• Associations of pregnancy-related factors and birth characteristics with risk of endometrial cancer: A Nordic population-based case-control study 

      Trabert, Britton; Troisi, Rebecca; Grotmol, Tom; Ekbom, Anders; Engeland, Anders; Gissler, Mika; Glimelius, Ingrid; Madanat-Harjuoja, Laura M.; Sørensen, Henrik Toft; Tretli, Steinar; Ording, Anne Gulbech; Bjørge, Tone (Peer reviewed; Journal article, 2019)
      Many pregnancy‐related factors are associated with reduced endometrial cancer risk. However, it remains unclear whether pregnancy‐related complications (e.g., hypertensive conditions) are associated with risk and whether ...
    • Atypical glandular lesions of the cervix and risk of cervical cancer 

      Graue, Renate; Lönnberg, Stefan; Skare, Gry Baadstrand; Sæther, Solbjørg Makalani Myrtveit; Bjørge, Tone (Journal article; Peer reviewed, 2020)
      Introduction Cytology screening has been effective in reducing risks for cervical squamous cell carcinoma but less so for adenocarcinoma. We explored the association of atypical glandular cells or absence of glandular ...
    • Blood glucose and risk of incident and fatal cancer in the metabolic syndrome and cancer project (me-can): analysis of six prospective cohorts 

      Stocks, Tanja; Rapp, Kilian; Bjørge, Tone; Manjer, Jonas; Ulmer, Hanno; Selmer, Randi Marie; Lukanova, Annekatrin; Johansen, Dorthe; Concin, Hans; Tretli, Steinar; Hallmans, Göran; Jonsson, Håkan; Stattin, Pär (Peer reviewed; Journal article, 2009-12-22)
      Background: Prospective studies have indicated that elevated blood glucose levels may be linked with increased cancer risk, but the strength of the association is unclear. We examined the association between blood glucose ...
    • Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults 

      Daltveit, Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders; Ekbom, Anders; Gissler, Mika; Glimelius, Ingrid; Grotmol, Tom; Madanat-Harjuoja, Laura M.; Ording, Anne Gulbech; Sæther, Solbjørg Makalani Myrtveit; Sørensen, Henrik Toft; Troisi, Rebecca; Bjørge, Tone (Journal article; Peer reviewed, 2020)
      Objective To examine associations between birth defects and cancer from birth into adulthood. Design Population based nested case-control study. Setting Nationwide health registries in Denmark, Finland, Norway, ...
    • Cervical cancer in women under 30 years of age in Norway: a population-based cohort study 

      Gravdal, Brit Helene; Lönnberg, Stefan; Skare, Gry Baadstrand; Sulo, Gerhard; Bjørge, Tone (Journal article; Peer reviewed, 2021)
      Background We compared women with incident cervical cancer under the age of 30 with older women with regard to stage, morphology, screening history and cervical cancer mortality in a population-based cohort study. Methods We ...
    • Economic independence in survivors of cancer diagnosed at a young age: A Norwegian national cohort study 

      Gunnes, Maria Winther; Lie, Rolv T.; Bjørge, Tone; Syse, Astri; Ruud, Ellen; Wesenberg, Finn; Moster, Dag (Peer reviewed; Journal article, 2016-12)
      BACKGROUND: The impact of cancer on socioeconomic outcomes is attracting attention as the number of survivors of cancer in young age continues to rise. This study examines economic independence in a national cohort of ...
    • The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 

      Kamangar, Farin; Nasrollahzadeh, Dariush; Safiri, Saeid; Sepanlou, Sadaf G; Fitzmaurice, Christina; Ikuta, Kevin S.; Bisignano, Catherine; Islami, Farhad; Roshandel, Gholamreza; Lim, Stephen S; Abolhassani, Hassan; Abu-Gharbieh, Eman; Adedoyin, Rufus Adesoji; Advani, Shailesh M.; Ahmed, Muktar Beshir; Aichour, Miloud Taki Eddine; Akinyemiju, Tomi; Akunna, Chisom Joyqueenet; Alahdab, Fares; Alipour, Vahid; Bjørge, Tone; Almasi-Hashiani, Amir (Journal article; Peer reviewed, 2020)
      Background Oesophageal cancer is a common and often fatal cancer that has two main histological subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma. Updated statistics on the incidence and mortality ...
    • Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. 

      Kyu, Hmwe Hmwe; Abate, Degu; Abate, Kalkidan Hassen; Abay, Solomon M.; Abbafati, Cristiana; Abbasi, Nooshin; Abbastabar, Hedayat; Abd-Allah, Foad; Abdela, Jemal; Abdelalim, Ahmed; Abdollahpour, Ibrahim; Abdulkader, Rizwan Suliankatchi; Stovner, Lars Jacob; Bjørge, Tone; Knudsen, Ann Kristin; Øverland, Simon Nygaard; Weiderpass, Elisabete; Eggen, Anne Elise; Htet, Aung Soe; Kisa, Adnan; Skirbekk, Vegard Fykse; Sulo, Gerhard; Steiner, Timothy J.; Murray, Christopher J L (Peer reviewed; Journal article, 2018-11-08)
      Background How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, ...
    • High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer 

      Mauland, Karen Klepsland; Trovik, Jone; Wik, Elisabeth; Ræder, Maria B.; Njølstad, Tormund Salvesen; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Bjørge, Tone; Akslen, Lars A.; Salvesen, Helga Birgitte (Peer reviewed; Journal article, 2011)
      Background: Endometrial cancer incidence is increasing in industrialised countries. High body mass index (BMI, kg m−2) is associated with higher risk for disease. We wanted to investigate if BMI is related to clinico-pathological ...
    • HPV DNA testing improves CIN2+ risk stratification and detection of CIN2+ in delayed triage of ASCUS and LSIL. A population-based follow-up study from Western Norway 

      Budal, Elisabeth Berge; Haugland, Hans Kristian; Skar, Robert; Mæhle, Bjørn Ove; Bjørge, Tone; Vintermyr, Olav Karsten (Peer reviewed; Journal article, 2014-02)
      In Norway, Pap smears with atypical squamous cells of uncertain significance (ASCUS) and low-grade squamous intraepithelial lesions (LSIL) are triaged after 6 months. The aim of the study was to evaluate effects of ...
    • Implementing medical abortion with mifepristone and misoprostol in Norway 1998-2013 

      Løkeland, Mette; Bjørge, Tone; Iversen, Ole-Erik; Akerkar, Rupali; Bjørge, Line (Peer reviewed; Journal article, 2017)
      Background: Medical abortion with mifepristone and misoprostol was introduced in Norway in 1998, and since then there has been an almost complete change from predominantly surgical to medical abortions. We aimed to describe ...
    • Life expectancy and disease burden in the Nordic countries: results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 

      Kisa, Adnan; Knudsen, Ann Kristin; Allebeck, Peter; Tollånes, Mette Christophersen; Skogen, Jens Christoffer; Iburg, Kim Moesgaard; McGrath, John J; Juel, Knud; Agardh, Emilie Elisabet; Arnlöv, Johan; Bjørge, Tone; Carrero, Juan J.; Cederroth, Christopher R; Eggen, Anne Elise; El-Khatib, Ziad; Lycke Ellingsen, Christian; Fereshtehnejad, Seyed-Mohammad; Gissler, Mika; Hadkhale, Kishor; Havmoeller, Rasmus; Johansson, Lars; Juliusson, Petur Benedikt; Kiadaliri, Aliasghar A.; Kisa, Sezer; Lallukka, Tea; Mekonnen, Teferi; Meretoja, Tuomo J.; Meretoja, Atte; Naghavi, Mohsen; Neupane, Subas; Nguyen, Truc Trung; Petzold, Max; Plana-Ripoll, Oleguer; Shiri, Rahman; Sigurvinsdottir, Rannveig; Skirbekk, Vegard; Skou, Søren T; Sigfusdottir, Inga Dora; Steiner, Timothy J.; Sulo, Gerhard; Truelsen, Thomas Clement; Vasankari, Tommi Juhani; Weiderpass, Elisabete; Vollset, Stein Emil; Vos, Theo; Øverland, Simon (Peer reviewed; Journal article, 2019-12-01)
      Background The Nordic countries have commonalities in gender equality, economy, welfare, and health care, but differ in culture and lifestyle, which might create country-wise health differences. This study compared life ...
    • Linear age-course effects on the associations between body mass index, triglycerides, and female breast and male liver cancer risk: An internal replication study of 800,000 individuals 

      Häggström, Christel; Jonsson, Håkan; Bjørge, Tone; Nagel, Gabriele; Manjer, Jonas; Ulmer, Hanno; Drake, Isabel; Ghaderi, Sara; Lang, Alois; Engeland, Anders; Stattin, Pär; Stocks, Tanja (Peer reviewed; Journal article, 2019)
      Apart from the consistently observed differential association between obesity and breast cancer risk by menopausal status, the associations between obesity and other metabolic imbalances with risks of cancers have not been ...
    • Long Term Association between Serum 25-Hydroxyvitamin D and Mortality in a Cohort of 4379 Men 

      Meyer, Haakon E; Støer, Nathalie; Samuelsen, Sven Ove; Blomhoff, Rune; Robsahm, Trude Eid; Brustad, Magritt; Giovannucci, Edward L; Bjørge, Tone (Peer reviewed; Journal article, 2016-03-17)
      Objective A number of observational studies have shown an inverse association between circulating 25-hydroxyvitamin D and total mortality, but a reverse J-shaped association has also been reported. In a large nested ...
    • Maternal use of folic acid and multivitamin supplements and infant risk of birth defects in Norway, 1999–2013 

      Gildestad, Trude; Bjørge, Tone; Haaland, Øystein Ariansen; Klungsøyr, Kari; Vollset, Stein Emil; Øyen, Nina (Journal article; Peer reviewed, 2020)
      The association between folic acid supplementation and birth defects other than neural tube defects (NTD) remains unclear. We used a log-binomial regression model to investigate if periconceptional folic acid and/or ...
    • Metabolic factors and the risk of small intestine cancers: Pooled study of 800 000 individuals in the metabolic syndrome and cancer project 

      Nagel, Gabriele; Bjørge, Tone; Jaensch, Andrea; Peter, Raphael Simon; Häggström, Christel; Lang, Alois; Engeland, Anders; Teleka, Stanley; Jirström, Karin; Lindquist, David; Stattin, Pär; Ulmer, Hanno; Concin, Hans; Stocks, Tanja (Journal article; Peer reviewed, 2021)
      To explore the largely unknown etiology of small intestine cancer, we examinedmetabolic factors and risk of small intestine cancer overall and by subtypes. Among404 220 women and 403 265 men in six European cohorts, we ...
    • Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective study of 580 000 subjects within the Me-Can project 

      Lindkvist, Björn; Johansen, Dorthe; Stocks, Tanja; Concin, Hans; Bjørge, Tone; Almquist, Martin; Häggström, Christel; Engeland, Anders; Hallmans, Göran; Nagel, Gabriele; Jonsson, Håkan; Selmer, Randi; Ulmer, Hanno; Tretli, Steinar; Stattin, Pär; Manjer, Jonas (Peer reviewed; Journal article, 2014-02-18)
      Background: Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC related ...
    • Metabolic risk score and cancer risk: pooled analysis of seven cohorts 

      Stocks, Tanja; Bjørge, Tone; Ulmer, Hanno; Manjer, Jonas; Häggström, Christel; Nagel, Gabriele; Engeland, Anders; Johansen, Dorthe; Hallmans, Göran; Selmer, Randi; Concin, Hans; Tretli, Steinar; Jonsson, Håkan; Stattin, Pär (Peer reviewed; Journal article, 2015)
      Background: There are few data on the joint influence of metabolic factors on risk of separate cancers. Methods: We analysed data on body mass index, blood pressure and plasma levels of glucose, total cholesterol and ...
    • Paternal characteristics associated with maternal periconceptional use of folic acid supplementation 

      Mortensen, Jan Helge Seglem; Øyen, Nina; Nilsen, Roy Miodini; Fomina, Tatiana; Tretli, Steinar; Bjørge, Tone (Peer reviewed; Journal article, 2018-05-30)
      Background: Maternal predictors of folic acid (FA) supplementation use to reduce offspring risk of neural tube defects are well known, while paternal determinants for maternal FA use are less known. Such knowledge is ...
    • Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Nitter, Mathilde Hjelle; Norgård, Benedicte Wentzel; De Vogel, Stefan; Eussen, Simone; Meyer, Klaus; Ulvik, Arve; Ueland, Per Magne; Nygård, Ottar; Vollset, Stein Emil; Bjørge, Tone; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Racine, Antoine; Cottet, Vanessa; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Grioni, Sara; Palli, Domenico; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Van Kranen, Henk J.; Peeters, Petra H. M.; Weiderpass, Elisabete; Dorronsoro, Miren; Jakszyn, Paula; Sánchez, María-José; Argüelles, Marcial Vicente; Huerta, José-Maria; Barricarte, Aurelio; Johansson, Matthias; Ljuslinder, Ingrid; Khaw, Kay Tee; Wareham, Nicholas J.; Freisling, Heinz; Duarte-Salles, Talita; Stepien, Magdalena; Gunter, Mark J.; Riboli, Élio B. (Peer reviewed; Journal article, 2014-08)
      Background Disturbances in one carbon metabolism may contribute to carcinogenesis by affecting methylation and synthesis of DNA. Choline and its oxidation product betaine are involved in this metabolism and can serve as ...