IP-)10 has been suggested as a biomarker for response to treatment. We have investigated if IP-10 ... -
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Jenum, Synne; Tonby, Kristian; Rueegg, Corina Silvia; Ruhwald, Morten; Kristiansen, Max Per; Bang, Peter; Olsen, Inge Christoffer; Sellæg, Kjersti; Røstad, Kjerstin; Mustafa, Tehmina; Tasken, Kjetil; Kvale, Dag; Mortensen, Rasmus; Riise, Anne Margarita Dyrhol (Journal article; Peer reviewed, 2021)Host-directed-therapy strategies are warranted to fight tuberculosis. Here we assess the safety and immunogenicity of adjunctive vaccination with the H56:IC31 candidate and cyclooxygenase-2-inhibitor treatment (etoricoxib) ... -
Prevalence of Mycobacterium tuberculosis infection as measured by the QuantiFERON-TB Gold assay and ESAT-6 free IGRA among adolescents in Mwanza, Tanzania
Jeremiah, Kidola; Lyimo, Eric; Ritz, Christian; PrayGod, George; Rutkowski, Kathryn Tucker; Korsholm, Karen Smith; Ruhwald, Morten; Tait, Dereck; Grewal, Harleen; Faurholt-Jepsen, Daniel (Journal article; Peer reviewed, 2021)Background The prevalence of latent tuberculosis infection (LTBI) is vastly higher than that of tuberculosis (TB) disease and this enormous reservoir of individuals with LTBI impacts the global TB control strategy. ...