Browsing Bergen Open Research Archive by Author "Berezovsky, Igor"
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Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins
Goncearenco, Alexander; Ma, Binguang; Berezovsky, Igor (Peer reviewed; Journal article, 2014)DNA, RNA and proteins are major biological macromolecules that coevolve and adapt to environments as components of one highly interconnected system. We explore here sequence/structure determinants of mechanisms of adaptation ... -
SPACER: server for predicting allosteric communication and effects of regulation
Goncearenco, Alexander; Mitternacht, Simon; Yong, Taipang; Eisenhaber, Birgit; Eisenhaber, Frank; Berezovsky, Igor (Peer reviewed; Journal article, 2013-06-03)The SPACER server provides an interactive framework for exploring allosteric communication in proteins with different sizes, degrees of oligomerization and function. SPACER uses recently developed theoretical concepts based ...