Browsing Bergen Open Research Archive by Author "Arsin, Hasan"
Now showing items 1-3 of 3
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Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
Røyseth, Victoria; M. Hurysz, Brianna; Kaczorowska, Anna-Karina; Dorawa, Sebastian; Fedøy, Anita-Elin; Arsin, Hasan; Sá M. Serafim, Mateus; A. Myers, Samuel; Werbowy, Olesia; Kaczorowski, Tadeusz; Stokke, Runar; O'Donoghue, Anthony J.; Steen, Ida Helene (Journal article; Peer reviewed, 2023)Deep-sea hydrothermal vents offer unique habitats for heat tolerant enzymes with potential new enzymatic properties. Here, we present the novel C11 protease globupain, which was prospected from a metagenome-assembled genome ... -
Exploring codon adjustment strategies towards Escherichia coli-based production of viral proteins encoded by HTH1, a novel prophage of the marine bacterium Hypnocyclicus thermotrophus
Arsin, Hasan; Jasilionis, Andrius; Dahle, Håkon; Sandaa, Ruth-Anne; Stokke, Runar; Eva, Nordberg Karlsson; Steen, Ida Helene (Journal article; Peer reviewed, 2021)Marine viral sequence space is immense and presents a promising resource for the discovery of new enzymes interesting for research and biotechnology. However, bottlenecks in the functional annotation of viral genes and ... -
Mutational analysis of the pro-peptide of a marine intracellular subtilisin protease supports its role in inhibition
Bjerga, Gro Elin Kjæreng; Larsen, Øivind; Arsin, Hasan; Williamson, Adele Kim; Garcia-Moyano, Antonio; Leiros, Ingar; Puntervoll, Pål (Peer reviewed; Journal article, 2018-09)Intracellular subtilisin proteases (ISPs) have important roles in protein processing during the stationary phase in bacteria. Their unregulated protein degrading activity may have adverse effects inside a cell, but little ...