Browsing Bergen Open Research Archive by Author "Bjørndal, Bodil"
Now showing items 1-20 of 24
-
A chicken protein hydrolysate exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in Apoe−/− mice
Bjørndal, Bodil; Aloysius, Thomas Aquinas; Lund, Anders; Slizyte, Rasa; Bohov, Pavol; Carvajal, Ana Karina; Berge, Rolf Kristian (Peer reviewed; Journal article, 2019-01-13)Chicken protein hydrolysates (CPHs) generated from rest raw materials through enzymatic hydrolysis using Corolase PP or Alcalase were shown to reduce inflammation and stimulate hepatic mitochondrial fatty acid oxidation ... -
Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study
Strand, Elin; Pedersen, Eva Kristine Ringdal; Svingen, Gard Frodahl Tveitevåg; Schartum-Hansen, Hall; Rebnord, Eirik Wilberg; Bjørndal, Bodil; Seifert, Reinhard; Bohov, Pavol; Meyer, Klaus; Hiltunen, J. Kalervo; Nordrehaug, Jan Erik; Nilsen, Dennis W. T.; Berge, Rolf Kristian; Nygård, Ottar (Peer reviewed; Journal article, 2013-10-08)Background: A beneficial effect of a high n-3 long-chain polyunsaturated fatty acid (LCPUFA) intake has been observed in heart failure patients, who are frequently insulin resistant. We investigated the potential influence ... -
Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice
Skorve, Jon; Hilvo, Mika; Vihervaara, Terhi; Burri, Lena; Bohov, Pavol; Tillander, Veronika; Bjørndal, Bodil; Suoniemi, Matti; Laaksonen, Reijo; Ekroos, Kim; Berge, Rolf Kristian; Alexson, Stefan E.H. (Peer reviewed; Journal article, 2015-08-11)Background: Marine food is an important source of omega-3 fatty acids with beneficial health effects. Oils from marine organisms have different fatty acid composition and differ in their molecular composition. Fish oil ... -
Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice
Tillander, Veronika; Bjørndal, Bodil; Burri, Lena; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian; Alexson, Stefan E. H. (Peer reviewed; Journal article, 2014-04-27)Background: Marine derived oils are rich in long-chain polyunsaturated omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have long been associated with health promoting ... -
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation
Bjørndal, Bodil; Berge, Christ; Ramsvik, Marie Sannes; Svardal, Asbjørn; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian (Peer reviewed; Journal article, 2013-10-07)Background: There is growing evidence that fish protein hydrolysate (FPH) diets affect mitochondrial fatty acid metabolism in animals. The aim of the study was to determine if FPH could influence fatty acid metabolism and ... -
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study
Berge, Rolf Kristian; Ramsvik, Marie Sannes; Bohov, Pavol; Svardal, Asbjørn; Nordrehaug, Jan Erik; Rostrup, Espen; Bruheim, Inge; Bjørndal, Bodil (Peer reviewed; Journal article, 2015-12-15)Background: Lipid abnormalities, enhanced inflammation and oxidative stress seem to represent a vicious circle in atherogenesis, and therapeutic options directed against these processes seems like a reasonable approach in ... -
Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment
Skrede, Silje; Fernø, Johan; Bjørndal, Bodil; Brede, Wenche Rødseth; Bohov, Pavol; Berge, Rolf Kristian; Steen, Vidar Martin (Peer reviewed; Journal article, 2012-11-30)Background: Psychiatric patients often require chronic treatment with antipsychotic drugs, and while rats are frequently used to study antipsychotic-induced metabolic adverse effects, long-term exposure has only partially ... -
Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat
Strand, Elin; Bjørndal, Bodil; Nygård, Ottar; Burri, Lena; Berge, Christ; Bohov, Pavol; Christensen, Bjørn Jostein; Berge, Kjetil; Wergedahl, Hege; Viste, Asgaut; Berge, Rolf Kristian (Peer reviewed; Journal article, 2012-06-27)Background: Excess peroxisome proliferator-activated receptor (PPAR) stimulation has been associated with detrimental health effects including impaired myocardial function. Recently, supplementation with n-3 polyunsaturated ... -
A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats
Lindquist, Carine; Bjørndal, Bodil; Bakke, Hege Gilbø; Slettom, Grete; Karoliussen, Marie; Rustan, Arild; Thoresen, G. Hege; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2019-09-24)A fatty acid analogue, 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA), was previously shown to have hypolipidemic effects in rats by targeting mitochondrial activity predominantly in liver. This study aimed to determine ... -
Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats
Lysne, Vegard; Strand, Elin; Svingen, Gard Frodahl Tveitevåg; Bjørndal, Bodil; Pedersen, Eva Ringdal; Midttun, Øivind; Olsen, Thomas; Ueland, Per Magne; Berge, Rolf Kristian; Nygård, Ottar (Peer reviewed; Journal article, 2016-01-05)Plasma concentrations of metabolites along the choline oxidation pathway have been linked to increased risk of major lifestyle diseases, and peroxisome proliferator-activated receptors (PPARs) have been suggested to be ... -
A Phospholipid-Protein Complex from Antarctic Krill Reduced Plasma Homocysteine Levels and Increased Plasma Trimethylamine-N-Oxide (TMAO) and Carnitine Levels in Male Wistar Rats
Bjørndal, Bodil; Ramsvik, Marie Sannes; Lindquist, Carine; Nordrehaug, Jan Erik; Bruheim, Inge; Svardal, Asbjørn M.; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2015-09-08)Seafood is assumed to be beneficial for cardiovascular health, mainly based on plasma lipid lowering and anti-inflammatory effects of n-3 polyunsaturated fatty acids. However, other plasma risk factors linked to cardiovascular ... -
A phospholipid-protein complex from krill with antioxidative and immunomodulating properties reduced plasma triacylglycerol and hepatic lipogenesis in rats
Ramsvik, Marie Sannes; Bjørndal, Bodil; Bruheim, Inge; Bohov, Pavol; Berge, Rolf Kristian (Peer reviewed; Journal article, 2015-07-16)Dietary intake of marine omega-3 polyunsaturated fatty acids (n-3 PUFAs) can change the plasma profile from atherogenic to cardioprotective. In addition, there is growing evidence that proteins of marine origin may have ... -
Phospholipids from herring roe improve plasma lipids and glucose tolerance in healthy, young adults
Bjørndal, Bodil; Strand, Elin; Gjerde, Jennifer; Bohov, Pavol; Svardal, Asbjørn; Diehl, Bernd W. K.; Innis, Sheila M.; Berger, Alvin; Berge, Rolf Kristian (Peer reviewed; Journal article, 2014-05-17)Background: Herring roe is an underutilized source of n-3 polyunsaturated fatty acids (PUFAs) for human consumption with high phospholipid (PL) content. Studies have shown that PL may improve bioavailability of n-3 PUFAs. ... -
A protein extract from chicken reduces plasma homocysteine in rats
Lysne, Vegard; Bjørndal, Bodil; Vik, Rita; Nordrehaug, Jan Erik; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2015-06-04)The present study aimed to evaluate effects of a water-soluble protein fraction of chicken (CP), with a low methionine/glycine ratio, on plasma homocysteine and metabolites related to homocysteine metabolism. Male Wistar ... -
Receptor for activated C-kinase (RACK1) plays a central role in Ras-mediated signal transduction
Lillehaug, Johan; Myklebust, Line Merethe; Raae, Arnt Johan; Bjørndal, Bodil (Conference object; Peer reviewed, 2010-09-24) -
A salmon peptide diet alleviates experimental colitis as compared with fish oil
Grimstad, Tore; Bjørndal, Bodil; Cacabelos, Daniel; Aasprong, Ole Gunnar; Omdal, Roald; Svardal, Asbjørn M.; Bohov, Pavol; Pamplona, Reinald; Portero-Otin, Manuel; Berge, Rolf Kristian; Hausken, Trygve (Peer reviewed; Journal article, 2013-01-10)Fish oil (FO) has been shown to have anti-inflammatory properties in animal models of inflammatory bowel disease, but how fish peptides (FP) influence intestinal inflammation has been less studied. Male Wistar rats, divided ... -
A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice
Parolini, Cinzia; Vik, Rita; Busnelli, Marco; Bjørndal, Bodil; Holm, Sverre; Brattelid, Trond; Manzini, Stefano; Ganzetti, Giulia S.; Dellera, Federica; Halvorsen, Bente; Aukrust, Pål; Sirtori, Cesare R.; Nordrehaug, Jan Erik; Skorve, Jon; Berge, Rolf Kristian; Chiesa, Giulia (Peer reviewed; Journal article, 2014-05-19)Fish consumption is considered health beneficial as it decreases cardiovascular disease (CVD)-risk through effects on plasma lipids and inflammation. We investigated a salmon protein hydrolysate (SPH) that is hypothesized ... -
Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris
Strand, Elin; Pedersen, Eva Ringdal; Svingen, Gard Frodahl Tveitevåg; Olsen, Thomas; Bjørndal, Bodil; Karlsson, Therese; Dierkes, Jutta; Njølstad, Pål Rasmus; Mellgren, Gunnar; Tell, Grethe S.; Berge, Rolf Kristian; Svardal, Asbjørn M.; Nygård, Ottar (Peer reviewed; Journal article, 2017-02)Background: Excess levels of serum acylcarnitines, which are intermediate products in metabolism, have been observed in metabolic diseases such as type 2 diabetes mellitus. However, it is not known whether acylcarnitines ... -
Short-term activation of peroxisome proliferator-activated receptors α and γ induces tissue-specific effects on lipid metabolism and fatty acid composition in male Wistar rats
Strand, Elin; Lysne, Vegard; Grinna, Mari Lausund; Bohov, Pavol; Svardal, Asbjørn M.; Nygård, Ottar; Berge, Rolf Kristian; Bjørndal, Bodil (Peer reviewed; Journal article, 2019-06-12)Dietary fatty acids (FAs) affect certain metabolic routes, including pathways controlled by the peroxisome proliferator-activated receptors (PPARs), but tissue-specific effects are not well-defined. Thus, the aim was to ... -
Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats
Lysne, Vegard; Bjørndal, Bodil; Grinna, Mari Lausund; Midttun, Øivind; Ueland, Per Magne; Berge, Rolf Kristian; Dierkes, Jutta; Nygård, Ottar; Strand, Elin (Peer reviewed; Journal article, 2019-12-05)Introduction: Peroxisome proliferator-activated receptors (PPARs) have been suggested to be involved in the regulation of one-carbon metabolism. Previously we have reported effects on plasma concentrations of metabolites ...